The importance of iron deficiency and folic acid deficiency prevention upon pregnancy planning
V. S. Kuvaev,
V. V. Kazenashev,
O. S. Derevyanko,
A. L. Tikhomirov,
L. R. Garaeva,
N. L. Davydenko,
M. V. Maminova,
K. V. Lyapina,
N. V. Rurua https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.672
Abstract
Information published over the last decade on using iron supplements has been collected and systematized. The need for long-term iron supplementation and patient compliance has been updated and emphasized. The main requirements for current iron supplements today have been formulated, and the advantages of combining organic iron salts with folic acid as the most optimal and contemporary approach to the prevention and treatment of iron deficiency during pregnancy have been emphasized.
Keywords
iron deficiency anemia,
folic acid,
iron fumarate,
ferroptosis,
oxidative stress,
pregnancy,
folates,
iron
About the Authors
V. S. Kuvaev
Fomin Clinic
Russian Federation
Russian Federation
Vadim S. Kuvaev - MD, PhD.
17 bldg. 1, Dolgorukovskaya Str., Moscow 127006
V. V. Kazenashev
Russian University of Medicine, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Victor V. Kazenashev - MD, PhD.
4 Dolgorukovskaya Str., Moscow 127006
O. S. Derevyanko
Fomin Clinic
Russian Federation
Russian Federation
Olga S. Derevyanko - MD, PhD.
15A Michurinsky Prospekt, 119192 Moscow
A. L. Tikhomirov
Russian University of Medicine, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Alexander L. Tikhomirov - MD, Dr Sci Med, Prof.
4 Dolgorukovskaya Str., Moscow 127006
L. R. Garaeva
Zhukovsky Regional Clinical Hospital
Russian Federation
Russian Federation
Lilia R. Garaeva - MD, PhD.
1 Frunze Str., Zhukovsky, Moscow Region 140180
N. L. Davydenko
Central Clinical Hospital "Russian Railways-Medicine"
Russian Federation
Russian Federation
Natalya L. Davydenko - MD.
84 Volokolamskoe Shosse, Moscow 125367
M. V. Maminova
Russian University of Medicine, Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Maria V. Maminova.
4 Dolgorukovskaya Str., Moscow 127006
K. V. Lyapina
Zhukovsky Regional Clinical Hospital
Russian Federation
Russian Federation
Kristina V. Lyapina - MD.
1 Frunze Str., Zhukovsky, Moscow Region 140180
N. V. Rurua
Central Clinical Hospital "Russian Railways-Medicine"
Russian Federation
Russian Federation
Nana V. Rurua - MD.
84 Volokolamskoe Shosse, Moscow 125367
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Kuvaev V.S., Kazenashev V.V., Derevyanko O.S., Tikhomirov A.L., Garaeva L.R., Davydenko N.L., Maminova M.V., Lyapina K.V., Rurua N.V. The importance of iron deficiency and folic acid deficiency prevention upon pregnancy planning. Obstetrics, Gynecology and Reproduction. 2025;19(4):561-573. (In Russ.) https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.672
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