Stillbirth: prerequisites and risk factors
https://doi.org/10.17749/2313-7347/ob.gyn.rep.2020.137
Abstract
Here we analyze prerequisites and risk factors resulting in stillbirth. For this, we searched for key words in the electronic databases Scopus, MedLine, The Cochrane Library, CyberLeninka, RSCI etc. Social and medical history (obstetric and gynecological history, previous and identified extragenital diseases prior to pregnancy), bad habits, anthropometry data and pregnancy complications were assessed. Factors unambiguously linked to increased risk of stillbirth were identified.
About the Authors
V. F. Bezhenar
I.P. Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian Federation
Russian Federation
Vitaly F. Bezhenar - MD, Dr Sci Med, Professor, Head of the Department of Obstetrics, Gynecology and Neonatology, I.P. Pavlov First Saint Petersburg State Medical University.
6-8 Lev Tolstoy Str., Saint Petersburg 197022.
Russian Federation
Vitaly F. Bezhenar - MD, Dr Sci Med, Professor, Head of the Department of Obstetrics, Gynecology and Neonatology, I.P. Pavlov First Saint Petersburg State Medical University.
6-8 Lev Tolstoy Str., Saint Petersburg 197022.
L. A. Ivanova
S.M. Kirov Military Medical Academy, Ministry of Defense of Russian Federation
Russian Federation
Lidiya A. Ivanova - MD, PhD, Associate Professor, Department of Obstetrics and Gynecology, S.M. Kirov Military Medical Academy, Ministry of Defense of Russian Federation.
6 Akademika Lebedeva Str., Saint Petersburg 194044.
Russian Federation
Lidiya A. Ivanova - MD, PhD, Associate Professor, Department of Obstetrics and Gynecology, S.M. Kirov Military Medical Academy, Ministry of Defense of Russian Federation.
6 Akademika Lebedeva Str., Saint Petersburg 194044.
E. K. Ailamazyan
D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology
Russian Federation
Eduard К. Ailamazyan - MD, Dr Sci Med, Professor, Academician of RAS, Honored Scientist of Russian Federation, Scientific Director of the Department of Obstetrics and Perinatology, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology.
3 Mendeleevskaya liniya, Saint Petersburg 199034.
Russian Federation
Eduard К. Ailamazyan - MD, Dr Sci Med, Professor, Academician of RAS, Honored Scientist of Russian Federation, Scientific Director of the Department of Obstetrics and Perinatology, D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology.
3 Mendeleevskaya liniya, Saint Petersburg 199034.
References
1. Queenan J.T., Spong C.Y., Lockwood C.J. Protocols for high-risk pregnancies: an evidence-based approach. [Beremennost' vysokogo riska: protokoly, osnovannye na dokazatel'noj medicine. Per. s angl. pod red. A.D. Makatsariya, V.O. Bitsadze]. Moskva: GEOTAR-Media, 2018. 560 s. (In Russ.).
2. Suverneva A.A., Mamiev O.B. Some medical and social aspects of perinatal mortality in the Astrakhan region. [Nekotorye mediko-social'nye aspekty perinatal'noj smertnosti po Astrahanskoj oblasti]. Fundamental'nye issledovaniya. 2013;(5-1):148-51. (In Russ.).
3. Persianinov L.C., Kiryushchenkov A.P., Frolova O.G. Factors and high-risk groups of pregnant women. [Faktory i gruppy vysokogo riska beremennyh zhenshchin]. Akusherstvo i ginekologiya. 1976;(10):7-11. (In Russ.).
4. Bezhenar V.F., Ivanova L.A., Grigoryev S.G. High-risk pregnancy and perinatal losses. [Beremennost' «vysokogo riska» i perinatal'nye poteri]. Akusherstvo i ginekologiya. 2020;(3):42-7. (In Russ.). https://doi.org/10.18565/aig.2020.3.42-47.
5. Kamayev I.A., Khlapov A.L., Pyatilyshnova O.M. Perinatal death in Nizhny Novgorod region. [Perinatal'naya smertnost' v Nizhegorodskoj oblasti]. Obshchestvennoe zdorov'e i zdravoohranenie. 2007;(2):12-6. (In Russ.).
6. Bushmeleva N.N. Issues with regional medical aid, provided to women in mortality cases in the perinatal period. [Defekty okazaniya medicinskoj pomoshchi zhenshchinam v sluchayah smerti v perinatal'nom periode na urovne regiona]. Menedzher zdravoohraneniya. 2014;(11):27-36. (In Russ.).
