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Generalized actinomycosis of the pelvic organs. Clinical case

https://doi.org/10.17749/2313-7347/ob.gyn.rep.2022.297

Abstract

Here, a clinical case of generalized actinomycosis of the pelvic organs occuring very rarely usually observed in immunocompromised patients is presented. Patient T. referred to the women's clinic with complaints of prolonged genital discharge, itching, burning, and occasional sub-fever. The patient had a history of prolonged hormonal immunosuppressive therapy. After a thorough examination, the patient was consulted by two oncologists. Preliminary diagnosis: suspicio cancer coli; suspicio cancer vaginae. In order to clarify the diagnosis, an in-hospital multifocal scalpel biopsy was performed. The biological material obtained was sent out for intravital pathological and anatomical examination; no signs of malignancy were found. To prevent complications during surgery, the patient underwent separate diagnostic scraping of the uterine cavity and cervical canal after repeated sanitation of the vagina and additional patient examination; hysteroscopy; vulval biopsy; colpocentesis. The final diagnosis was made after obtaining the results of in-surgery microbial culture on nutrient media. Active growth of actinomycetes was detected in the material obtained. The final clinical diagnosis was pelvic actinomycosis, generalized form. Patient T was discharged in satisfactory condition after antibacterial treatment according to the diagnosis for further under gynecologist observation at the women's clinic.

About the Authors

A. V. Kazakova
Samara State Medical University, Health Ministry of Russian Federation
Russian Federation

Anna V. Kazakova – МD, Dr Sci Med, Professor, Head of the Department of Obstetrics and Gynecology № 2 

89 Chapaevskaya Str., Samara 443099



O. I. Lineva
Samara State Medical University, Health Ministry of Russian Federation
Russian Federation

Olga I. Lineva – МD, Dr Sci Med, Professor, Honored Doctor of Russian Federation, Honorary Professor of the Department of Obstetrics and Gynecology № 2 

89 Chapaevskaya Str., Samara 443099



A. A. Trupakova
Samara State Medical University, Health Ministry of Russian Federation
Russian Federation

Anna A. Trupakova – МD, PhD Аpplicant, Department of Obstetrics and Gynecology № 2 

89 Chapaevskaya Str., Samara 443099



I. S. Kiyashko
Samara State Medical University, Health Ministry of Russian Federation; Pirogov Samara City Clinical Hospital № 1
Russian Federation

Irina S. Kiyashko – МD, PhD, Associate Professor, Department of Obstetrics and Gynecology № 2; Obstetrician-Gynecologist 

89 Chapaevskaya Str., Samara 443099;
80A Polevaya Str., Samara 443096



L. V. Kuznetsova
Pirogov Samara City Clinical Hospital № 1
Russian Federation

Liliya V. Kuznetsova – МD, PhD, Head of the Gynecological Department for Patients with Surgical and Purulent Pathologies № 19 

80A Polevaya Str., Samara 443096



V. A. Petyanova
Pirogov Samara City Clinical Hospital № 1
Russian Federation

Victoria A. Petyanova – МD, Obstetrician-Gynecologist, Deputy Chief Physician in Obstetrics and Gynecology 

80A Polevaya Str., Samara 443096



References

1. Zhuravel R.V. Complex treatment of actinomycosis of perianal and sacrococcygeal regions. [Kombinirovannoe lechenie aktinomikoza perianal'noj i krestcovo-kopchikovoj oblastej: Avtoref. dis. ... kand. med. nauk]. Stavropol', 2013. 18 p. (In Russ.).

2. Mirzabalaeva A.K., Kozlova O.P., Klimko N.N. Visceral actinomycosis. Tutorial. [Visceral'nyj aktinomikoz. Uchebnoe posobie]. SPb.: SZGMU im. I.I. Mechnikova, 2013. 48 p. (In Russ.).

3. Das K., Karateke F., Ozyazıcı S. et al. Unusual presentations of actinomycosis; anterior abdominal wall and appendix: report of three cases. Balkan Med J. 2013;30(3):315–7. https://doi.org/10.5152/balkanmedj.2012.377.

4. Bunkov K.V., Kozlov D.V., Nikiforovskaya E.N., Fofonova I.Yu. The gynecological sepsis caused by actinomycetes (case report). [Ginekologicheskij sepsis, vyzvannyj aktinomicetami (opisanie sluchaya)]. Problemy reprodukcii. 2015;21(4):23–6. (In Russ.).

5. Kozlova O.P., Mirzabalaeva A.K., Klimko N.N. Actinomycosis of abdominal cavity and small pelvis. [Aktinomikoz organov bryushnoj polosti i malogo taza]. Problemy medicinskoj mikologii. 2014;16(3):44–50. (In Russ.).

6. Tarasenko V.S., Kislov M.A., Svoykin S.K. A clinical case of actinomycosis of the abdominal wall and pelvic organs. [Klinicheskij sluchaj aktinomikoza bryushnoj stenki i organov malogo taza]. Rany i ranevye infekcii. Zhurnal imeni professora B.M. Kostyuchyonka. 2015;2(4):47–51. (In Russ.).

