USE OF GONADOTROPIN-RELEASING HORMONE AGONISTS IN TREATMENT OF RECURRENT PRE-MENSTRUAL ENDOMETRIAL HYPERPLASIA
Abstract
This article presents modern insights into the pathogenesis of endometrium hyperplastic processes, matrix metalloproteinases and their tissue inhibitors, and their role in development of endometrium hyperplasia. A pathogenetic substantiation is given for use of Lucrin Depot, which affects the key molecular mechanisms of development of hyperplastic processes, with the objective of pharmacological correction of this pathology
About the Authors
Yu. E. Dobrokhotova
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation
Russian Federation
L. V. Saprykina
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation
Russian Federation
N. A. Litvinova
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation
Russian Federation
Yu. N. Zadonskay
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation
Russian Federation
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Review
For citations:
Dobrokhotova Yu.E., Saprykina L.V., Litvinova N.A., Zadonskay Yu.N. USE OF GONADOTROPIN-RELEASING HORMONE AGONISTS IN TREATMENT OF RECURRENT PRE-MENSTRUAL ENDOMETRIAL HYPERPLASIA. Obstetrics, Gynecology and Reproduction. 2011;5(1):15-17. (In Russ.)
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