7. Remneva O.V., Brusentsov I.G., Ershova E.G. Perinatal history and risk factors for childhood disability. [Perinatal'nyj anamnez i faktory riska detskoj invalidnosti]. Problemy klinicheskoj mediciny. 2011;(3-4):83-6. (In Russ.).
8. Strizhakov A.N., Ignatko I.V., Popova Yu.Yu. The etiology and pathogenesis of the antenatal death of the embryo. [Etiologiya i patogenez antenatal'noj gibeli ploda]. Voprosy ginekologii, akusherstva i perinatologii. 2012;11(3):31-40. (In Russ.).
9. Chabanova N.B., Khasanova V.V., Shevlyukova T.P. et al. Antenatal fetal death: causes, risk factors. [Antenatal'naya gibel' ploda: prichiny, faktory riska]. Universitetskaya medicina Urala. 2015;1(2-3):60-2. (In Russ.).
10. Rybalka A.N., Egorova Ya.A. Placental dysfunction and perinatal loss. [Placentarnaya disfunkciya i perinatal'nye poteri]. Krymskij zhurnal eksperimental'noj i klinicheskoj mediciny. 2012;2(3-4):50-4. (In Russ.).
11. Sergeyko I.V. Frequency of registrating certain risk factors of maternal and perinatal mortality. [Chastota registracii otdel'nyh faktorov riska materinskoj i perinatal'noj smertnosti]. Social'nye aspekty zdorov'ya naseleniya. 2015;(6):1-7. (In Russ.).
12. Nadzharyan I.G., Kostyuchek D.F. Risk factors of obstetric-gynecological pathology in pregnancy and delivery, resalting in perinatal losses. [Faktory riska akushersko-ginekologicheskoj patologii pri beremennosti i v rodah, privodyashchie k perinatal'nym poteryam]. Zhurnal akusherstva i zhenskih boleznej. 2004;53(1):49-54. (In Russ.).
13. Granatovich N.N., Frolova E.R. Regional features of mortinatality. [Regional'nye aspekty mertvorozhdaemosti]. Vestnik novyh medicinskih tekhnologij. 2018;25(3):223-6. (In Russ.).
14. Loginova E.I., Loginov I.A., Tayutina T.V., Egorov V.N. Screening of risk factors that determine outpatient antenatal mortality. [Skrining faktorov riska, opredelyayushchih antenatal'nuyu smertnost' na ambulatornom etape. Sbornik statej XII konferencii vrachej pervichnogo zvena zdravoohraneniya Yuga Rossii «Rannyaya diagnostika i sovremennye metody lecheniya na etape pervichnogo zvena zdravoohraneniya». Pod red. S.V. Shlyk, G.V. Shavkuty]. Rostov-na-Donu, 2017. 75-8. (In Russ.).
15. Vasilieva L.N., Kuzmich N.V., Kolysko D.V. Characterization of pregnancy and its outcomes in young primiparae. [Harakteristika beremennosti i ee iskhodov u yunyh pervorodyashchih]. Molodoj uchenyj. 2017;(44):45-8. (In Russ.).
16. Korneva Yu.S., Ukrainets R.V., Moiseenkova S.D. Features of perinatal losses in women older 35 years. [Osobennosti perinatal'nyh poter' u zhenshchin starshe 35 let]. Detskaya medicina Severo-Zapada. 2018;7(1):157-8. (In Russ.).
17. Mustafina G.G. Perinatal losses in adolescent women. X anniversary All-Russia Scientific and Educational Forum «Mother and Child». [Perinatal'nye poteri u zhenshchin podrostkov. X yubilejnyj Vserossijskij nauchno-obrazovatel'nyj forum «Mat' i ditya»]. Moskva, 2009. 491-2. (In Russ.).
18. Shaklycheva-Kompanets E.O. Juvenile pregnancy as one of the perinatal mortality and morbidity risk factors. [Yuvenil'naya beremennost' kak odin iz faktorov riska perinatal'noj smertnosti i zabolevaemosti]. Vestnik RUDN. Seriya: Medicina. 2011;(S5):311-9. (In Russ.).
19. Abdrakhmanov F.M., Kiryushchenkov A.P. Pesticides and reproductive health. [Pesticidy i reproduktivnoe zdorov'e]. Akusherstvo i ginekologiya. 1999;(4):13-5. (In Russ.).
