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PLACENTAL INSUFFICIENCY IN COMPLICATED PREGNANCY AND POSSIBILITY OF TREATMENT WITH DIPYRIDAMOLE

https://doi.org/10.17749/2313-7347.2016.10.4.072-082

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Abstract

Placental insufficiency is an acute or chronic process leading to progressive deterioration in placental function and a decrease in transplacental transfer of oxygen and nutrients to the fetus. The resulting fetal hypoxemia is hypoxia and reduction in fetal growth with abnormal neurodevelopment during childhood as outcome. Current approaches in classification, diagnostics and management of placental insufficiency in women with complicated pregnancy are presented in the review article. Treatment of placental insufficiency includes antiplatelet agents, low molecular weight heparins and vitamin and mineral supplementation. Dipyridamole is most preferred antiplatelet agents that could be prescribed in I-III trimesters. Proper preconception can help to prevent placental insufficiency in women with respective risk-factors.

About the Authors

A. D. Makatsariya
FSBEI HE I.M. Sechenov First MSMU MOH Russia
Russian Federation

MD, corresponding member of the Russian Academy of Sciences, Professor, Head of the Department of Obstetrics and Gynecology, Faculty of Medical and Preventive,

ul. Trubetskaya, 8, str. 2, Moskva, 119048



V. O. Bitsadze
FSBEI HE I.M. Sechenov First MSMU MOH Russia
Russian Federation

MD, Professor, Department of Obstetrics and Gynecology,

ul. Trubetskaya, 8-2, Moskva, 119048



D. Kh. Khizroeva
FSBEI HE I.M. Sechenov First MSMU MOH Russia
Russian Federation

MD, Professor of the Department of Obstetrics and Gynecology, Faculty of Medical and Preventive,

ul. Zemlyanoi Val, 62-1, 109004, Moscow



I. V. Khamani
FSBEI HE I.M. Sechenov First MSMU MOH Russia
Russian Federation

post graduate student of the Department of Obstetrics and Gynecology, Faculty of Medical and preventive,

ul. Trubetskaya, 8, str. 2, Moscow, 119048



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For citation:


Makatsariya A.D., Bitsadze V.O., Khizroeva D.K., Khamani I.V. PLACENTAL INSUFFICIENCY IN COMPLICATED PREGNANCY AND POSSIBILITY OF TREATMENT WITH DIPYRIDAMOLE. Obstetrics, Gynecology and Reproduction. 2016;10(4):72-82. (In Russ.) https://doi.org/10.17749/2313-7347.2016.10.4.072-082

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)