Management of coagulopathy related to major obstetric bleeding: narrative review
https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.482
Abstract
Obstetric bleeding represents one of the main causes of maternal mortality worldwide. Along with hypertensive disorders it accounts for over half of maternal mortality cases. The implementation of strategies such as the "code red", increased institutionalized deliveries, early transfusions, and early obstetric alert system has reduced mortality. Cases of massive bleeding require admission to the Intensive Care Unit as they can progress to coagulopathy. This narrative review focuses on medications intended for the advanced management of coagulopathy in this population.
About the Authors
L. Correa-Pérez
Universidad del Rosario; Clínica Pediátrica Colsanitas y Mujer
Colombia
Colombia
Liliana Correa-Pérez, MD, PhD in Bioethics, Master's degree in Public Health
6-25 Str. 12C, Bogotá D.C. 111071
20-56 Str. 127, Bogotá 110911
S. Olaya-Garay
Universidad de Manizales
Colombia
Colombia
Sandra Olaya-Garay, MD
9a Str. No. 19-03, Manizales 170001
S. Mora-Martínez
Universidad de Manizales; Corporación Universitaria Empresarial Alexander von Humboldt
Russian Federation
Russian Federation
Santiago Mora-Martínez, MD
9a Str. No. 19-03, Manizales 170001
15 North – 46 Str. 13, Armenia 630008
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For citations:
Correa-Pérez L., Olaya-Garay S., Mora-Martínez S. Management of coagulopathy related to major obstetric bleeding: narrative review. Obstetrics, Gynecology and Reproduction. 2025;19(6):914–922. https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.482
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