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Neonatal meconium aspiration: risk factors and adaptation by the newborns

https://doi.org/10.17749/2313-7347.2018.12.4.005-014

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Abstract

Aim: to identify the risk factors of meconium aspiration and study its impact on neonatal adaptation. Materials and methods. Medical records of 44 women and their infants were studied. Results. In 85 % of cases, the diagnosis of complicated pregnancy was made, in 100 % cases – there was a complicated delivery; 100 % of newborns were put on mechanical ventilation, 95 % of them were diagnosed with cerebral depression syndrome, and 72.5 % – with aspiration pneumonia. Conclusion. A differentiated approach to the management of pregnancy and labor will reduce perinatal morbidity.

About the Authors

I. M. Bogomazova
I.M. Sechenov First Moscow State Medical University
Russian Federation

 PhD, Associate Professor, Department of Obstetrics, Gynecology and Perinatology, Faculty of General and Preventive Medicine

8/2 Trubetskaya St., Moscow 119991, Russia

+7(499)7823045



A. N. Strizhakov
I.M. Sechenov First Moscow State Medical University
Russian Federation

MD, PhD, Professor, Academician of RAS, Head of Department of Obstetrics and Gynecology, Faculty of General and Preventive Medicine

8/2 Trubetskaya St., Moscow 119991, Russia

+7(499)7823045



I. V. Ignatko
I.M. Sechenov First Moscow State Medical University
Russian Federation

MD, PhD, Professor, Corresponding Member of RAS, Department of Obstetrics, Gynecology and Perinatology, Faculty
of General and Preventive Medicine

8/2 Trubetskaya St., Moscow 119991, Russia

+7(499)7823045



V. S. Belousova
I.M. Sechenov First Moscow State Medical University
Russian Federation

PhD, Associate Professor, Department of Obstetrics, Gynecology and Perinatology, Faculty of General and Preventive Medicine

8/2 Trubetskaya St., Moscow 119991, Russia

+7(499)7823045



E. V. Timokhina
I.M. Sechenov First Moscow State Medical University
Russian Federation

MD, PhD, Professor, Department of Obstetrics and Gynecology, Faculty of General and Preventive Medicine

8/2 Trubetskaya St., Moscow 119991, Russia

+7(499)7823045



E. G. Pitskhelauri
I.M. Sechenov First Moscow State Medical University
Russian Federation

PhD, Associate Professor, Department of Obstetrics and Gynecology, Faculty of General and Preventive Medicine

8/2 Trubetskaya St., Moscow 119991, Russia

+7(499)7823045



M. A. Kardanova
I.M. Sechenov First Moscow State Medical University
Russian Federation

PhD, Assistant, Department of Obstetrics, Gynecology and Perinatology, Faculty of General and Preventive Medicine

8/2 Trubetskaya St., Moscow 119991, Russia

+7(499)7823045



N. V. Spiridonova
City Clinical Hospital named after S.S. Yudin
Russian Federation

Head of Neonatal Intensive Care Unit, Maternity Hospital

4 Kolomensky proezd, Moscow 115446, Russia



References

1. Public health in Russia 2017. Statistical book. [Zdravoohranenie v Rossii 2017. Statisticheskij sbornik]. Moskva: Rosstat, 2017. 170 s (in Russ.).

2. Haliti A., Mustafa L., Bexheti S. et al. In vitro action of meconium on bronochomotor tonus of newborns with meconium aspiration syndrome. Open Access Maced J Med Sci. 2018;6b(6):992–6.

3. Bondareva V.V., Gorelik K.D. Meconial aspiration, etiology, pathophysiological mechanisms, assistance at prehospital and hospital stages. [Mekonial'naya aspiraciya, etiologiya, patofiziologicheskie mekhanizmy, okazanie pomoshchi na dogospital'nom i gospital'nom etape]. Konferenciya, posvyashchennaya pamyati professora E.K. Cybul'kina: «E.K. Cybul'kin i razvitie neotlozhnoj pomoshchi detyam». Chast' 1. SPb., 2004. 28–32 (In Russ.). Available at: http://www.airspb.ru/c_tez_9.shtml. [Accessed: 14.10.2018].

4. Bushtyreva I.O., Chernavskiy V.V., Kolganova A.A. Syndrome of meconium aspiration. [Sindrom aspiracii mekoniya]. Saratovskij nauchno-medicinskij zhurnal. 2010;6(6):378–83 (in Russ.).

5. Mazurin A.V., Vorontsov I.M. Propaedeutics of childhood diseases. [Propedevtika detskih boleznej]. Moskva: Medicina, 1985. 441 s (in Russ.).

