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Placental site trophoblastic tumor during pregnancy complicated by uterine rupture

https://doi.org/10.17749/2313-7347/ob.gyn.rep.2020.122

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Abstract

The placental site trophoblastic tumor is a rare highly malignant form of trophoblastic disease, which occurs in as few as 0.4-2.0 % of all trophoblastic tumors. Available publications describes not more than 200 clinical cases of this pathology often affecting patients of reproductive age, thereby underscoring special importance of its diagnostics and treatment. Here we describe the rare clinical case of spontaneous uterine rupture in pregnant woman at 26 weeks of gestation carrying placental site trophoblastic tumor, previously undescribed in research literature. The complexity of diagnosing such pathology that resulted in antenatal fetal death and hysterectomy is demonstrated.

About the Authors

A. N. Sulima
S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University; Simferopol Clinical Maternity Hospital № 1
Russian Federation
Anna N. Sulima - MD, Dr Sci Med, Professor, Department of Obstetrics, Gynecology and Perinatology № 1, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russia; Obstetrician-Gynecologist, Simferopol State Clinical Maternity Hospital № 1, Simferopol.
5/7 Lenin Boulevard, Simferopol, Republic of Crimea 295006; 8 Vorovskogo Str., Simferopol, Republic of Crimea 295017.


D. A. Beglitse
S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University; Simferopol Clinical Maternity Hospital № 1
Russian Federation
Dmitriy A. Beglitse - MD, PhD, Associate Professor, Department of Obstetrics, Gynecology and Perinatology № 1, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University, Simferopol, Republic of Crimea, Russia; Chief physician, Simferopol Clinical Maternity Hospital № 1.
5/7 Lenin Boulevard, Simferopol, Republic of Crimea 295006; 8 Vorovskogo Str., Simferopol, Republic of Crimea 295017.


A. A. Davydova
S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University
Russian Federation
Aleksandra A. Davydova - MD, PhD, Associate Professor, Department of Pathological Anatomy with Sectional Course, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University.
5/7 Lenin Boulevard, Simferopol, Republic of Crimea 295006.


V. V. Voronaya
S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University
Russian Federation
Viktoriya V. Voronaya - MD, PhD, Assistant, Department of Obstetrics, Gynecology and Perinatology № 1, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University.
5/7 Lenin Boulevard, Simferopol, Republic of Crimea 295006.


A. N. Rybalka
S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University
Russian Federation
Anatoliy N. Rybalka - MD, Dr Sci Med, Professor, Academician of the Crimean Academy of Sciences, Department of Obstetrics, Gynecology and Perinatology № 1, S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University.
5/7 Lenin Boulevard, Simferopol, Republic of Crimea 295006.


P. N. Baskakov
S.I. Georgievsky Medical Academy, V.I. Vernadsky Crimean Federal University
Russian Federation

Petr N. Baskakov - MD, Dr Sci Med, Professor, Department of Obstetrics, Gynecology and Perinatology № 1, S.I. Georgievsky Medical Academy, V. I. Vernadsky Crimean Federal University.
5/7 Lenin Boulevard, Simferopol, Republic of Crimea 295006.



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For citation:


Sulima A.N., Beglitse D.A., Davydova A.A., Voronaya V.V., Rybalka A.N., Baskakov P.N. Placental site trophoblastic tumor during pregnancy complicated by uterine rupture. Obstetrics, Gynecology and Reproduction. 2020;14(5):667-673. (In Russ.) https://doi.org/10.17749/2313-7347/ob.gyn.rep.2020.122

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)