Preview

Obstetrics, Gynecology and Reproduction

Advanced search

MATERNAL MORTALITY AND MATERNAL «NEAR MISS»: ARE THE CURRENT BLEEDING PREVENTION ALGORITHMS WORKING?

https://doi.org/10.17749/2313-7347.2018.12.1.062-072

Full Text:

Abstract

Bleeding during pregnancy, labor and delivery is considered the major cause of maternal death or subsequent disability, and various disorders. Currently, obstetricians and gynecologists have a number of effective tools for the prevention and treatment of obstetrical bleedings. Compliance with the Federal clinical protocols (recommendations) and the development of local algorithms for the treatment and prevention of obstetric hemorrhages are consistent with the organ-preserving treatment strategy and will help reduce maternal mortality and morbidity.

About the Authors

M. S. Zainulina
I.P. Pavlov First Saint Petersburg State Medical University, Health Ministry of Russian Federation; V.F. Snegirev Maternity Hospital № 6
Russian Federation

Zainulina Marina Sabirovna – MD, Professor, Department of Obstetrics, Gynecology and Reproduction, I.P. Pavlov FSPbSMU HM  of RF. Physician-in-Chief, V.F. Snegirev Maternity Hospital № 6.

6/8, ul. L'va Tolstogo, Saint Petersburg, 197022; 5, ul. Mayakovskоgo, Saint Petersburg, 192014



D. R. Eremeeva
V.F. Snegirev Maternity Hospital № 6
Russian Federation

Eremeeva Dina Rustemovna – PhD, Obstetrician-gynecologist, Head of the 2nd Obstetric Department of Obstetrics and Pregnancy Complications.

5, ul. Mayakovskоgo, Saint Petersburg, 192014



M. I. Krivonos
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Russian Federation

Krivonos Marina Ivanovna – Рostgraduate student.

3, Mendeleevskaya liniya, Saint Petersburg, 199034



References

1. Fifty-fifth Session of the United Nations General Assembly. New York: United Nations; 2000. Sep. 18. United Nations Millennium Declaration. General Assembly document, No. A/RES/55/2. URL: www.un.org/millennium/declaration/ares552e.pdf. [Accessed: 18.01.2018].

2. Souza J.P., Gulmezoglu A.M., Vogel J. et al. Moving beyond essen-tial interventions for reduction of maternal mortality (the WHO Multicountry Survey on Maternal and Newborn Health): a cross-sectional study. Lancet. 2013; 381(9879): 1747-55. DOI: 10.1016/S01406736(13)60686-8.

3. Say L., Pattinson R.C., Gülmezoglu A.M. WHO systematic review of maternal morbidity and mortality: the prevalence of severe acute maternal morbidity (near miss). Reprod Health. 2015; 1: 3. DOI: 10.1186/1742-4755-1-3. PMID: 15357863.

4. Ailamazyan E.K. Emergency care in extreme conditions in obstetric practice: guidance [Neotlozhnaya pomoshch' pri ekstremal'nyh sostoyaniyah v akusherskoj praktike: rukovodstvo]. SPb.: Izd-vo N-L. 2002: 432 s (in Russian).

5. Ailamazyan E.K., Repin M.A., Kuzminykh T.U. Obstetric bleeding: prevention and treatment [Akusherskie krovotecheniya: profilaktika i lechenie]. Akusherstvo i ginekologiya. 2009; 3: 15-20 (in Russian).

6. Ailamazyan E.K. Obstetrics: a textbook for medical universities [Akusherstvo: uchebnik dlya medicinskih vuzov]. SPb.: SpecLit. 1999: 544 s (in Russian).

7. Repin M.A., Kuzminy T.U., Zainulina M.S. et al. Obstetric bleeding: a manual for doctors [Akusherskie krovotecheniya: posobie dlya vrachej (Pod red. E.K. Ajlamazyana)]. SPb.: Izd-vo N-L. 2009: 60 s (in Russian).

8. Akulich T.I., Akulich N.S., Verbitsky V.S. et al. Obstetrics. Workshop: a tutorial in 2 parts. Part I [Akusherstvo. Praktikum: uchebnoe posobie v 2-h chastyah. Ch. I (Pod red. Yu.K. Malevicha)]. Minsk: BGMU. 2002: 121 s (in Russian).

9. Chattopadhyay S.K., Kharif H., Sherbeeni M.M. Placenta praevia and accreta after previous caesarean section. Eur J Obstet Gynecol Reprod Biol. 1993; 52 (3): 151-6.

10. Sukhikh G.T., Serov V.N., Savelieva G.M. et al. Prevention and therapy of massive blood loss in obstetrics [Profilaktika i terapiya massivnoj krovopoteri v akusherstve (Medicinskaya tekhnologiya)]. Moskva. 2010: 20 s (in Russian).

11. Vorobyov A.I., Gorodetsky V.M., Shulutko E.M., Vasiliev S.A. Acute massive hemorrhage [Ostraya massivnaya krovopoterya]. Moskva: GEOTAR-MED. 2001: 176 s (in Russian).

