From molecular medicine to artificial intelligence: prospects for reproductive medicine development

The journal brings together original research and analytical reviews devoted to the latest advances in obstetrics, gynecology, and reproductive medicine. The materials presented consider key issues of fertility preservation in cancer patients and the pathogenetic mechanisms of obstetric complications. They also cover innovative methods of diagnosing and treating gynecological diseases. Particular attention is paid to interdisciplinary aspects and personalized patient care, making use of the advances in molecular medicine and artificial intelligence. Articles combine fundamental research with clinical trials, offering new opportunities to enhance diagnostic and therapeutic strategies and contribute to the advancement of reproductive medicine as a multidisciplinary field.

1. Solovevskaya N.L., Pryanichnikov S.V. Age-related features of pregnancy in women in the conditions of the Kola North. [Osobennosti techeniya beremennosti u zhenshchin razlichnyh vozrastnyh grupp v usloviyah Kol'skogo Severa]. Obstetrics, Gynecology and Reproduction. 2025;19(3):327–340. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.576.

2. Melek M.I., Ignatko I.V., Timokhina E.V., Kuzmina T.E., Fedyunina I.A., Samoilova Yu.A., Alieva F.N., Grigoryan I.S., Podsekaeva S.A. Use of ophthalmic artery Doppler in preeclampsia prognosis and early diagnostics. [Ispol'zovanie doplerografii glaznyh arterij v prognozirovanii i rannej diagnostike preeklampsii]. Obstetrics, Gynecology and Reproduction. 2025;19(3):341–350. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.609.

3. Vorobev A.V., Bitsadze V.O., Khizroeva J.Kh., Solopova A.G., Mamchich D.M., Mun E.D., Blinov D.V., Gris J.-C., Elalamy I., Gerotziafas G., Van Dreden P., Makatsariya A.D. Hemostasis and metastasis: anticoagulants therapeutic potential in ovarian cancer. [Sistema gemostaza i metastazirovanie: terapevticheskij potencial antikoagulyantov pri rake yaichnikov]. Obstetrics, Gynecology and Reproduction. 2025;19(3):351–359. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.644.

4. Tormozova A.V., Erakaeva A.A., Ibadullaeva G.A., Galata A.S., Asinovskaya A.S., Kuzyura D.E., Efremova K.N., Chos V.M., Svarnik U.V., Dyachenko A.A., Mavlyutova A.N., Mukosiy L.A., Karpus Yu.S., Pirozhkova E.D., Albekova F.A., Sorokina L.E. Taxonomic diversity of the intestinal microbiome landscape and its clinical significance in recurrent pregnancy loss. [Taksonomicheskoe raznoobrazie mikrobiomnogo kishechnogo landshafta i ego klinicheskoe znachenie pri privychnom nevynashivanii beremennosti]. Obstetrics, Gynecology and Reproduction. 2025;19(3):360–368. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.620.

5. Syarief S.D.R., Ritonga M.A., Anwar R. The relationship between body mass index in adolescent pregnancy and preeclampsia at Hasan Sadikin Hospital 2019–2023. [Vzaimosvyaz' mezhdu indeksom massy tela pri podrostkovoj beremennosti i preeklampsiej v bol'nice Hasana Sadykina v 2019–2023 gg.]. Obstetrics, Gynecology and Reproduction. 2025;19(3):369–376. (In English). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.603.

6. Bitsadze V.О., Khizroeva J.Kh., Grandone Е., Gabidullina R.I., Tretyakova M.V., Makatsariya N.A., Gashimova N.R., Grigoreva K.N., Vorobev A.V., Lazarchuk A.V., Muravyova М.М., Krendeleva A.G., Polyakova T.E., Zainulina M.S., Kapanadze D.L., Yagubova F.E., Gris J.-C., Elalamy I., Gerotziafas G., Van Dreden P., Makatsariya A.D. Venous and arterial thromboses in ART programs: epidemiology and preventive strategies. [Venoznye i arterial'nye trombozy v programmah VRT: epidemiologiya i preventivnye strategii]. Obstetrics, Gynecology and Reproduction. 2025;19(3):377–388. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.656.

7. Zagidullina A.A., Dzhambulatova L.A., Shatueva M.A., Dongak T.B., Laubakh Y.S., Shakirova D.S., Golantsev A.S., Payzulaeva Kh.R., Yastrebova D.P., Aksenov A.M., Goncharova E.S., Ozhereleva M.A., Sargsyan D.G. Fertility preservation methods in the context of breast cancer treatment: real-life experience and prospects. [Metody sohraneniya fertil'nosti v kontekste lecheniya raka molochnoj zhelezy: real'nost' i perspektivy]. Obstetrics, Gynecology and Reproduction. 2025;19(3):389–407. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.607.

8. Dikke G.B., Makatsariya A.D., Ziganshin A.M., Shaikhieva E.A., Bitsadze V.O. Anatomy and function of closing muscle complex of the vagina in health and pelvic organ prolapse. [Anatomiya i funkciya myshechnogo kompleksa, zamykayushchego vlagalishche, v norme i pri prolapse tazovyh organov]. Obstetrics, Gynecology and Reproduction. 2025;19(3):408–422. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.615.

9. Lebina V.A., Shikhalakhova O.Kh., Kokhan A.A., Rashidov I.Yu., Tazhev K.A., Filippova A.V., Myshinskaya E.P., Symolkina Yu.V., Ibuev Yu.I., Mataeva A.A., Sirotenko A.N., Gabaraeva T.T., Askerova A.I. Opportunities and limitations of introducing artificial intelligence technologies into reproductive medicine. [Vozmozhnosti i ogranicheniya vnedreniya tekhnologij iskusstvennogo intellekta v reproduktivnuyu medicinu]. Obstetrics, Gynecology and Reproduction. 2025;19(3):423–442. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.591.

10. Antonova A.S., Khizroeva J.Kh., Kalashnikova I.S., Tretyakova M.V., Popyonova Yu.A., Kuneshko N.F., Fatkullina L.S. The complement system in pregnant women with severe preeclampsia. [Sistema komplementa u beremennyh s tyazheloj preeklampsiej]. Obstetrics, Gynecology and Reproduction. 2025;19(3):443–452. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.626.

11. Gasanov M.G., Tuguscheva R.A., Karapetyan M.U., Vorobev A.V. Patrick Christopher Steptoe: the surgeon without which there would be no IVF. [Patrik Kristofer Steptou: hirurg, bez kotorogo ne bylo by EKO]. Obstetrics, Gynecology and Reproduction. 2025;19(3):453–457. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2025.636.