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On the pathogenesis of thromboses in antiphospholipid syndrome

https://doi.org/10.17749/2313-7347.2018.12.3.072-078

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Abstract

Antiphospholipid antibodies (AFA) are a heterogeneous group of autoantibodies produced humans under various pathological conditions; the main one of those is the antiphospholipid syndrome. AFA cause a number of serious complications, such as thrombosis, pathology of pregnancy and childbirth, multisystem damage to organs and tissues. Thrombosis caused by AFA can develop both in the venous and arterial circulation, and are characterized by high mortality and morbidity rates.

About the Authors

T. A. Sukontseva
I.P. Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian Federation
Russian Federation
Sukontseva Tatyana Alexandrovna – 5th year Medical Student, Faculty of General and Preventive Medicine, I.P. Pavlov FSPb SMU HM of RF. Теl: +7(981)8581062.
6/8, ul. L'va Tolstogo, Saint Petersburg, 197022, Russia


O. Yu. Kaplina
I.M. Sechenov First Moscow State Medical University, Health Ministry of Russian Federation
Russian Federation
Kaplina Olga Yurievna – Research Associate, Department of Obstetrics and Gynecology No 2, I.M. Sechenov First MSMU HM of RF.
8, str. 2, ul. Trubetskaya, Moscow, 119991, Russia


For citation:


Sukontseva T.A., Kaplina O.Y. On the pathogenesis of thromboses in antiphospholipid syndrome. Obstetrics, Gynecology and Reproduction. 2018;12(3):72-78. (In Russ.) https://doi.org/10.17749/2313-7347.2018.12.3.072-078

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)