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Pregnancy and childbirth in women with genetic or acquired thrombophilia is usually associated with a high risk to both thrombotic and obstetric complications and fruit. Unambiguous answer to the question of routine screening for thrombophilia in women with a history of obstetric history does not exist until now. It should be noted that the physiological hypercoagulable inherent pregnant, often for the first time reveals the background congenital and / or acquired disorders of hemostasis, which previously could be asymptomatic. A history of fetal loss syndrome, severe obstetric complications (severe preeclampsia, severe  twin-platsentranoy failure, fetal death, premature detachment of the placenta), thromboembolism is an indication for the study of genetic thrombophilia and antiphospholipid syndrome.

About the Author

D. L. Kapanadze
First Moscow State Medical Sechenov University of the Ministry of Health Russian Federation
Russian Federation


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For citations:

Kapanadze D.L. PREGNANCY AND CHILDBIRTH IN A YOUNG WOMAN WITH CONCOMITANT MUTATION IN LEIDEN AND PROTHROMBIN GENE G20210A. Obstetrics, Gynecology and Reproduction. 2014;8(2):34-38. (In Russ.)

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