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Obstetrics, Gynecology and Reproduction

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James Young Simpson and the transformation of attitudes to pain in obstetrics

https://doi.org/10.17749/2313-7347/ob.gyn.rep.2026.749

Abstract

Introducing obstetric anesthesia in the 19th century marked a pivotal stage in the development of medicine, fundamentally transforming the understanding that pain plays in childbirth. The work by James Young Simpson led to the widespread use of chloroform for labor analgesia and demonstrated an opportunity for safe and effective pain control. Simpson’s contributions were of the paramount importance for humanization of obstetric care and emergence of anesthesiology as an independent medical discipline, thereby highlighting a transition from the acceptance of pain to its targeted management.

About the Authors

V. Yu. Sashnina
Sechenov University
Russian Federation

Viktoria Yu. Sashnina

8 bldg. 2, Trubetskaya Str., Moscow 119048 



A. S. Russo
Sechenov University
Russian Federation

Arkady S. Russo 

8 bldg. 2, Trubetskaya Str., Moscow 119048 



N. A. Serdyukova
Sechenov University
Russian Federation

Natalia A. Serdyukova 

8 bldg. 2, Trubetskaya Str., Moscow 119048 



A. V. Vorobev
Sechenov University
Russian Federation

Alexander V. Vorobev, MD, Dr Sci Med. 

Scopus Author ID: 57191966265. WoS ResearcherID: F-8804-2017 

8 bldg. 2, Trubetskaya Str., Moscow 119048 



N. A. Makatsariya
Sechenov University
Russian Federation

Nataliya A. Makatsariya, MD, PhD.  

WoS ResearcherID: F-8406-2017 

8 bldg. 2, Trubetskaya Str., Moscow 119048 



References

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2. Lawrence C. Morton William Thomas Green (09 August 1819–15 July 1868), dentist and introducer of ether anesthesia. New York City: Oxford University Press, 2018. https://doi.org/10.1093/ANB/9780198606697.ARTICLE.1200646.

3. Cooper M.G., Haridas R.P. Sir James Young Simpson, Baronet (1811–1870). Anaesthesia and Intensive Care. 2019;47(3_suppl):4–5. https://doi.org/10.1177/0310057X19867097.

4. Tsvelyov Yu.V., Popov A.S. Sir James Young Simpson (1811–1870). [Ser Dzhejms Yang Simpson (Simpson, 1811–1870)]. Zhurnal akusherstva i zhenskih boleznej. 2009;58(4):93–9. (In Russ.).

5. Simpson J.Y. On a new anaesthetic agent, more efficient than sulphuric ether. Lancet. 1847;50(1264):549–50.

6. Caton D. John Snow's practice of obstetric anesthesia. Anesthesiology. 2000;92(1):247–52. https://doi.org/10.1097/00000542-200001000-00037.


Review

For citations:


Sashnina V.Yu., Russo A.S., Serdyukova N.A., Vorobev A.V., Makatsariya N.A. James Young Simpson and the transformation of attitudes to pain in obstetrics. Obstetrics, Gynecology and Reproduction. 2026;20(2):387-391. (In Russ.) https://doi.org/10.17749/2313-7347/ob.gyn.rep.2026.749

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)