HYPERPLASIC PROCESS OF ENDOMETRIUM: FEATURES OF PROLIFERATIVE ACTIVITY WHEN COMBINED WITH CHRONIC ENDOMETRITIS
Abstract
A comprehensive pathomorphological and immunohistochemical study of the scales of endometrium is carried out. With hyperplastic the process of endometrium and chronic endometritis are noted the high proliferating activity of the stroma of glands (Ki-67), the high expression of TFR- and SEFR, which indicates the actively going processes of neoangiogenezes and disturbance in the extracellular matrix. Inflammation raises to a higher power the proliferating activity of epithelium and stroma of the hyperplasiized endometrium, and it means, creates favorable conditions for the atypical transformation of cells.
About the Authors
N. A. Sheshukova
ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития России,
Городская клиническая больница № 14 им. В.Г. Короленко департамента здравоохранения г. Москвы
Russian Federation
Russian Federation
I. O. Makarov
ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития России,
Городская клиническая больница № 14 им. В.Г. Короленко департамента здравоохранения г. Москвы
Russian Federation
Russian Federation
T. V. Ovsyannikova
ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития России,
Городская клиническая больница № 14 им. В.Г. Короленко департамента здравоохранения г. Москвы
Russian Federation
Russian Federation
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Review
For citations:
Sheshukova N.A., Makarov I.O., Ovsyannikova T.V. HYPERPLASIC PROCESS OF ENDOMETRIUM: FEATURES OF PROLIFERATIVE ACTIVITY WHEN COMBINED WITH CHRONIC ENDOMETRITIS. Obstetrics, Gynecology and Reproduction. 2011;5(3):10-15. (In Russ.)
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