20. Naumova E.V. Causal factors of antenatal fetal death. [Prichinnye faktory antenatal'noj gibeli ploda]. Byulleten' medicinskih internet-konferencij. 2017;7(6):796-7. (In Russ.).
21. Vetrov V.V., Ivanov D.O. Peer analysis of causes stillbirths in N-sky region for the year 2012. [Analiz prichin mertvorozhdenij v N-skoj oblasti v 2012 godu]. Byulleten' Federal'nogo Centra serdca, krovi i endokrinologii imeni V.A. Almazova. 2013;(2):12-8. (In Russ.)
22. Pestrikova T.Yu., Yurasova E.A., Butko T.M. Perinatal losses. Reduction reserves. [Perinatal'nye poteri. Rezervy snizheniya]. Moskva: Litterra, 2008. 200 s. (In Russ.).
23. Stepanova R.N., Kolomeets E.V. Maternal and perinatal outcomes of cervix diseases in pregnant women. [Materinskie i perinatal'nye iskhody pri zabolevaniyah shejki matki u beremennyh zhenshchin]. Uchenye zapiski Orlovskogo gosudarstvennogo universiteta. 2008;(2):218-23. (In Russ.).
24. Smith G.C., Pell J.P., Dobbie R. Caesarean section and risk of unexplained still birth in subsequent pregnancy. Lancet. 2003;362(9398):1779-84. https://doi.org/10.1016/s0140-6736(03)14896-9.
25. Orlova V.S., Kalashnikova I.V., Bulgakova E.V., Voronova Yu.V. Abdominal delivery as a medical and social problem of contemporary obstetrics. [Abdominal'noe rodorazreshenie kak mediko-social'naya problema sovremennogo akusherstva]. Zhurnal akusherstva i zhenskih boleznej. 2013;63(4):6-14. (In Russ.).
26. Mamedova S.N., Alieva L.M., Agaeva K.F. Comparative evaluation of the level of perinatal mortality and frequency of caesarean sections. [Sravnitel'naya ocenka urovnya perinatal'noj smertnosti i chastoty primeneniya operacii kesareva secheniya]. Obshchestvennoe zdorov'e i zdravoohranenie. 2016;(4):16-9. (In Russ.).
27. Pastarnak A.Yu. Current trends in the delivery of women with an operated uterus. [Sovremennye tendencii v rodorazreshenii zhenshchin s operirovannoj matkoj]. Sovremennye problemy nauki i obrazovaniya. 2014;(2). (In Russ.). Available at: https://science-education.ru/ru/article/view?id=12294. [Accessed: 10.04.2020].
28. Vetrov V.V., Ivanov D.O. The medical reasons of perinatal mortality in N-region of Southern Federal District of Russia in 2014 year. [Medicinskie prichiny perinatal'noj smertnosti v regione Yuzhnogo federal'nogo okruga Rossii v 2014 god]. Problemy zhenskogo zdorov'ya. 2015;10(1):20-7. (In Russ.).
29. Orlov V.M. Fertility in women after surgical correction of uterine malformations. [Detorodnaya funkciya u zhenshchin posle hirurgicheskoj korrekcii porokov razvitiya matki]. Voprosy ohrany materinstva i detstva. 1988;33(9):43-5. (In Russ.).
30. Malgina G.B., Repalova E.Yu. Perinatal aspects of pregnancy in women with abnormalities of the uterus. [Perinatal'nye aspekty beremennosti u zhenshchin s anomaliyami razvitiya matki]. Ural'skij medicinskij zhurnal. 2007;(2):8-10. (In Russ.).
31. Olina A.A., Sadykova G.K., Shirinkina E.V., Semyagina L.M. Comparative analysis of risk factors asmong women with antenatal fetal asphyxia. [Sravnitel'nyj analiz faktorov riska u zhenshchin s antenatal'noj asfiksiej ploda]. Medicinskaya nauka i obrazovanie Urala. 2018;19(2):14-8. (In Russ.).
32. Gardosi J., Madurasinghe V., Williams M. et al. Maternal and fetal risk factors for stillbirth: population based study. BMJ. 2013;346:f108. https://doi.org/10.1136/bmj.f108.
33. Maltseva L.I., Boronbaev A.K. Medical abortion and reproductive potential of women. [Medicinskij abort i reproduktivnyj potencial zhenshchin]. Medicinskij al'manah. 2010;(3):160-3. (In Russ.).