6. Saveleva G.M., Kurtser M.A., Klimenko P.A. et al. Intranatal protection of fetal health. [Intranatal'naya ohrana zdorov'ya ploda. Dostizheniya i perspektivy]. Akusherstvo i ginekologiya. 2005;(3):3–7 (in Russ.).

7. Sidorova I.S., Edokova A.B., Makarov I.O. et al. About the risk of aspiration syndrome developing in newborns. [O riske razvitiya aspiracionnogo sindroma u novorozhdennyh]. Rossijskij vestnik perinatologii i pediatrii. 2000;(3):13–6 (in Russ.).

8. Polnaszek B.E., Raghuraman N., Lopez J.D. et al. Neonatal morbidity in the offspring of obese women without hypertension or diabetes. Obstet Gynecol. 2018; Aug 17. DOI: 10.1097/AOG.0000000000002775. PMID: 30130347. [Epub ahead of print].

9. Shabalov N.P. Neonatology. Textbook: in 2 vol. Vol. 1: 3rd ed., cor. and add. [Uchebnoe posobie: v 2 t. T. 1: 3-e izd., ispr. i dop.]. Moskva: MEDpress-inform, 2004. 608 s (in Russ.).

10. Vinogradova I.V., Nikiforova G.I. Application of Surfactant BL in newborns with meconium aspiration syndrome. [Primenenie Surfaktanta BL u novorozhdennyh s sindromom aspiracii mekoniya]. Rossijskij vestnik perinatologii i pediatrii. 2011;(4):15–9 (in Russ.).

11. Methodical letter of Health Ministry and Social Development of Russian Federation from April 21, 2010 No. 15-4/10/2-3204 «Primary and resuscitative care for newborn children» for use in medical and preventive institutions providing medical care to newborns. [Metodicheskoe pis'mo Minzdravsocrazvitiya RF ot 21 aprelya 2010 g. № 15-4/10/2-3204 «Pervichnaya i reanimacionnaya pomoshch' novorozhdennym detyam» dlya ispol'zovaniya v rabote lechebnoprofilakticheskih uchrezhdenij, okazyvayushchih medicinskuyu pomoshch' novorozhdennym] (in Russ.). Available at: http://www.zaki.ru/pagesnew.php?id=71747. [Accessed: 14.10.2018].

12. Bandiya P., Nangia S., Saili A. Surfactant lung lavage vs. standard care in the treatment of meconium aspiration syndrome – a randomized trial. J Trop Pediatr. 2018; Jun 6. DOI: 10.1093/tropej/fmy024. PMID: 29878264. [Epub ahead of print].

13. Gandhi C.K. Management of meconium-stained newborns in the delivery room. Neonatal Netw. 2018;37(3):141–8.

14. Kabbur P.M., Herson V.C., Zaremba S. et al. Have the Year 2000 Neonatal Resuscitation Program guidelines changed the delivery room management or outcome of meconium-stained infants? J Perinatol. 2005;25:694–7.

15. Vain N.E, Szyld E.G., Prudent L.M. et al. Oropharyngeal and nasopharyngeal suctioning of the meconium-stained neonates before delivery of their shoulders: multicentre, randomized controlled trial. Lancet. 2004;364:597–602.

16. Xu H., Hofmeyr J., Roy C. et al. Intrapartum amnioinfusion for meconium-stained amniotic fluid: a systematic review of randomized controlled trials. BJOG. 2007;114:383–90.

17. Abramchenko V.V., Kiselev A.G., Orlova O.O. et al. Management of pregnancy and childbirth of high risk. [Vedenie beremennosti i rodov vysokogo riska]. Moskva: MIA, 2004. 400 s (in Russ.).

18. Fraser W.D., Hofmeyr J., Lede R. et al. Amnioinfusion for the prevention of the meconium aspiration syndrome. N Engl J Med. 2005;353:909–17.

19. Wiswell T.E., Gannon C.M., Jacob J. et al. Delivery room management of the apparently vigorous meconium-stained neonate: results of the multicenter, international collaborative trial. Pediatrics. 2000;105:1–7.

20. Yoder B.A., Kirsch Е.А., Barth W.H. et al. Changing obstetric practices associated with decreasing incidence of meconium aspiration syndrome. Obstet Gynecol. 2002;99:731–9.


For citation:


Bogomazova I.M., Strizhakov A.N., Ignatko I.V., Belousova V.S., Timokhina E.V., Pitskhelauri E.G., Kardanova M.A., Spiridonova N.V. Neonatal meconium aspiration: risk factors and adaptation by the newborns. Obstetrics, Gynecology and Reproduction. 2018;12(4):5-14. (In Russ.) https://doi.org/10.17749/2313-7347.2018.12.4.005-014

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ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)