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Septic shock

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The problem of sepsis and septic shock has recently become more and more actual. In obstetrics and gynaecology, the number of cases of sepsis has more than doubled over the past 10 years. The review examines the clinical forms of septic conditions, risk factors, pathogenesis of sepsis and septic shock, the main pathogens of septic conditions. Special attention is paid to neonatal sepsis. The relationship between septic shock and viral infections is considered in the context of the novel coronavirus infection caused by SARS-CoV-2 (COVID-19) pandemic. Hemostasis abnormalities have been demonstrated in patients with septic shock, including disseminated intravascular coagulation (DIC). The importance of determining the level of ADAMTS-13 to refine the forecast is discussed.

About the Authors

V. O. Bitsadze
Sechenov University
Russian Federation

Viktoria O. Bitsadze – MD, Dr Sci Med, Professor of RAS, Professor, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Scopus Author ID: 6506003478

Researcher ID: F-8409-2017

T. A. Sukontseva
I.P. Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian Federation
Russian Federation

Sukontseva Tatyana Alexandrovna - 6th year Student, Faculty of General Medicine

6/8 Lev Tolstoy Str., Saint Petersburg 197022

S. V. Akinshina
Sechenov University
Russian Federation

Svetlana V. Akinshina – MD, PhD, Researcher, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Ya. Yu. Sulina
Sechenov University
Russian Federation

Yana Yu. Sulina – MD, Assistant, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Scopus Author ID: 57194140583

Researcher ID: S-9569-2018


J. Kh. Khizroeva
Sechenov University
Russian Federation

Jamilya Kh. Khizroeva – MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Scopus Author ID: 57194547147

Researcher ID: F-8384-2017

M. V. Tretyakova
«Medical Center» LLC
Russian Federation

Maria V. Tretyakova – MD, PhD, Obstetrician-Gynecologist, Department of Gynecology

15/1 Timura Frunze Str., Moscow 119021

Kh. G. Sultangadzhieva
Sechenov University
Russian Federation

Khadizhat G. Sultangadzhieva – Postgraduate Student, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children's Health

62 Str. Zemlyanoi Val, Moscow 109004

J. Yu. Ungiadze
Shota Rustaveli Batumi State University; Iris Borchashvili Health Center Medina

Jumber Yu. Ungiadze – MD, Dr Sci Med, Professor, Faculty of Medicine, Batumi Shota Rustaveli State University; Director of the Iris Borchashvili Health Center Medina

35 Ninoshvili Str., Batumi, 6010, Georgia

237 Fridon Khalvashi Avenue, Batumi6004, Georgia

N. V. Samburova
Sechenov University
Russian Federation

Natalia V. Samburova – PhD, Associate Professor, Department of Pathophysiology, Institute of Clinical Medicine

62 Str. Zemlyanoi Val, Moscow 109004

K. N. Grigoreva
Sechenov University
Russian Federation

Kristina N. Grigoreva – 6th year Student, Faculty of Pediatrics

62 Str. Zemlyanoi Val, Moscow 109004

V. I. Tsibizova
Almazov National Medical Research Centre, Health Ministry of Russian Federation
Russian Federation

Valentina I. Tsibizova – MD, Department of Functional and Ultrasound Diagnostics

2 Akkuratova Str., Saint Petersburg 197341

A. S. Shkoda
City Clinical Hospital № 67 named after L.A. Vorokhobov, Moscow Healthcare Department
Russian Federation

Andrey S. Shkoda – MD, Dr Sci Med, Professor, Chief Physician

2/44 Salyama Adilya Str., Moscow 123423

D. V. Blinov
Institute for Preventive and Social Medicine; Lapino Clinic Hospital, MD Medical Group; Moscow Haass Medical - Social Institute
Russian Federation

Dmitry V. Blinov – MD, PhD, MBA, Head of Medical and Scientific Affairs; Neurologist; Faculty Member, Department of Neurology, Psychiatry and Narcology

4–10 Sadovaya-Triumfalnaya Str., Moscow 127006
1st Uspenskoye Highway, 111, Moscow Region, Odintsovo District, Lapino 143081
5, 1–1a 2nd Brestskaya Str., Moscow 123056


A. D. Makatsariya
Sechenov University
Russian Federation

Alexander D. Makatsariya – MD, Dr Sci Med, Professor, Academician of RAS, Head of the Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Scopus Author ID: 6602363216

Researcher ID: M-5660-2016


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For citations:

Bitsadze V.O., Sukontseva T.A., Akinshina S.V., Sulina Y.Yu., Khizroeva J.K., Tretyakova M.V., Sultangadzhieva K.G., Ungiadze J.Yu., Samburova N.V., Grigoreva K.N., Tsibizova V.I., Shkoda A.S., Blinov D.V., Makatsariya A.D. Septic shock. Obstetrics, Gynecology and Reproduction. 2020;14(3):314-326. (In Russ.)

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