Obstetrics, Gynecology and Reproduction

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Vol 7, No 1 (2013)


6-7 507
Infections associated with pregnancy, labor and postpartum period pose a threat to the pregnant woman, fetus and newborn baby and remain a serious issue for physicians over several centuries. The preterm labor which often may not have a clear etiology is the major cause of neonatal deaths worldwide. The relationship between changes in vaginal microbiocenosis and preterm labor is not sufficiently well studied so far.
8-10 377
Healthy family is an objective criterion of population health and an assessment indicator of social and economic problems. The fraction of infertile couples in Russian Federation varies between 8% and 17% and currently demonstrates no clear trend towards declining. From a social welfare perspective it has not only physical,  familial or psychological repercussions but also social and demographic consequences.
11-16 267
The objective of this study was to optimize the preoperative assessment in transvaginal pelvic reconstructive plastic surgery for the treatment of pelvic organs prolapse. Materials and methods: We conducted the quantitative and qualitative analysis of vaginal biocenosis in 68 female patients before and after administration of Polygynax. It was shown that Polygynax improves vaginal biocenosis owing to the reduction of microbial content. Therefore, the use of Polygynax for the preoperative assessment can be an effective method of prophylaxis of infectious and inflammatory complications and promote tissue regeneration after transvaginal pelvic reconstructive plastic surgery for the treatment
of pelvic organs prolapse.
17-21 360
The review of the russian and foreign literature on pelvic organ prolapse in women and its genetic aspects. According to the literature, an association of pelvic organ prolapse (POP) with a number of single nucleotide polymorphisms (SNPs) on chromosome 9q21, which are involved in the formation of elastic fibers of the connective tissue (CT). The association also polymorphism fibullin – 5 (FBLN5) and lysyl oxidase – like 1 (LOXL1) and their
relationship to POP. Based on the literature, studies aimed at identifying the genetic nature of the POP, are incomplete and are important for the identification of risk groups who have a predisposition to POP, selecting the optimal policy for patients at risk and the initial stages of POP.
22-25 303
The pregnancy outcome depends on a stage of a current of disease by a virus hepatitis. The factors defining the forecast of disease at chronic virus hepatitises, activity of inflammatory process and intensity of formation fibrosis in a liver which can be estimated a noninvasive method is.
26-30 262
Surgical treatment of patients with stress urine incontinence is being carried out for over 130 year. Of particular interest is the implantation of tension-free sub-urethral synthetic sling (tension-free vaginal tape procedure – TVT) which is notable for its low rate of lower urinary tract injuries and high clinical effectiveness. The preoperative assessment
and postoperative care play an important role in tissue healing and patients’ fast recovery after surgery. This study aims at evaluation of the effectiveness of preoperative assessment and postoperative care in women with stress urine incontinence. Forty female patients suffering from stress urine incontinence and history of recurrent vulvovaginal candidiadis were examined and subjected to the TVT procedure. The postoperative follow-up period was between 1 and 3 months. Based on the results of patient questioning, good result was obtained in 40 (100%) patients at 3 months
post-operation. Bacterioscopy of vaginal smears from patients treated with Livarol in the postoperative period did not reveal the presence of Candida fungi at 1 or 3 months post-operation. Therefore, the successful surgical intervention mainly depends of careful selection of patients and the performance of a technically perfect surgical operation. Proper vaginal sanitation measures and postoperative wound management will secure fast patients’ recovery and reduction of their inpatient stay.
31-35 377
This article presents a literature survey on the pathogenesis of gestational diabetes mellitus and abnormal carbohydrate metabolism during pregnancy. Also, the effects of some medicinal drugs which may provoke hyperglycemia during pregnancy leading in turn to different perinatal and maternal complications are discussed.
36-40 296
The article presents modern possibilities of the use of hormonal contraceptives in the form of combined estrogen-gestagenic agents, of gestagenic contraceptives, intrauterine equipment, implants and adhesive bandages. Discussedmainissuesof efficiency, safety and acceptability of the use of these funds in the high-risk group for the development of complications.
41-44 306
The paper presents the data of meta-analyses and individual randomized studies on the effectiveness of magnesium sulfate as a drug to reduce the risk of cerebral palsy in the development of premature birth.
45-53 345
This article describes the features of the hemostatic system and endothelial function in pregnant patients who are at risk for obstetric complications: chronic hypertension, type 1 diabetes, gestational diabetes mellitus, epilepsy, a pathology of leg veins, miscarriage. Based on this study developed an algorithm for diagnosis of endothelial dysfunction
and pathology of the hemostatic system in these patients. Given the major pathogenetic aspects, provides detailed pharmacotherapy revealed pathology. Developed a scale of «the assessment of the thrombophilia and methods of its correction during pregnancy and on the background of extragenital pathology®», which allows you to identify and find a
differentiated pharmacotherapy with certain dosage, duration of the course in the dynamics and control, regardless of the methods and standards of determining the parameters of hemostasis.
54-56 488
In the paper, we present a clinical case developed medicinal hepatitis described the tactics of management of the patient with the use of hepatic protectors.

ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)