BASIC PRINCIPLES OF TREATMENT OF ANEMIA AND THROMBOPHILIC STATUS VIN PREGNANT AND POSTPARTUM WOMEN
Abstract
The article gives an overview of the forms of anemia, the impact of anemia in pregnancy and obstetric complications. Overwieved the main approaches to the treatment of anemia during pregnancy. A comparative analysis of the use of drugs of ferrous and ferric iron. Discussion of the possibilities given relief thrombophilic conditions in combination with anemia. Formulated the main principles of survey of pregnant women with anemia, as well as the treatment of anemia in pregnant and postpartum women.
About the Author
E. S. Egorova
First Moscow State Medical Sechenov University of the Ministry of Health Russian Federation
Russian Federation
Russian Federation
References
1. Akin'shina S.V., Makatsariya A.D., Bitsadze V.O. Akusherstvo, ginekologiya i reproduktsiya. 2014; 1: 15-25.
2. Gorokhovskaya G.N., Zimaeva Yu.O., Yuzhaninova O.V. i dr. Trudnyi patsient. 2007; 9: 35-41.
3. Demikhov V.G. Anemiya beremennykh: differentsial’naya diagnostika i patogeneticheskoe obosnovanie terapii. Doct, Diss. (Anemia in pregnancy: differential diagnosis and therapy pathogenetic substantiation). Dr. diss. Ryazan’. 2003.
4. Kashezheva A.Z., V.S. Efimov. Tromboz, gemostaz, reologiya. 2001; 3: 14-18.
5. Konovodova E.N., Burlev V.A. Akusherstvo I ginekologiya. 2012; 1: 137-142.
6. Konovodova E.N., Burlev V.A., Tyutyunnik V.L. i dr. Voprosy ginekologii, akusherstva i perinatologii. 2011; 10 (5): 26-30.
7. Lakotko N.N. Meditsinskaya panorama. 2007; 5 (73): 20-22.
8. Makatsariya A.D., Bitsadze V.O. Thrombophilia and antithrombotic therapy in obstetric practice [Trombofilii i protivotromboticheskaya terapiya v akusherskoi praktike]. Moscow. 2003; 185-188, 798-812.
9. Makatsariya A.D., Bitsadze V.O., Baimuradova S.M.,Perederyaeva E.B., Pshenichnikova T.B., Khizroeva D.Kh., Donina E.V., Akin’shina S.V. Prevention of recurrent complications of pregnancy in terms of thrombophilia (fetal loss syndrome, gestational toxicosis, premature detachment of the placenta, thrombosis and thromboembolism). Guidance for doctors [Profilaktika povtornykh oslozhnenii beremennosti v usloviyakh trombofilii (sindrom poteri ploda, gestozy, prezhdevremennaya otsloika normal’no raspolozhennoi platsenty, trombozy I tromboembolii). Rukovodstvo dlya vrachei]. Moscow. 2008; 152 s.
10. Nikitin E.N., Dolgova O.N., Shishkina A.A., Yushkova M.V., Manakov V.A. Prakticheskaya meditsina. 2011; 50: 93.
11. Ordzhonikidze N.V., Sokolova M.Yu., Suleimanova I.G. Problemy reproduktsii. 2005; 6.
12. Petukhov V.S. Okhrana materinstva i detstva. 2009; 1-13: 68-77.
13. Protopopova T.A. RMZh. 2012; 17: 862-867.
14. Savel’eva G.M., V.S. Efimov, A.Z. Kashezheva. Akusherstvo i ginekologiya. 2000; 3: 3-5.
15. Serov V.N. Klinicheskaya farmakologiya I terapiya. 2005; 14 (2): 78-83.
16. Хух Р,. Брейман К. Анемия во время беременности и в послеродовом периоде. М. 2007; 73 с.
17. Barroso F., Allard S., Kahan B.C. et al. Prevalence of maternal anaemia and its predictors: a multi-centre study. Eur. J. Obstet. Gynecol. Reprod. Biol. 2011; 2: 179-186.
18. Bencaiova G., von Mandach U., Zimmermann R. Iron prophylaxis in pregnancy: intravenous route versus oral route. Eur. J. Obstet. Gynecol. Reprod. Biol. 2009; 144 (2): 135-139.
19. Bencaiova G., Burkhardt T., Breymann C. Anemia -prevalence and risk factors in pregnancy. Eur. J. Intern. Med. 2012; 23 (6): 529-533.
20. Breymann C., Honegger C., Holzgreve W., Surbek D. Diagnosis and treatment of irondeficiency anaemia during pregnancy and postpartum. Arch. Gynecol. Obstet. 2010; 282 (5): 577-580.
21. Bonnar J., Green R., Norris L. Inherited thrombophilia and pregnancy: the obstetric perspective. Semin. Thromb. Hemost. 2008; 24 (1): 49-53.
22. Coumans A.B., Huijgens P.C., Jakobs C., Schats R., de-Vries J.I., van-Pampus M.G., Dekker G.A. Haemostatic and metabolic abnormalities in women with unexplained recurrent abortion. Hum.Reprod. 2009; 14 (1): 211-214.
23. Casanueva E., Viteri F.E. Iron and Oxidative Stress in Pregnancy. J. Nutr. May 2003; 133: 1700-1708.
24. Critchley J, Bates I.. Haemoglobin colour scale for anaemia diagnosis where there is no laboratory: a systematic review. Int. J. Epidemiol. 2005; 34: 1425-1434.
25. Kochhar P.K., Kaundal A., Ghosh P. Intravenous iron sucrose versus oral iron in treatment of iron deficiency anemia in pregnancy: A randomized clinical trial. J. Obstet. Gynaecol. Res. 2012; 26: 1-7.
26. Pasricha S.R., Flecknoe-Brown S.C., Allen K.J. et al. Diagnosis and management of iron deficiency anaemia: a clinical update. Med. J. Aust. 2010; 193 (9): 525-532.
27. Powers R.W., Evans R.W., Majors A.K., Ojimba J.I., Ness R.B., Crombleholme W.R., Roberts J.M. Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation. Am. J. Obstet.Gynecol. 2005; 179 (6 Pt 1): 1605-1511.
28. Shao J., Lou J, Rao R. et al. Maternal serum ferritin concentration is positively associated with newborn iron stores in women with low ferritin status in late pregnancy. J. Nutr. 2012; 142 (11): 2004-2009. 29. V. De Stefano, G.Finazzi, P.M.Mannucci. Inherited thrombophilia: Pathogenesis, clinical syndromes and management. Blood. 2006; 87 (9): 3531-3544.
29. Van-Pampus M.G., Dekker G.A., Wolf H., Huijgens P.C., Koopman M.M., von-Blomberg B.M., Buller H.R. High prevalence of hemostatic abnormalities in women with a history of severe preeclampsia. Am. J. Obstet. Gynecol. 2004; 180 (5): 1146-1150.
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For citations:
Egorova E.S. BASIC PRINCIPLES OF TREATMENT OF ANEMIA AND THROMBOPHILIC STATUS VIN PREGNANT AND POSTPARTUM WOMEN. Obstetrics, Gynecology and Reproduction. 2014;8(3):65-70. (In Russ.)
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