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Regarding the evidence-based use of micronized progesterone

https://doi.org/10.17749/2313-7347/ob.gyn.rep.2020.171

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Abstract

An issue of habitual miscarriage poses a high social importance especially during COVID-19 pandemic. Meanwhile, healthcareworkers faced a mass media campaign against using micronized progesterone upon habitual miscarriage, which, as viewed by us, displays signs of prejudiced data manipulation and may disorient practitioners. In this Letter we provide objective information on accumulated data regarding gestagenes efficacy and safety. We invoke healthcare professionals to make decisions deserving independent primary source trust presented by original scientific papers published in peer-reviewed journals, clinical recommendations proposed by professional medical communities as well as treatment standards and protocols.

About the Authors

A. D. Makatsariya
Sechenov University
Russian Federation

Alexander D. Makatsariya - MD, Dr Sci Med, Professor, Academician of RAS, Head of the Department of Obstetrics and Gynecology, N. F. Filatov Clinical Institute of Children’s Health, Vice-President of the Russian Society of Obstetricians and Gynecologists

62 Str. Zemlyanoi Val., Moscow 109004

Scopus Author ID: 6602363216

Researcher ID: M-5660-2016



G. C. Di Renzo
Sechenov University; Center for Prenatal and Reproductive Medicine, University of Perugia
Russian Federation

Gian Carlo Di Renzo - MD, Professor, Department of Obstetrics and Gynecology, Director of the Center for Prenatal and Reproductive Medicine,Honorary Secretary General of the International Federation of Gynecology and Obstetrics (FIGO)

62 Str. Zemlyanoi Val., Moscow 109004

Italy, Umbria, Perugia, Piazza Italia

Scopus Author ID: 7103191096

Researcher ID: P-3819-2017



G. Rizzo
Tor Vergata University of Rome
Italy

Giuseppe Rizzo - MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology, N. F. Filatov Clinical Institute of Children’s Health, Sechenov University

18 Via Orazio Raimondo, Rome 00173, Italy

Author ID: 7102724281. Researcher ID: G-8234-2018



V. O. Bitsadze
Sechenov University
Russian Federation

Viktoria O. Bitsadze - MD, Dr Sci Med, Professor of RAS, Professor, Department of Obstetrics and Gynecology, N. F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val., Moscow 109004

Scopus Author ID: 6506003478

Researcher ID: F-8409-2017



J. Kh. Khizroeva
Sechenov University
Russian Federation

Jamilya Kh. Khizroeva - MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology, N. F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val., Moscow 109004

Scopus Author ID: 57194547147

Researcher ID: F-8384-2017



D. V. Blinov
Institute for Preventive and Social Medicine; Lapino Clinic Hospital, MD Medical Group; Moscow Haass Medical - Social Institute
Russian Federation

Dmitry V. Blinov - MD, PhD, MBA, Head of Medical and Scientific Affairs, Institute of Preventive and Social Medicine, Neurologist, Faculty Member, Department of Neurology, Psychiatry and Narcology

4–10 Sadovaya-Triumfalnaya Str., Moscow 127006

1st Uspenskoye Highway

5, 1–1a 2nd Brestskaya Str., Moscow 123056

Researcher ID: E-8906-2017

RSCI: 9779-8290



E. I. Vovk
Moscow State University of Medicine and Dentistry named after А. I. Evdokimov, Health Ministry of Russian Federation
Russian Federation

Elena I. Vovk - MD, PhD, Clinical Pharmacologist, Associate Professor, Department of Therapy

20 bldg. 1, Delegatskaya Str., Moscow 127473



I. E. Govorov
Almazov National Medical Research Centre, Health Ministry of Russian Federation
Russian Federation

Igor E. Govorov - MD, PhD, Obstetrician-Gynecologist, Research Laboratory of Operative Gynecology, Institute of Perinatology and Pediatrics

2 Akkuratova Str., Saint Petersburg 197341

Scopus Author ID: 57188586021

Researcher ID: P-1257-2015



D. L. Guryev
Yaroslavl State Medical University, Health Ministry of Russian Federation; Yaroslavl Regional Perinatal Center
Russian Federation

Dmitry L. Guryev - MD, PhD, Associate Professor, Department of Obstetrics and Gynecology, Chief Obstetrician

5 Revolutsionnaya Str., Yaroslavl 150000

31B Tutaevskoe Highway, Yaroslavl 150042



G. B. Dikke
Academy of Medical Education named by F. I. Inozemtsev
Russian Federation

Galina B. Dikke - MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology with the course of reproductive medicine, Expert of the Russian Academy of Sciences, Honored Worker of Science and Education

8 liter B, Ruzovskaya Str., Saint Petersburg 190013

 

 



M. S. Zainulina
I.P. Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian Federation; V.F. Snegirev Maternity Hospital № 6 and City Obstetric Hematological Center
Russian Federation

Marina S. Zainulina - MD, Dr Sci Med, Professor, Department of Obstetrics, Gynecology and Reproductive Medicine, Head Physician

6/8 Lev Tolstoy Str., Saint Petersburg 197022

5 Mayakovskogo Str., Saint Petersburg 192014

Scopus Author ID: 37076359000

Researcher ID: B-5746-2018



N. S. Zakharova
City Clinical Hospital named after V. V. Vinogradov, Moscow Healthcare Department
Russian Federation

Natalya S. Zakharova - MD, Obstetrician-Gynecologist, Department of Pregnancy Pathology

