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The aim of this research was studies character of clinical course of gestation and immunological markers in pregnant women with gestational hypertension and pre-eclampsia. In150 pregnant women with gestational hypertension and pre-eclampsia (basic group I) and 50 healthy pregnant women at the same gestational period (control group) was studies clinical course of gestation and plazma levels of twelve natural autoantibodies. The levels of autoantibodies throughout pregnancy were analyzed with an ELISA assay. First gestational trimester with hypertensive disorders accompanied with different complications in 62% of cases ,every second woman (50%) has complications during second trimester while pregnancy-induced hypertension and third trimester at pregnancy-induced hypertension has complications in 56,7% of cases ,and every third woman has fetoplacental insufficiency. The levels of В-2QP, S-100 and ANCA autoantibodies increase during pregnancy in women with gestational hypertension and pre-eclampsia. Quantification of the value of the level of autoantibodies directly depends on the severity of hypertensive disorders.

About the Author

N. A. Shakhbazova
Scientific-Research Institute of Obstetrics and Gynecology (Baku, Azerbaijan)


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For citations:

Shakhbazova N.A. CLINICAL AND IMMUNOLOGICAL COURSE OF GESTATION DURING PREGNANCY INDUCED HYPERTENSION. Obstetrics, Gynecology and Reproduction. 2014;8(3):11-17. (In Russ.)

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ISSN 2313-7347 (Print)
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