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Phytoestrogens in treatment of climacteric syndrome as an alternative to menopausal hormone therapy

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Here we review Russia-wide and international publications released over the last 5 years dedicated to phytoestrogens used in treatment of climacteric syndrome. Effects of isoflavones as the most examined agents are discussed acting on vasomotor, cognitive, psychological, urogenital and sexual symptoms as well as on the cardiovascular system, bones, and metabolic age-related changes. Despite obtaining controversial data resulting from the analysis, it may be concluded phytoestrogens hold promise as an alternative to menopausal hormone therapy. It is reasonable to conduct further extensive studies to evaluate efficacy and safety of using plant-derived compounds in postmenopausal women.

About the Authors

M. I. Mazitova
Kazan State Medical Academy – Branch of Russian Medical Academy of Continuing Professional Education, Health Ministry of Russian Federation
Russian Federation

Madina I. Mazitova – MD, Dr Sci Med, Professor, Professor, Department of Obstetrics and Gynecology

36, Butlerova Str., Kazan 420015

I. R. Talipova
Medical and Diagnostic Center "Razumed" LLC
Russian Federation

Ilseiar R.Talipova – MD, Obstetrician-Gynecologist

53a Yulius Fuchik Str., Kazan 420138

R. R. Mardieva
Kazan State Medical Academy – Branch of Russian Medical Academy of Continuing Professional Education, Health Ministry of Russian Federation; City Clinical Hospital № 7
Russian Federation

Reseda R. Mardieva – MD, Assistant, Department of Obstetrics and Gynecology;

36, Butlerova Str., Kazan 420015;

54 Marshal Chuikov Str., Kazan 420103


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For citation:

Mazitova M.I., Talipova I.R., Mardieva R.R. Phytoestrogens in treatment of climacteric syndrome as an alternative to menopausal hormone therapy. Obstetrics, Gynecology and Reproduction. 2020;14(6):685-693. (In Russ.)

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