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Combined hormonal contraceptives as a risk factor for cerebrovascular accident

https://doi.org/10.17749/2313-7347.2020.14.1.69-79

Abstract

Hormonal contraceptives are effective in preventing an unwanted pregnancy, but have side effects; among them stroke occupies an important place. The development of this serious disease may be associated with the hormonal drug components, but heavily dependent on additional risk factors for vascular and thrombotic complications such as smoking, arterial hypertension, genetically determined and acquired predisposition to thrombotic complications. This review presents an analysis of the most important risk factors for stroke such as genetic predisposition, hyperhomocysteinemia, thrombophilias in women using combined oral contraceptives.

About the Authors

M. G. Novosartyan
Kuban State Medical University, Health Ministry of Russian Federation
Russian Federation

Margarita G. Novosartyan - MD, Obstetrician-Gynecologist, Postgraduate Student, Department of Obstetrics, Gynecology and Perinatology.

4 Mitrofana Sedina St, Krasnodar 350063



N. V. Samburova
Sechenov University
Russian Federation

Natalia V. Samburova - MD, PhD, Associate Professor, Department of Pathophysiology, Institute of Clinical Medicine.

8 bild. 2, Trubetskaya St., Moscow 119991



E. V. Anichkova
Sechenov University
Russian Federation

Elizaveta V. Anichkova - 4th year student, Medical school Medicine of the Future.

8 bild. 2, Trubetskaya St., Moscow 119991



E. A. Bayanduryan
Kuban State Medical University, Health Ministry of Russian Federation
Russian Federation

Emmanuella A. Bayanduryan - MD, Obstetrician-Gynecologist, Postgraduate Student, Department of Obstetrics, Gynecology and Perinatology.

4 Mitrofana Sedina St, Krasnodar 350063



M. D. Andreeva
Kuban State Medical University, Health Ministry of Russian Federation
Russian Federation

Margarita D. Andreeva - MD, Dr Sci Med, Professor, Department of Obstetrics, Gynecology and Perinatology.

4 Mitrofana Sedina St, Krasnodar 350063



V. O. Bitsadze
Sechenov University
Russian Federation

Victoria O. Bitsadze - MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology, Institute of Children’s Health, Scopus Author ID: 6506003478, Researcher ID: F-8409-2017.

8 bild. 2, Trubetskaya St., Moscow 119991


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Review

For citations:


Novosartyan M.G., Samburova N.V., Anichkova E.V., Bayanduryan E.A., Andreeva M.D., Bitsadze V.O. Combined hormonal contraceptives as a risk factor for cerebrovascular accident. Obstetrics, Gynecology and Reproduction. 2020;14(1):69-79. (In Russ.) https://doi.org/10.17749/2313-7347.2020.14.1.69-79

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