61 Vavilova Str., 117292 Moscow



V. V. Kovalev
Ural State Medical University, Health Ministry of Russian Federation
Russian Federation

Vladislav V. Kovalev - MD, Dr Sci Med, Professor, Head of the Department of Obstetrics and Gynecology

3 Repin Str., Ekaterinburg 620219

Researcher ID: N-5315-2015



E. V. Komlichenko
Almazov National Medical Research Centre, Health Ministry of Russian Federation
Russian Federation

Eduard V. Komlichenko - MD, Dr Sci Med, Deputy Director of the Institute of Perinatology and Pediatrics

2 Akkuratova Str., Saint Petersburg 197341

Researcher ID: N-5315-2015



V. A. Kramarskiy
Irkutsk State Medical Academy of Postgraduate Education - Branch Campus of Russian Medical Academy of Continuing Professional Education, Health Ministry of Russian Federation
Russian Federation

Vladimir A. Kramarskiy - MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology

100 Yubileiny microdistrict, Irkutsk 664049



A. B. Loginov
V.F. Snegirev Maternity Hospital № 6 and City Obstetric Hematological Center
Russian Federation

Alexander B. Loginov - MD, PhD, Deputy Head Physician for Clinical Expert Work

5 Mayakovskogo Str., Saint Petersburg 192014



L. I. Maltseva
Kazan State Medical Academy - Branch of Russian Medical Academy of Continuing Professional Education, Health Ministry of Russian Federation
Russian Federation

Larisa I. Maltseva - MD, Dr Sci Med, Professor of the Department of Obstetrics and Gynecology

36, Butlerova Str., Kazan 420015



V. B. Nemirovskiy
Maternity Hospital № 1 - Branch of City Clinical Hospital № 67 named after L. A. Vorokhobov, Moscow Healthcare Department
Russian Federation

Vyacheslav B. Nemirovskiy - MD, PhD, Head of Maternity Hospital № 1

2/44 Salyama Adilya Str., Moscow 123423



D. A. Ponomarev
Maternity Hospital № 4 - Branch of City Clinical Hospital named after V. V. Vinogradov, Moscow Healthcare Department
Russian Federation

Dmitry A. Ponomarev - MD

3 Novatorov Str., Moscow 117421



E. B. Rudakova
State Scientific Center of the Russian Federation - Federal Medical Biophysical Center named after A. I. Burnazyan, Federal Medical and Biological Agency of Russia
Russian Federation

Elena B. Rudakova - MD, Dr Sci Med, Professor, Department of Obstetrics, Gynecology and Perinatology, Obstetrician-Gynecologist, Honored Doctor of the Russian Federation

46 Zhivopisnaya Str., Moscow 1231982



N. V. Samburova
Sechenov University
Russian Federation

Natalia V. Samburova - MD, PhD, Associate Professor, Department of Pathophysiology, Institute of Clinical Medicine

62 Str. Zemlyanoi Val., Moscow 109004



O. F. Serova
Moscow Regional Perinatal Center
Russian Federation

Olga F. Serova - MD, Dr Sci Med, Professor, Head Physician, Chief External Expert of Health Ministry of Moscow Region

12 Entuziastov Highway, Balashikha, Moscow Region 143900

 



F. K. Tetelyutina
Izhevsk State Medical Academy, Health Ministry of Russian Federation
Russian Federation

Faina K. Tetelyutina - MD, Dr Sci Med, Professor, Head of Department of Obstetrics and Gynecology

281 Kommunarov Str., Izhevsk 426034

 



M. V. Tretyakova
«Medical Center» LLC
Russian Federation

Maria V. Tretyakova - MD, PhD, Obstetrician-Gynecologis

15/1 Timura Frunze Str., Moscow 119021



J. Yu. Ungiadze
Shota Rustaveli Batumi State University; Iris Borchashvili Health Center Medina
Georgia

Jumber Yu. Ungiadze - MD, Dr Sci Med, Professor, Faculty of Medicine, Director

35 Ninoshvili Str., Batumi, 6010, Georgia

237 Fridon Khalvashi Avenue, Batumi 6004, Georgia



V. I. Tsibizova
Almazov National Medical Research Centre, Health Ministry of Russian Federation
Russian Federation

Valentina I. Tsibizova - MD, Departments of Functional and Ultrasound Diagnostics

2 Akkuratova Str., Saint Petersburg 197341



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For citation:


Makatsariya A.D., Di Renzo G.C., Rizzo G., Bitsadze V.O., Khizroeva J.K., Blinov D.V., Vovk E.I., Govorov I.E., Guryev D.L., Dikke G.B., Zainulina M.S., Zakharova N.S., Kovalev V.V., Komlichenko E.V., Kramarskiy V.A., Loginov A.B., Maltseva L.I., Nemirovskiy V.B., Ponomarev D.A., Rudakova E.B., Samburova N.V., Serova O.F., Tetelyutina F.K., Tretyakova M.V., Ungiadze J.Yu., Tsibizova V.I. Regarding the evidence-based use of micronized progesterone. Obstetrics, Gynecology and Reproduction. 2020;14(3):374-383. (In Russ.) https://doi.org/10.17749/2313-7347/ob.gyn.rep.2020.171

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)