34. Kolesnikova O.M., Orazmuradov A.A., Kibardina N.V. et al. Perinatal outcomes at first labor after surgical and medical abortions. [Perinatal'nye iskhody u pervorodyashchih posle hirurgicheskogo i medikamentoznogo abortov]. Vestnik RUDN. Seriya: Medicina. 2012;(6):90-4. (In Russ.).
35. Strizhakov A.N., Ignatko I.V., Timokhina E.V., Belotserkovtseva L.D. Fetal growth retardation syndrome. Pathogenesis. Diagnostics. Treatment. Obstetric tactics. [Sindrom zaderzhki rosta ploda. Patogenez. Diagnostika. Lechenie. Akusherskaya taktika]. Moskva: GEOTAR-Media, 2012. 120 s. (In Russ.).
36. Cherednichenko T.S., Radzinsky V.E., Semyatov S.M. Gestation and delivery outcome in women with previous artificial abortion. [Beremennost' i rody u zhenshchin posle iskusstvennogo preryvaniya pervoj beremennosti i zdorov'e ih mladencev]. Vestnik RUDN. Seriya: Medicina. 2002;(1):108-12. (In Russ.).
37. Iversen O.E., Midboe G., Johnsen S.L. et al. Medical abortion - the first Norwegian experiences. Tidsskr Nor Laegeforen. 2003;123(17):2422-4.
38. Sheiner E., Sarid L., Levy A. et al. Obstetric risk factors and outcome of pregnancies complicated with early postpartum haemorrhage: a population-based study. J Matern Fetal Neonatal Med. 2005;18(3):149-54. https://doi.org/10.1080/14767050500170088.
39. Perederyaeva E.B., Pshenichnikova T.B., Donina E.V. et al. The course of pregnancy in women with metabolic syndrome in view of pathogenetic role of thrombophilia. [Techenie beremennosti u zhenshchin s metabolicheskim sindromom s uchetom patogeneticheskoj roli trombofilii]. Akusherstvo, Ginekologia i Reprodukcia. 2014;8(1):60-7. (In Russ.).
40. Bitsadze V.O., Makatsariya A.D., Khizroeva D.Kh. et al. Thrombophilia as a most important link in the pathogenesis of pregnancy complications. [Trombofiliya kak vazhnejshee zveno patogeneza oslozhnenij beremennosti]. Prakticheskaya medicina. 2012;5(60):22-30. (In Russ.).
41. Misnik V.V., Grom E.A., Klimova O.I. Molecular mechanisms of miscarriage. [Molekulyarnye mekhanizmy nevynashivaniya beremennosti]. Vestnik RUDN. Seriya: Medicina. 2003;(4):213-20. (In Russ.).
42. Makatsariya A.D., Shakhovskaya E.N. Prevention of recurrent pregnancy loss in patients with antiphospholipid syndrome. [Profilaktika povtornyh reproduktivnyh poter' pri antifosfolipidnom syndrome]. Vrach. 2008;(10):89-91. (In Russ.).
43. Gurieva V.M., Burumkulova F.F., Petrukhin V.A. et al. Obstetric and perinatal outcomes in pregnant women with type 2 diabetes patients. [Akusherskie i perinatal'nye iskhody u beremennyh s saharnym diabetom 2-go tipa]. Al'manah klinicheskoj mediciny. 2015;(37):18-23. (In Russ.).
44. Kirilchuk M.E. Perinatal loss in women with congenital heart disease. [Perinatal'nye poteri u zhenshchin s vrozhdennymi porokami serdca]. Perinatologiya i pediatriya. 2008;(1):43-51. (In Russ.).
45. Tetelyutina F.K. Optimization of obstetric care for patients with heart defects. [Optimizaciya akusherskoj pomoshchi bol'nym s porokami serdca]. Aktual'nye voprosy akusherstva i ginekologii. 2012;(2):20. (In Russ.).
46. Kazachkova E.A., Tukay K.S. The course features of pregnancy and labor as well as its outcomes in the women with the syndrome of dysplasia of heart connective tissue. [Osobennosti techeniya beremennosti i rodov, a takzhe ih iskhodov, u zhenshchin s sindromom displazii soedinitel'noj tkani serdca]. Ural'skij medicinskij zhurnal. 2009;(3):17-20. (In Russ.).
47. Eliasova L.G. Scientific substantiation of improving outpatient care for pregnant women with extragenital pathology in a large city. [Nauchnoe obosnovanie sovershenstvovaniya ambulatorno-poliklinicheskoj pomoshchi beremennym s ekstragenital'noj patologiej v usloviyah krupnogo goroda]. Avtoref. dis. kand. med. nauk. SPb., 2002. 16 s. (In Russ.).
