Physiological indices of biological age in pregnant women of various age groups
https://doi.org/10.17749/2313-7347.2018.12.2.005-011
Abstract
The aims: to study the physiological indices, which characterize the biological age (BA) of the woman, in the process of physiological pregnancy and conduct a correlation analysis between these indices and the stage of pregnancy in different age groups. Materials and methods. Total of 122 pregnant women aged 20-34 years with different gestational age were selected for the study; all participants underwent a comprehensive functional examination. From the obtained results, the BA values were calculated using the in-depth «Kiev» scale as well as our own modification. Results. Upon an increase in the gestational age, there were changes in the BA-related indices in women of various age groups; these changes pertained to the vascular wall stiffness, respiratory functions, static balancing and the lens accommodation ability. Conclusion. The absence of changes in the BA, as calculated according to our modified test, during physiological pregnancy, suggests its applicability to women of young reproductive age. This calculation approach can be recommended for further studies in obstetrics and gynecology.
About the Authors
K. V. Zubavina
Ivanovo State Medical Academy, Health Ministry of Russian Federation
Russian Federation
Russian Federation
Zubavina Ksenia Valeryevna – Postgraduate Student, Department of Normal Physiology
8, Sheremetevskiy prospekt, Ivanovo, 153012
S. B. Nazarov
Ivanovo State Medical Academy, Health Ministry of Russian Federation;
Ivanovo Research Institute of Maternity and Childhood named after V.N. Gorodkov, Health Ministry of Russian Federation
Russian Federation
Russian Federation
Nazarov Sergey Borisovich – MD, Professor, Head of Department of Normal Physiology, ISMA HM of RF; Deputy Director for Science, IRIMC n.a. V.N. Gorodkov HM of RF
8, Sheremetevskiy prospekt, Ivanovo, 153012, 20, ul. Pobedy, Ivanovo, 153045
A. I. Malyshkina
Ivanovo State Medical Academy, Health Ministry of Russian Federation;
Ivanovo Research Institute of Maternity and Childhood named after V.N. Gorodkov, Health Ministry of Russian Federation
Russian Federation
Russian Federation
Malyshkina Anna Ivanovna – MD, Associate Professor, Head of Department of Obstetrics and Gynecology, Medical Genetics, ISMA HM of RF; Director of IRIMC n.a. V.N. Gorodkov HM of RF
8, Sheremetevskiy prospekt, Ivanovo, 153012, 20, ul. Pobedy, Ivanovo, 153045
A. A. Akimova
Ivanovo Research Institute of Maternity and Childhood named after V.N. Gorodkov, Health Ministry of Russian Federation
Russian Federation
Russian Federation
Akimova Anna Aleksandrovna – Postgraduate Student, Department of Obstetrics and Gynecology
20, ul. Pobedy, Ivanovo, 153045
A. B. Khuraseva
Kursk State Medical University, Health Ministry of Russian Federation
Russian Federation
Russian Federation
Khuraseva Anna Borisovna – MD, Professor, Department of Obstetrics and Gynecology, Faculty of Postgraduate Education
3, ul. Karla Marksa, Kursk, 305041
References
1. Voitenko V.P., Kozlovskaya S.G. Modern problems of gerontology and geriatrics. [Sovremennye problemy gerontologii i geriatrii]. Moskva: VNIIMI. 1988: 80 s (in Russian).
2. Kishkun A.A. Biological age and aging. [Biologicheskij vozrast i starenie]. Moskva: GEOTAR-Media. 2008: 973 s (in Russian).
3. Voitenko V.P. Biological age. In: Biology of Aging. [Biologicheskij vozrast. V kn.: Biologiya stareniya]. Leningrad: Nauka. 1982: 102-15 (in Russian).
4. Voitenko V.P. Biological age. In: Physiological mechanisms of aging. [Biologicheskij vozrast. V kn.: Fiziologicheskie mekhanizmy stareniya]. Moskva: Nauka. 1982: 144-56 (in Russian).
5. Coffi F., Gerasimov A.M., Posiseeva L.V., Dobrynina M.L. The state of biological age in women with infertility due to tubal peritoneal factor and external genital endometriosis. [Sostoyanie biologicheskogo vozrasta u zhenshchin s besplodiem, obuslovlennym trubno-peritoneal'nym faktorom i naruzhnym genital'nym endometriozom]. IV Regional'nyj nauchnyj forum «Mat' i ditya»: tezisy dokladov. Ekaterinburg. 2010: 155 (in Russian).
6. Belozerova L.M. Methodology for studying age-related changes. [Metodologiya izucheniya vozrastnyh izmenenij]. Klinicheskaya gerontologiya. 2002; 12: 3-7 (in Russian).
7. Zubavina K.V., Nazarov S.B. Modified method for determining biological age in women of young reproductive age. [Modificirovannaya metodika opredeleniya biologicheskogo vozrasta u zhenshchin molodogo reproduktivnogo vozrasta]. Mezhdunarodnaya nauchnaya konferenciya «Mediko-biologicheskie, klinicheskie i social'nye voprosy zdorov'ya i patologii cheloveka»: tezisy dokladov. Ivanovo. 2016: 142-3 (in Russian).
Review
For citations:
Zubavina K.V., Nazarov S.B., Malyshkina A.I., Akimova A.A., Khuraseva A.B. Physiological indices of biological age in pregnant women of various age groups. Obstetrics, Gynecology and Reproduction. 2018;12(2):5-11. (In Russ.) https://doi.org/10.17749/2313-7347.2018.12.2.005-011
Views:
729
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Email this article 
