ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY
Abstract
and to develop pathogenetically substantiated treatment regimen. Materials and Methods: a prospective trial of 96 fertile women with abnormal uterine bleeding concomitant extragenital pathology. All patients received a standard hemostatic
therapy, 48 women additionally administered melatonin (Group 1), and 48 women received standard therapy without melatonin (group 2). 23 patients without any gynecologic and extragenital pathology comprised Group 3 (control group). Results: melatonin usage during treatment of uterine bleeding in fertile women with combined extragenital pathology: to increasing levels of cortisol, which indicates the possibility of a more rapid formation of the adaptation syndrome; stabilizes the endogenous melatonin; normalizes the ratio of estrogen and progesterone levels, optimizing hormonal balance, regardless of the original background and level of the breach, and thus increases the efficiency of the treatment of uterine bleeding, which is important for practical medicine.
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Review
For citations:
Tananakina E.N. ЕFFECTIVENESS OF THE DRUG MELATONIN WOMEN OF REPRODUCTIVE AGE WITH ABNORMAL UTERINE BLEEDING AND COMBINED EXTRAGENITAL PATHOLOGY. Obstetrics, Gynecology and Reproduction. 2014;8(3):31-38. (In Russ.)

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