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Indicators of the reproductive function after endoscopic surgical treatment of uterine myomas

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Aim: to characterize the function of the reproductive system in women after organ-preserving surgery for uterine myoma: hysteroresectoscopic (HRS) myomectomy and laparoscopic (LS) myomectomy.

Materials and methods. Forty one patients were examined and divided into 2 groups: Group 1 – 18 patients after HRS myomectomy and Group 2 – 23 patients after LS myomectomy. The control group included 20 healthy women of reproductive age.

Results. The HRS operation led to a significant decrease in the production of anti-Mullerian hormone (AMH), estradiol and progesterone, while the levels of luteinizing (LH) and follicle-stimulating (FSH) hormones increased. After myomectomy performed by the laparoscopic access, the levels of estradiol, progesterone, and AMH decreased but the levels of both LH and FSH increased so that the ratio LH/FSH remained unchanged. Almost all indices of gonadotropic and steroid hormone production became normalized over 6 months of the postoperative period.

Conclusion. The main factors of unfavorable prognosis in patients with ovarian tecoma are tumor necrosis, degree of malignancy and mitotic activity.

About the Authors

M. M. Vysotskiy
A.Y. Evdokimov State University of Medicine and Dentistry, Health Ministry of Russian Federation
Russian Federation

Maksim М. Vysotskiy – MD, PhD, Professor, Department of the Endoscopic Surgery (Head of the “Endoscopic Surgery in Gynecology” course)

20 bild. 1, Delegatskaya St., Moscow 127473, Russia.

I. I. Kuranov
S.P. Botkin City Clinical Hospital, Moscow Healthcare Department
Russian Federation

Ivan I. Kuranov – MD, Gynecologist, Department of Gynecology № 22

5 2nd Botkinsky passage, Moscow 125284, Russia.

O. B. Nevzorov
A.Y. Evdokimov State University of Medicine and Dentistry, Health Ministry of Russian Federation
Russian Federation

Oleg B. Nevzorov – PhD, Associate Professor, Department of Obstetrics and Gynecology

20 bild. 1, Delegatskaya St., Moscow 127473, Russia.


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For citation:

Vysotskiy M.M., Kuranov I.I., Nevzorov O.B. Indicators of the reproductive function after endoscopic surgical treatment of uterine myomas. Obstetrics, Gynecology and Reproduction. 2019;13(4):297-304. (In Russ.)

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)