12. Serov V.I., Strizhakov A.I., Markin S.A. Guide to practical obstetrics [Rukovodstvo po prakticheskomu akusherstvu]. Moskva: MIA. 1997: 424 s (in Russian).

13. Savelyeva G.M., Kulakov V.I. Obstetrics: a textbook for medical universities [Akusherstvo: uchebnik dlya medicinskih vuzov]. Moskva: Medicina. 2000: 816 s (in Russian).

14. Zilber A.P. Blood loss and blood transfusion. Principles and methods of bloodless surgery [Krovopoterya i gemotransfuziya. Principy i metody beskrovnoj hirurgii]. Petrozavodsk: Izd-vo PetrGU. 1999: 120 s (in Russian).

15. Mazurok V.A., Lebedinsky K.M., Karelov A.E. Acute massive hemorrhage [Ostraya massivnaya krovopoterya]. SPb.: Izd-vo SPbMAPO. 2009: 192 s (in Russian).

16. Prophylaxis, treatment and algorithm of management for obstetric hemorrhages. Clinical recommendations (Protocol) [Profilaktika, lechenie i algoritm vedeniya pri akusherskih krovotecheniyah. Klinicheskie rekomendacii (Protokol)]. Moskva. 2014: 23 s (in Russian).

17. Girard T., Mörtl M., Schlembach D. New approaches to obstetric hemorrhage: the postpartum hemorrhage consensus algorithm. Curr Opin Anaesthesiol. 2014; 27 (3): 267-74.

18. Avdushkina L.A., Vavilova T.V., Zybina N.N. The method of thromboelastography/ thromboelastometry in assessing the hemostasis system: past and present. Reference intervals [Metod tromboelastografii/ tromboelastometrii v ocenke sistemy gemostaza: proshloe i nastoyashchee. Referentnye intervaly]. Kliniko-laboratornyj konsilium. 2009; 5: 26-33 (in Russian).

19. Grinevich T.N. Rotational thromboelastometry ROTEM as a new promising method for assessing the hemostasis system in patients with traumatological profile [Rotacionnaya tromboelastometriya ROTEM kak novyj perspektivnyj metod ocenki sistemy gemostaza u pacientov travmatologicheskogo profilya]. Novosti hirurgii. 2010; 18 (2): 115-22 (in Russian).

20. Gerasimovich G.I. Obstetrics: a manual for students [Akusherstvo: uchebnoe posobie dlya studentov]. Minsk: Belarus'. 2004: 815 s (in Russian).

21. Zainulina M.S. Premature detachment of the normally located placenta: pathogenetic aspects, predictable risk, prevention [Prezhdevremennaya otslojka normal'no raspolozhennoj placenty: patogeneticheskie aspekty, prognoziruemyj risk, profilaktika]. Avtoref. dis. dokt. med. nauk. SPb. 2006: 41 s (in Russian).

22. Barkagan Z.S., Momot A.P. Modern aspects of the pathogenesis, diagnosis and therapy of DIC syndrome [Sovremennye aspekty patogeneza, diagnostiki i terapii DVS-sindroma]. Vestnik gematologii. 2005; 1 (2): 5-14 (in Russian).

23. Makatsariya A.D., Mishenko A.L., Bitsadze V.O., Marov S.V. Syndrome of disseminated intravascular coagulation in obstetric practice [Sindrom disseminirovannogo vnutrisosudistogo svertyvaniya krovi v akusherskoj praktike]. Moskva: Triada-X. 2002: 496 s (in Russian).

24. Sidorova I.S., Kulakov V.I., Makarov I.O. Bleeding during pregnancy and childbirth: a study guide [Krovotecheniya vo vremya beremennosti i v rodah: uchebnoe posobie]. Moskva: MIA. 2006: 128 s (in Russian).

25. Fedorova Z.D., Levchenko L.B., Chuslov A.G. Hemodilution coagulopathy and features of infusion-transfusion therapy in obstetric practice [Gemodilyucionnaya koagulopatiya i osobennosti infuzionno-transfuzionnoj terapii v akusherskoj praktike]. Gematologiya i transfuziologiya. 1993; 8: 15-20 (in Russian).

26. Baryshev B.A., Eilamazyan E.K. Infusiontransfusion therapy of obstetric hemorrhages: a reference book for doctors [Infuzionnotransfuzionnaya terapiya akusherskih krovotechenij: spravochnik dlya vrachej]. SPb.: Izd-vo N-L. 2008: 55 s (in Russian).

27. Radzinsky V.E., Kostin I.N. Safe obstetrics [Bezopasnoe akusherstvo]. Akusherstvo i ginekologiya. 2007; 5: 12-6 (in Russian).

28. Papp Z., Toth-Pal E., Papp C. et al. Hypogastric artery ligation for intractable pelvic hemorrhage. Intern J Gynecol Obstet. 2006; 92: 27-31.

