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THE BASIC POINTS OF SAFE MANAGEMENT OF PREGNANCY AND DELIVERY IN PATIENTS WITH MARFAN SYNDROME

https://doi.org/10.17749/2313-7347.2017.11.3.082-087

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Abstract

Marfan syndrome is dominantly inherited connective tissue diseases, associated with microfibrillar fiber connective tissue deficiency in vascular walls, heart valves, joints, dural membrane,  bones, and other organs. Diagnosis may be confirmed by clinical  criteria and molecular tests. Pregnancy bears a risk of fatal complications,  including aortic dissection, aortic root dilation, mitral valve insufficiency.  Women must be followed and managed in a high risk pregnancy unit by a team from obstetricians, cardiologists, anesthetists, pediatricians, neonatologists  and cardiac surgeons who are skilled in high risk pregnancies. This approach allows to avoid the serious maternal and fetal complications. Caesarean section should be offered for such patients, because it minimizes the hemodynamic changes, associated with vaginal delivery. Some authors recommend to perform post-cesarean hysterectomy, because of the high incidence of massive hemorrhage in postpartum.

About the Authors

L. S. Radetskaya
I.M. Sechenov First Moscow State Medical University, Health Ministry of Russian Federation
Russian Federation

Radetskaya Lyudmila Sergeevna – PhD, Associate Professor,  Department of Obstetrics and Gynecology, Faculty of Preventive Medicine.

Ul. Trubetskaya, 8, str. 2, Moscow, 119991



A. D. Makatsariya
I.M. Sechenov First Moscow State Medical University, Health Ministry of Russian Federation
Russian Federation

Makatsariya  Aleksander  Davidovich – MD, Corresponding Member of RAS,  Professor, Head of Department of Obstetrics and Gynecology, Faculty of Preventive  Medicine.

Ul. Trubetskaya, 8, str. 2, Moscow, 119991



V. O. Bitsadze
I.M. Sechenov First Moscow State Medical University, Health Ministry of Russian Federation
Russian Federation

Bitsadze Viсtoria Omarovna – MD, Professor,  Department of Obstetrics and Gynecology, Faculty of Preventive Medicine.

Ul. Trubetskaya, 8, str. 2, Moscow, 119991



N. M. Khamani
I.M. Sechenov First Moscow State Medical University, Health Ministry of Russian Federation
Russian Federation

Khamani Nadine Moktarovna – post-graduate student, Department of Obstetrics and Gynecology, Faculty of Preventive Medicine.

Ul. Trubetskaya, 8, str. 2, Moscow, 119991



D. V. Mitryuk
State Medical and Pharmaceutical University «Nicolae Testemitanu»
Moldova, Republic of

Mitryuk Diana Viktorovna – assistant, Department of Obstetrics and Gynecology.

Bul. Shtefan chel Mare, 165, Kishinev



N. A. Makatsariya
I.M. Sechenov First Moscow State Medical University, Health Ministry of Russian Federation
Russian Federation

Makatsariya  Nataliya Aleksandrovna  –  Assistant, Department of Obstetrics and Gynecology,  Faculty of Preventive Medicine.

Ul. Trubetskaya, 8, str. 2, Moscow, 119991



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For citation:


Radetskaya L.S., Makatsariya A.D., Bitsadze V.O., Khamani N.M., Mitryuk D.V., Makatsariya N.A. THE BASIC POINTS OF SAFE MANAGEMENT OF PREGNANCY AND DELIVERY IN PATIENTS WITH MARFAN SYNDROME. Obstetrics, Gynecology and Reproduction. 2017;11(3):82-87. https://doi.org/10.17749/2313-7347.2017.11.3.082-087

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)