Vol 7, No 4 (2013)
ОRIGINAL ARTICLES
6-10 427
Abstract
One of the dominant clinical symptoms of adenomyosis is chronic pelvic pain . Chronic pelvic pain is recurrent or persistent pain that bothers patient less than 6 months. The aim of the study was to determine the clinical informativeness use of oncological markers CA-125 and NOT-4 in blood serum of women with pelvic pain caused by
adenomyosis. In the present study included 63 patients adenomyosis – as a core group, and 30 apparently healthy women of reproductive age as a comparison group. Indicators CA-125 were higher in patients in the second subgroup with moderately severe pain syndrome, and the average at the time of treatment amounted to 45-63 U/ml, P<0.001), but on the second day of the menstrual cycle indicators again increased and averaged 54-70 U/ml ,and also significantly (P<0.001) decreased in the study after the end of the regular menstruation( 1st-2nd dry day after menstruation in the framework of the first phase of the menstrual cycle and averaged 42-60 U/ml compared with the comparison group apparently healthy women-8.9 IU/ml Conclusion , the evidence suggests that women with pelvic pain syndrome adenomyosis is the place to co-proliferative endometrial pathology. And in these cases increasyse the sensitivity of the above serological markers. The use of two markers (NOT-4 and CA-125) has a more accurate diagnostic value to identify the process of malignization in the reproductive organs, and it is important for differential diagnosis of hyperplastic processes, and for early diagnosis of endometrial adenocarcinoma.
adenomyosis. In the present study included 63 patients adenomyosis – as a core group, and 30 apparently healthy women of reproductive age as a comparison group. Indicators CA-125 were higher in patients in the second subgroup with moderately severe pain syndrome, and the average at the time of treatment amounted to 45-63 U/ml, P<0.001), but on the second day of the menstrual cycle indicators again increased and averaged 54-70 U/ml ,and also significantly (P<0.001) decreased in the study after the end of the regular menstruation( 1st-2nd dry day after menstruation in the framework of the first phase of the menstrual cycle and averaged 42-60 U/ml compared with the comparison group apparently healthy women-8.9 IU/ml Conclusion , the evidence suggests that women with pelvic pain syndrome adenomyosis is the place to co-proliferative endometrial pathology. And in these cases increasyse the sensitivity of the above serological markers. The use of two markers (NOT-4 and CA-125) has a more accurate diagnostic value to identify the process of malignization in the reproductive organs, and it is important for differential diagnosis of hyperplastic processes, and for early diagnosis of endometrial adenocarcinoma.
Yu. Yu. Tabakman,
I. B. Manukhin,
A. G. Solopova,
A. A. Kanibolotsky,
A. Kh. Bishtavi,
O. A. Gornykh,
V. V. Samoylenko,
V. N. Gulieva,
Kh. T. Gogoladze,
N. G. Chikovani
11-14 454
Abstract
Differencial diagnostics of simple, complex and atypical hyperplasia and endometrial cancer(SEH, CEH, AEH, EC) presents a number of difficulties which often lead to a different interpretation of the same histologic samples. The
aim: to evaluate the ability of computer morphometry(CM) used in case of endometrial hyperplasia. Material: 36 patients, including 12 patients with SEH, 11 patients with CEH, 7 patients with AEH and 5 patients with EC. Method of ImaScope
Color morphometric programme. Conclusion: morphometric changes that occur in case of endometrial hyperplasia expressed in quantitative terms are more varied than their schematic definition in modern classification which in its turn may be the cause of the discrepanies in diagnoses.
aim: to evaluate the ability of computer morphometry(CM) used in case of endometrial hyperplasia. Material: 36 patients, including 12 patients with SEH, 11 patients with CEH, 7 patients with AEH and 5 patients with EC. Method of ImaScope
Color morphometric programme. Conclusion: morphometric changes that occur in case of endometrial hyperplasia expressed in quantitative terms are more varied than their schematic definition in modern classification which in its turn may be the cause of the discrepanies in diagnoses.
REVIEW ARTICLE
20-24 466
Abstract
In the literature review presents the status of the study of the problem of bacterial vaginosis during and outside of pregnancy, provides criteria of diagnostics and differential diagnostics, standards of treatment and prevention opportunities.
25-31 368
Abstract
An analysis of literature data is given regarding the role of different types of therapy used for the treatment of threatened preterm labor including the efficacy and safety of such treatments.
32-34 521
Abstract
The problem of genital tuberculosis is very actual. Special attention deserves an increase the number of TB patients, aged 25-34 years – the age of peak fertility. The period from the beginning of the disease to establish a correct diagnosis is often reaches 5-20 years. Many years the patient can have only one complaint – infertility. The relevance of genital tuberculosis modern diagnostics is determined by the mismatch objective of increasing the prevalence of pulmonary tuberculosis and subjective low prevalence of urogenital tuberculosis associated with the complexity of its detection and treatment outcomes. Among the modern methods of immunodiagnostics tuberculosis, great importance
is the identification of specific antibodies to Mycobacterium tuberculosis in the peripheral blood by enzyme immunoassay and immunochromatographic rapid test.
is the identification of specific antibodies to Mycobacterium tuberculosis in the peripheral blood by enzyme immunoassay and immunochromatographic rapid test.
35-43 632
Abstract
Metabolic syndrome is commonly found among women of reproductive age and represents a risk factor for various pregnancy complications. The presence of genetically determined hypofibrinolysis in women with metabolic syndrome, along with other forms of thrombophilia, determines the implantation failure and abnormalities in trophoblast
invasion and placentation. Subsequently, this may cause the fetal loss syndrome and other pregnancy complications.
invasion and placentation. Subsequently, this may cause the fetal loss syndrome and other pregnancy complications.
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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)
ISSN 2500-3194 (Online)