48. Isokh S.L., Zhaksybaeva K.E. Pyelonephritis and pregnancy. Science and technology of Kazakhstan. [Pielonefrit i beremennost']. Nauka i tekhnika Kazahstana. 2007;(3):53-6. (In Russ.).
49. Nikolskaya I.G., Prokopenko E.I., Novikova S.V. et al. Complications and outcomes of pregnancy in chronic kidney disease. [Oslozhneniya i iskhody beremennosti pri hronicheskoj pochechnoj nedostatochnosti]. Al'manah klinicheskojmediciny. 2015;(37):52-69. (In Russ.).
50. Mangos G.J., Spaan J.J., Pirabhahar S., Brown M.A. Markers of cardiovascular disease risk after hypertension in pregnancy. JHypertens. 2012;30(2):351-8. https://doi.org/10.1097/HJH.0b013e32834e5ac7.
51. Menezes E.V., Yakoob M.Y., Soomro T. et al. Reducing stillbirths: prevention and management of medical disorders and infections during pregnancy. BMC Pregnancy Childbirth. 2009;9(Suppl 1):S4. https://doi.org/10.1186/1471-2393-9-S1-S4.
52. Kungurov N.V., Syrneva T.A., Berditskaya L.Yu. Syphilis morbidity in pregnant women and neonatal infants: epidemiological aspects. [Epidemiologicheskie aspekty zabolevaemosti sifilisom beremennyh i novorozhdennyh]. Rossijskij zhurnal kozhnyh i venericheskih boleznej. 2008;(1):56-8. (In Russ.).
53. Aksenenko V.A., Chebotarev V.V., Korobeinikova A.O. et al. Syphilis and pregnancy. Prevention of perinatal loss. [Sifilis i beremennost'. Profilaktika perinatal'nyh poter']. Medicinskij vestnik Severnogo Kavkaza. 2012;(1):57-60. (In Russ.).
54. Mingaleva N.V. The medical social characteristics of the gynecological morbidity. [Mediko-social'nye aspekty ginekologicheskoj zabolevaemosti]. Problemy social'noj gigieny, zdravoohraneniya i istorii mediciny. 2007;(4):21-4. (In Russ.).
55. Baranovskaya E.I., Znovets T.V., Zhavoronok S.V. Pregnancy in women with viral hepatitis C. [Beremennost' u zhenshchin s virusnym gepatitom S]. Rossijskij vestnik akushera-ginekologa. 2019;19(5):38— 42. (In Russ.). https://doi.org/10.17116/rosakush20191905138.
56. Magomedova Z.M. Perinatal aspects of viral hepatitis. [Perinatal'nye aspekty virusnogo gepatita]. Vestnik Volgogradskogo gosudarstvennogo medicinskogo universiteta. 2007;(S1):16-7. (In Russ.).
57. Alieva S.A., Khashaeva T.Kh. Rates of antiphospholipid antibodies circulation in patients with fetal loss syndrome and autoimmune diseases of thyroid. [Chastota cirkulyacii antifosfolipidnyh antitel u pacientok s sindromom poteri ploda i autoimmunnymi zabolevaniyami shchitovidnoj zhelezy]. Vestnik medicinskogo stomatologicheskogo instituta. 2012;(3):43-7. (In Russ.).
58. Ailamazyan E.K., Zainulina M.S. Hereditary thrombophilia: a differential approach to assessing the risk of obstetric complications. [Nasledstvennaya trombofiliya: differencirovannyj podhod k ocenke riska akusherskih oslozhnenij]. Akusherstvo i ginekologiya. 2010;(3):3— 9. (In Russ.).
59. Vorobiev A.V. Application of antiplatelet and angioprotective therapy in patients with placental insufficiency development risk factors. [Primenenie antiagregacionnoj i angioprotektivnoj terapii u pacientok s faktorami riska razvitiya placentarnoj nedostatochnosti]. Medicinskij sovet. 2016;(12):50-5. (In Russ.).
60. Makatsariya A.D., Bitsadze V.O., Khizroeva D.Kh., Hamani N.M. Placental insufficiency in complicated pregnancy and possibility of treatment with dipyridamole. [Placentarnaya nedostatochnost' pri oslozhnennoj beremennosti i vozmozhnost' primeneniya dipiridamola]. Akusherstvo, Ginekologia iReprodukcia. 2016;10(4):72-82. https://doi.org/10.17749/2313-7347.2016.10.4.072-082. (In Russ.).