7. Slukhanchuk E.V., Tyan A.G., Bedzhanyan A.L. et al. Angiomyxoma of the pelvis in women. Clinical cases. Obstetrics, Gynecology and Reproduction. 2021;15(5):617–26. (In Russ.). https://doi.org/10.17749/2313-7347/ob.gyn.rep.2021.234

8. Kozlova O.P., Chernopyatova R.M., Mitrofanov V.S. Case of successful treatment of thoracic actinomycosis. [Sluchaj uspeshnogo lecheniya torakal'nogo aktinomikoza]. Problemy medicinskoj mikologii. 2013;15(2):35–9. (In Russ.).

9. Kozlova O.P., Mirzabalaeva A.K. Actinomycosis of inside woman's genitals. [Aktinomikoz vnutrennih reproduktivnyj organov u zhenshchin]. Zhurnal nauchnyh statej «Zdorov'e i obrazovanie v XXI veke». 2014;16(4):109–10. (In Russ.).

10. Kozlova O.P., Sheviakov M.A., Klimko N.N. Features of intestinal actinomycosis. [Osobennosti aktinomikoza kishechnika]. Eksperimental'naya i klinicheskaya gastroenterologiya. 2017;11(147):55–9. (In Russ.).

11. Batirel A., Arslan F., Keser S.H. et al. Primary hepatic actinomycosis mimicking a tumor (inflammatory pseudotumor): Case report and literature review. J Microbiol Infect Dis. 2015;5(2):79–84. https://doi.org/10.5799/ahinjs.02.2015.02.0181.

12. Gavrilov Ya.Ya., Tupikin K.A., Andreitseva O.I., Vishnevsky V.A. Abdominal actinomycosis in patients with liver lesions: experience of the A.V. Vishnevsky. XXIII International Congress of the Association of Hepatopancreatobiliary Surgeons of the CIS countries "Actual problems of hepatopancreatobiliary surgery": abstracts. [Abdominal'nyj aktinomikoz u pacientov s porazheniyami pecheni: opyt Instituta hirurgii imeni A.V. Vishnevskogo. HHIII Mezhdunarodnyj kongress Associacii gepatopankreatobiliarnyh hirurgov stran SNG «Aktual'nye problemy gepatopankreatobiliarnoj hirurgii»: tezisy dokladov]. Minsk, 2016. 26–8. (In Russ.).

13. Tholozan A.-S., Terzibachian J.J., Bourtembourg A. et al. Secondary psoas actinomycosis: a complication of an intra-uterine contraceptive device. Gynecol Obstet Fertil. 2013;41(3):190–2. [Article in French]. https://doi.org/10.1016/j.gyobfe.2012.09.028.

14. Choi M.-M., Baek J.H., Lee J.N. et al. Clinical features of abdominopelvic actinomycosis: report of twenty cases and literature review. Yonsei Med J. 2009;50(4):555–9. https://doi.org/10.3349/ymj.2009.50.4.555.

15. Triantopoulou C., der Molen A.V., Es A.C., Giannila M. Abdominopelvic actinomycosis: spectrum of imaging findings and common mimickers. Acta Radiol Short Rep. 2014;3(2):2047981614524570. https://doi.org/10.1177/2047981614524570.

16. Evsyukova E.V., Strelnikov A.A., Obrezan A.G., Rodionova D.V. Abdominal actinomycosis: diagnostic difficulties (clinical analysis at the Department of Hospital Therapy). [Abdominal'nyj aktinomikoz: trudnosti diagnostiki (klinicheskij razbor na kafedre gospital'noj terapii)]. Medicina. XXI vek. 2009;(14):75–80. (In Russ.).

17. Сolon-Candelaria M.M., Duharte-Vidaurre L., Sanchez- Sergenton C. et al. An unusual presentation of actinomycosis in a young woman, after surgery. Bol Asoc Med P R. 2005;97(3Pt2):209–13.

18. Oura H., Aikawa H., Handa M. et al. Pulmonary actinomycosis developing diffuse phregmone after pneumonectomy. Kyobu Geka. 2006;59(5):359–64. [Article in Japanese].

19. Olivera-Reynada A., Calzada-Ramos M.A., Espinoza-Guerrero X. et al. Abdominal actinomycosis: report of three cases. Cir Cir. 2005;73(1):47–50. [Article in Spanish].

20. Pagliani L., Campi L., Cavallini G.M. Orbital actinomycosis associated with painful ophthalmoplegia. Actinomycosis of the orbit. Ophthalmologica. 2006;220(3):201–5. https://doi.org/10.1159/000091767.

21. Louerat C., Depagne C., Nesme P., Biron F., Guerin J.C. Disseminated actinomycosis. Rev Mal Respir. 2005;22(3):473–6. [Article in French]. https://doi.org/10.1016/s0761-8425(05)85575-5.


Review

For citations:


Kazakova A.V., Lineva O.I., Trupakova A.A., Kiyashko I.S., Kuznetsova L.V., Petyanova V.A. Generalized actinomycosis of the pelvic organs. Clinical case. Obstetrics, Gynecology and Reproduction. 2022;16(3):317-323. (In Russ.) https://doi.org/10.17749/2313-7347/ob.gyn.rep.2022.297

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)