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Patrick Christopher Steptoe: the surgeon without which there would be no IVF

https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.636

Abstract

This article highlights key stages in the life and career of the British surgeon Patrick Christopher Steptoe, who played a key role in the development of assisted reproductive technologies. Having started his career as a laparoscopy specialist, Dr. Steptoe developed minimally invasive methods for retrieving oocytes, which became critical to the success of in vitro fertilization. In collaboration with Robert Edwards, Dr. Steptoe performed the first successful IVF procedure, which in 1978 resulted in the birth of Louise Brown, the world's first test-tube baby. Innovative surgical techniques proposed by Dr. Steptoe laid the foundation for current IVF protocols.

About the Authors

M. G. Gasanov
Sechenov University
Russian Federation

Mursal G. Gasanov

8 bldg. 2, Trubetskaya Str., Moscow 119048



R. A. Tuguscheva
Sechenov University
Russian Federation

Renata A. Tuguscheva

8 bldg. 2, Trubetskaya Str., Moscow 119048



M. U. Karapetyan
Sechenov University
Russian Federation

Mariya U. Karapetyan

8 bldg. 2, Trubetskaya Str., Moscow 119048



A. V. Vorobev
Sechenov University
Russian Federation

Alexander V. Vorobev - MD, PhD. Scopus Author ID: 57191966265. Wos ResearcherID: F-8804-2017. eLibrary SPIN-code: 5806-7062.

8 bldg. 2, Trubetskaya Str., Moscow 119048



References

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2. Edwards R., Steptoe P.C. A matter of life: the story of a medical breakthrough. London: Hutchinson Publishers, 1980. 188 p.

3. Steptoe P.C. Gynecological endoscopy – laparoscopy and culdoscopy. J Obstet Gynaecol Br Commonw. 1965;72:535–43. https://doi.org/10.1111/j.1471-0528.1965.tb00063.x.

4. Edwards R.G. Patrick Christopher Steptoe, C.B.E.: 9 June 1913 – 22 March 1988. Biogr Mem Fellows R Soc. 1996;42:435–52.

5. Steptoe P.C. Laparoscopy in gynaecology. Edinburgh: E & S Livingstone, 1967. 40 р.

6. Steptoe P.C. Historical aspects of the ethics of in vitro fertilization. Ann N Y Acad Sci. 1985;442:573–6. https://doi.org/10.1111/j.1749-6632.1985.tb37568.x.

7. Johnson M.H. Robert Edwards: the path to IVF. Reprod Biomed Online. 2011;23(2):245–62. https://doi.org/10.1016/j.rbmo.2011.04.010.

8. Steptoe P.C., Edwards R.G. Birth after the reimplantation of a human embryo. Lancet. 1978;2(8085):366. https://doi.org/10.1016/s0140-6736(78)92957-4.


Review

For citations:


Gasanov M.G., Tuguscheva R.A., Karapetyan M.U., Vorobev A.V. Patrick Christopher Steptoe: the surgeon without which there would be no IVF. Obstetrics, Gynecology and Reproduction. 2025;19(3):453-457. (In Russ.) https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.636

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)