61. Nikitina E.V., Gomon E.S., Ivanova M.A. Toxoplasmosis and pregnancy. [Toksoplazmoz i beremennost']. Ohrana materinstva i detstva. 2014;(2):75-9. (In Russ.).
62. Tantsurova K.S., Popova M.Yu., Kukhtik S.Yu., Fortygina Yu.A. Management tactics for pregnant women with myopia. [Taktika vedeniya beremennyh s miopiej]. Vestnik soveta molodyh uchenyh i specialistov Chelyabinskoj oblasti. 2016;(3):86-8. (In Russ.).
63. Markin L.B. Obesity as a risk factor for maternal and perinatal pathologies. [Ozhirenie kak faktor riska materinskoj i perinatal'noj patologii]. Reproduktivnaya endokrinologiya. 2011;(2):6-8. (In Russ.).
64. Goldenberg R.L., Kirby R., Culhane J.F. Stillbirth: a review. J Matern Fetal Neonatal Med. 2004;16(2):79—94. https://doi.org/10.1080/14767050400003801.
65. Chen A., Feresu S.A., Fernandez C., Rogand W.J. Maternal obesity and the risk of infant death in the United States. Epidemiology. 2009;20(1):74-81. https://doi.org/10.1097/EDE.0b013e3181878645.
66. Kolosova T.A., Gumenyuk E.G. The course of pregnancy and childbirth, perinatal outcomes in women with underweight. [Techenie beremennosti i rodov, perinatal'nye iskhody u zhenshchin s deficitom massy tela]. Vestnik RUDN. Seriya: Medicina. 2008;(7):318-23. (In Russ.).
67. Frolova E.R. The frequency of obesity in pregnant women. [Chastota ozhireniya sredi beremennyh]. Vestnik novyh medicinskih tekhnologij. 2018;(5). (In Russ.). Available at: http://medtsu.tula.ru/VNMT/Bulletin/E2018-5/1-7.pdf. [Accessed: 10.04.2020].
68. Kozhabekova T.A., Bekmolda M., Akhmetbekova A.S. Antenatal death of fetus: reasons and risk factors. [Antenatal'naya gibel' ploda prichiny i faktory riska]. Vestnik Kazahskogo Nacional'nogo medicinskogo universiteta. 2018;(3):4-8. (In Russ.).
69. Kovalenko B.L., Pasternak A.E., Pasternak I.A. Clinical and pathological analysis of perinatal mortality - methodological and methodical aspects, areas of improvement. [Kliniko-patologoanatomicheskij analiz perinatal'noj smertnosti - metodologicheskie i metodicheskie aspekty, napravleniya sovershenstvovaniya]. Medicinskaya nauka i obrazovanie Urala. 2013;14(4):86-90. (In Russ.).
70. Zhestkova N.V. Cholestatic hepatosis of pregnant women (pathogenesis, clinical features, treatment). [Holestaticheskij gepatoz beremennyh (patogenez, klinika, lechenie)]. Zhurnal akusherstva i zhenskih boleznej. 2010;59(1):91-7. (In Russ.).
71. Adamyan L.V., Filippov O.S., Artymuk N.V. et al. Acute fatty liver of pregnancy: intensive care and obstetric tactics. [Ostraya zhirovaya distrofiya pecheni u beremennyh: intensivnaya terapiya i akusherskaya taktika]. Anesteziologiya i reanimatologiya. 2018;63(1):79-86. (In Russ.). https://doi.org/10.18821/0201-7563-2018-63-1-79-86.
72. Burumkulova F.F., Petrukhin V.A., Tishenina R.S. et al. Obstetric and perinatal complications of gestational diabetes. [Akusherskie i perinatal'nye oslozhneniya pri gestacionnom saharnom diabete]. Zhurnal akusherstva i zhenskih boleznej. 2015;60(3):69-73. (In Russ.).
73. Mitkovskaya E.V., Kostin I.N., Smirnova T.V., Kuznetsova O.A. Regional features of obstetric and gynecological care in Russia. [Regional'nye osobennosti akushersko-ginekologicheskoj pomoshchi v Rossii]. Vestnik RUDN. Seriya: Medicina. 2016;(2):17-22. (In Russ.).
