Preview

Obstetrics, Gynecology and Reproduction

Advanced search

USE OF GONADOTROPIN-RELEASING HORMONE AGONISTS IN TREATMENT OF RECURRENT PRE-MENSTRUAL ENDOMETRIAL HYPERPLASIA

Full Text:

Abstract

This article presents modern insights into the pathogenesis of endometrium hyperplastic processes, matrix metalloproteinases and their tissue inhibitors, and their role in development of endometrium hyperplasia. A pathogenetic substantiation is given for use of Lucrin Depot, which affects the key molecular mechanisms of development of hyperplastic processes, with the objective of pharmacological correction of this pathology

About the Authors

Yu. E. Dobrokhotova
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation


L. V. Saprykina
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation


N. A. Litvinova
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation


Yu. N. Zadonskay
Department of obstetrics and gynecology of Moscow Faculty of GOU VPO Russian State Medical University of Roszdrav
Russian Federation


References

1. Болиева Г.У. Доброкачественные заболевания молочных желез при гиперпластических процессах эндо-и миометрия. Автореф. дис. …к.м.н. -Душанбе, 2006. -16 с.

2. Бохман Я.В. Руководство по онкогинекологии. Ст-Петербург, Фолиант, 2002, 542 с.

3. Задонская Ю.Н., Гиперпластические процессы эндометрия в пременопаузе: современные аспекты патогенеза и лечения.//Автореф. дисс. к. м. н. -М., 2008. -25 с

4. Литвинова Н.А. Состояние эндометрия у больных с сочетанной патологией эндо-и миометрия, перенесших эмболизацию маточных артерий в пременопаузальном периоде//Автореф. дисс. канд. мед. наук. М., 2009. -28 с.

5. Серов В.Н., Прилепская В.Н., Пшеничникова Т.Я. Гинекологическая эндокринология. Москва, Медицина, 1993, 499 с.

6. Curry T.E., Osteen K.G. The matrix metalloproteinase system: changes, regulation, and impact throughout the ovarian and uterine reproductive cycle. Endocr. Rev., 2003, Vol. 24, N 4, P. 428-465.

7. Malemud C.J. Matrix metalloproteinases (MMPs) in health and disease: an overview. Front. Biosci., 2006, N 11, P. 1696-1701.


For citation:


Dobrokhotova Yu.E., Saprykina L.V., Litvinova N.A., Zadonskay Yu.N. USE OF GONADOTROPIN-RELEASING HORMONE AGONISTS IN TREATMENT OF RECURRENT PRE-MENSTRUAL ENDOMETRIAL HYPERPLASIA. Obstetrics, Gynecology and Reproduction. 2011;5(1):15-17. (In Russ.)

Views: 157


ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)