74. Cherezova J.M. Infringement of the biocenosis of the vagina at pregnant women. [Narushenie biocenoza vlagalishcha u beremennyh zhenshchin]. Fundamental'nye issledovaniya. 2012;(2-1):156-8. (In Russ.).
75. Kokina O.A., Guryeva V.A., Nemtseva T.V. The effect of syphilis therapy on the course and outcomes of pregnancy. [Vliyanie terapii sifilisa na techenie i iskhody beremennosti]. Medicinskoe obozrenie. Nauka i praktika. 2014;(2):15-20. (In Russ.).
76. Matyskina N.V., Taranushenko T.E. The effect of syphilitic infection on fetal growth and development. [Vliyanie sifiliticheskoj infekcii na rost i razvitie ploda]. Akusherstvo, Ginekologia i Reprodukcia. 2019;13(1):20-8. (In Russ.). https://doi.org/10.17749/2313-7347.2019.13.1.020-028.
77. Kokina O.A., Guryeva V.A., Evtushenko N.V., Nemtseva T.V. Features of the course and outcomes of pregnancy, depending on the volume and timeliness of syphilis therapy. [Osobennosti techeniya i iskhodov beremennosti v zavisimosti ot ob"ema i svoevremennosti terapii sifilisa]. Zhurnal akusherstva i zhenskih boleznej. 2011;60(4):48-54. (In Russ.).
78. Aksenenko V.A., Chebotarev V.V., Korobeinikova A.O. et al. Syphilis and pregnancy. Prevention of perinatal losses. [Sifilis i beremennost'. Profilaktika perinatal'nyh poter']. Medicinskij vestnik Severnogo Kavkaza. 2012;(1):57-60. (In Russ.).
79. Rymashevskiy A.N., Volkov A.E., Ursu L.P., Dunaeva G.G. Pregnancy, delivery and perinatal outcomes in women with syphilis. [Techenie beremennosti, rodov i perinatal'nyh iskhodov u bol'nyh zhenshchin sifilisom]. Sibirskoe medicinskoe obozrenie. 2007;(4):68-72. (In Russ.).
80. Perlamutrov Yu.N., Zatorskaya N.F. Diagnosis of early congenital syphilis. [Diagnostika rannego vrozhdyonnogo sifilisa]. Vestnik poslediplomnogo medicinskogo obrazovaniya. 2011;(2):37-9. (In Russ.).
81. Abramova S.V., Tyurina N.A., Chakhlova Yu.O., Aleshina K.E. Features of pregnancy, delivery and perinatal outcomes in patients with rhesussensitization. [Osobennosti techeniya beremennosti, rodov i perinatal'nye iskhody u pacientok s rezus-sensibilizaciej]. Colloquiumjournal. 2019;(6-1):40-2. (In Russ.).
82. Mamedalieva N.M., Sharipbaeva N.T., Daniyarov N.N., Dzhidzhilava G.M. Pregnancy, delivery and perinatal outcomes in patients with rhesus-sensitization. [Osobennosti techeniya beremennosti, rodov i perinatal'nye iskhody u pacientok s rezus-sensibilizaciej]. Vestnik Kazahskogo nacional'nogo medicinskogo universiteta. 2015;(1):18-21. (In Russ.).
83. Sokolov V.A., Abashin V.G., Admakin A.L. Burn injuries in pregnant women: prevalence, structure, outcomes. [Ozhogi u beremennyh: rasprostranennost', struktura, iskhody]. Voenno-medicinskij zhurnal. 2016;337(7):38-47. (In Russ.).
84. Shifman E.M., Pyregov A.V. Injury during pregnancy. [Travma vo vremya beremennosti]. Medicinskij alfavit. 2010;1-2(8):36-8. (In Russ.).
85. Abdrakhimova Ya.N., Suzdaltseva M.V. Cervical incompetence, current state of the problem. [Istmiko-cervikal'naya nedostatochnost', sovremennoe sostoyanie problemy. Aktual'nye problemy teoreticheskoj, eksperimental'noj, klinicheskoj mediciny i farmacii: materialy 52-j ezhegodnoj Vserossijskoj konferencii studentov i molodyh uchenyh, posvyashchennoj 90-letiyu doktora medicinskih nauk, professora, zasluzhennogo deyatelya nauki RF Pavla Vasil'evicha Dunaeva]. Tyumen', 2018. 24. (In Russ.).
86. Benoist G. Prediction of preterm delivery in symptomatic women (preterm labor). J Gynecol Obstet Biol Reprod Paris. 2016;45(10):1346-63. https://doi.org/10.1016/j.jgyn.2016.09.025.
87. Blanc J., Bretelle F. Predictive tools of preterm birth in asymptomatic high-risk pregnancy. J Gynecol Obstet Biol Reprod Paris. 2016;45(10):1261-79. https://doi.org/10.1016/j.jgyn.2016.09.009.
88. Berghella V., Rafael T.J., Szychowski J.M. et al. Cerclage for short cervix on ultrasonography in women with singleton gestations and previous preterm birth: a meta-analysis. Obstet Gynecol. 2011;117(3):663-71. https://doi.org/10.1097/aog.0b013e31820ca847.
89. Bespalova O.N., Sargsyan G.S. Selection of the method for correction of cervical incompetence. [Vybor metoda korrekcii istmiko-cervikal'noj nedostatochnosti]. Zhurnal akusherstva i zhenskih boleznej. 2017;66(3):157-68. (In Russ.). https://doi.org/10.17816/JOWD663157-168.
90. Astrakhantseva M.M., Breusenko L.E., Lebedev E.V. et al. Isthmicocervical insufficiency. Diagnosis and correction. [Istmiko-cervikal'naya nedostatochnost', diagnostika i korrekciya]. Rossijskij vestnik akushera-ginekologa. 2016;16(2):83-8. (In Russ.).
91. Novitskaya E.V. Modern approaches to the correction of cervical incompetence. [Sovremennye podhody k korrekcii istmiko-cervikal'noj nedostatochnosti]. Zhurnal akusherstva i zhenskih boleznej. 2016;65(S1):22. (In Russ.).
92. Dzhobava E.M., Sudakova G.Yu., Danelyan S.Zh. et al. Threatening premature birth and cervicoisthmic insufficiency: tactics and strategy of complex therapy. [Ugrozhayushchie prezhdevremennye rody i istmiko-cervikal'naya nedostatochnost': taktika i strategiya kompleksnoj terapii]. Voprosy ginekologii, akusherstva i perinatologii. 2012;11(4):41-6. (In Russ.).
93. Chernyaeva V.I., Neudakhina I.O., Zarechneva T.A. Pregnancy course and birth outcomes in women with cervical insufficiency. [Osobennosti techeniya beremennosti i iskhody rodov pri istmiko-cervikal'noj nedostatochnosti]. Fundamental'naya i klinicheskaya medicina. 2016;1(2):70-5. (In Russ.).
94. Marcellin L. Prevention of preterm birth by uterine cervical cerclage. J Gynecol Obstet Biol Reprod Paris. 2016;45(10):1299-323. https://doi.org/10.1016/j.jgyn.2016.09.022.
95. Pokusaeva V.N., Nikiforovsky N.K., Vakhrushina A.S. Prevention and management of excessive and inadequate gestational weight gain. [Profilaktika i korrekciya patologicheskogo uvelicheniya vesa pri beremennosti]. Uchenye zapiski Orlovskogo gosudarstvennogo universiteta. Seriya: Estestvennye, tekhnicheskie i medicinskie nauki. 2014;1(7):105-7. (In Russ.).
96. Weight gain during pregnancy: Reexamining the guidelines. Eds. K.M. Rasmussen, A.L. Yaktine. Washington, DC: The National Academies Press (US), 2009. 857 p. https://doi.org/10.17226/12584.
97. Asrankulova D.B., Akhmedova N.M., Bobokhodzhaeva N.V. Features of the anamnesis of pregnant women with reproductive losses. [Osobennosti anamneza beremennyh zhenshchin s reproduktivnymi poteryami]. Molodoj uchenyj. 2016;(5):203-5. (In Russ.).
98. Karashchuk E.V., Streltsova V.L. The question of the perinatal morbidity and mortality and ways of its reduction in a hospital obstetric and antenatal clinic. [K voprosu o perinatal'noj zabolevaemosti i smertnosti i putyah ih snizheniya v usloviyah akusherskogo stacionara i zhenskoj konsul'tacii]. Tihookeanskij medicinskij zhurnal. 2015;1(59):74-5. (In Russ.).
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For citations:
Bezhenar V.F., Ivanova L.A., Ailamazyan E.K. Stillbirth: prerequisites and risk factors. Obstetrics, Gynecology and Reproduction. 2020;14(5):634-643. (In Russ.) https://doi.org/10.17749/2313-7347/ob.gyn.rep.2020.137
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