29. Chong Y.S., Su L.L., Arulkumaranb S. Current strategies for the prevention of postpartum haemorrhage in the third stage of labour Yap-Seng Chonga. Curr Opin Obstet Gynecol. 2004; 16 (2): 143-50.

30. Macphail S., Talks K. Massive post-partum haemorrhage and management of disseminated intravascular coagulation. Curr Obstet Gynaecol. 2004; 14 (2): 123-31.

31. Royston D., van Haaften N., De Vooght P. Aprotinin; friend or foe? A review of recent medical literature. Eur J Anesth. 2007; 24: 6-14.

32. Segal S., Shemesh I.Y., Blumenthal R. et al. Treatment of obstetric hemorrhage with recombinant activated factor VII (rRVIIa). Acta Haematol. 2002; 108: 162-3.

33. WHO guidelines for the management of postpartum haemorrhage and retained placenta. Geneva, Switzerland: WHO Press. 2009. URL: whqlibdoc.who.int/publications/2009/9789241598514_eng.pdf. [Accessed: 18.01.2018].

34. Kulakov V.I., Serov V.I., Abubakirova A.М. et al. Clinical transfusiology in obstetrics, gynecology and neonatology [Klinicheskaya transfuziologiya v akusherstve, ginekologii i neonatologii]. Moskva: Triada-X. 2001: 336 s (in Russian).

35. Rebarber A., Lonser R., Jackson S. et al. The safety of intraoperative autologous blood collection and autotransfusion during cesarean section. Am J Obstet Gynecol. 1998; 179 (3): 715-20.

36. Waters J.H., Tuohy M.J., Hobson D.F. et al. Bacterial reduction by cell salvage washing and leukocyte depletion filtration. Anesthesiology. 2003; 99 (3): 652-5.

37. Fong J., Gurewitsch E.D., Kang H.J. et al. An Analysis of Transfusion Practice and the Role of Intraoperative Red Blood Cell Salvage During Cesarean Delivery. Anesth Analg. 2007; 104 (3): 666-72.

38. Hanif M., Nourei S.M., Dunning J. Does the use of topical tranexamic acid in cardiac surgery reduce the incidence of post-operative mediastinal bleeding? Interact Cardiovasc Thorac Surg. 2004; 3 (4): 603-5.

39. Maddali M.M., Rajakumar M.C. Tranexamic Acid and primary coronary artery bypass surgery: a prospective study. Asian Cardiovasc Thorac Ann. 2007; 15 (4): 313-9.

40. El-Aroud K.A., Abushoffa A.M., Abdellatef H.E. Spectrophotometric and spectrofluorimetric methods for the determination of tranexamic acid in pharmaceutical formulation. Chem Pharm Bull (Tokyo). 2007; 55 (3): 364-7.

41. Benoni G., Fredin H., Knebel R. et al. Blood conservation with tranexamic acid in total hip arthroplasty: a randomized, double-blind study in 40 primary operations. Acta Orthop Scand. 2001; 72 (5): 442-8.

42. Tanaka N., Sakahashi H., Sato E. et al. Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee. J Bone Joint Surg Br. 2001; 83: 702-5.

43. Brown S., Thwaites B.K., Morgan P.D. Tranexamic acid is effective in decreasing postoperative bleeding and transfusions in primary coronary artery bypass operations: A double-blind, randomized, placebo-controlled trial. Anesth Analg. 1997; 85: 963-70.

44. Charbit B., Mandelbrot L., Samain E. et al. The decrease of fibrinogen is an early predictor of the severity of postpartum hemorrhage. J Thromb Haemost. 2007; 5 (2): 266-73.

45. Jin B., Du Y., Zhang F. et al. Carbetocin for the prevention of postpartum hemorrhage: a systematic review and meta-analysis of randomized controlled trials. J Matern Fetal Neonatal Med. 2015; 12: 1-8.

46. Bikmullina D.R. Molecular-genetic and biochemical indicators of the risk of coagulopathic bleeding in pregnant women with gestosis and its prophylaxis [Molekulyarno-geneticheskie i biohimicheskie pokazateli riska koagulopaticheskogo krovotecheniya u beremennyh s gestozom i ego profilaktika]. Avtoref. dis. kand. med. nauk. SPb. 2010: 23 s (in Russian).

47. Bokeria L.A., Samsonova N.N., Plyush M.G. et al. The use of recombinant activated VII clotting factor in clinical practice [Primenenie rekombinantnogo aktivirovannogo VII faktora svertyvaniya krovi v klinicheskoj praktike]. Annaly hirurgii. 2004; 1: 5-10 (in Russian).

48. Fedorova T.A., Strelnikova E.V., Rogachevsky O.V. Analysis of the multicenter application of recombinant coagulation factor VII (NovoSeven in the treatment of massive obstetric hemorrhages) [Analiz mnogocentrovogo primeneniya rekombinantnogo koagulyacionnogo faktora VII (NovoSehven v lechenii massivnyh akusherskih krovotechenij)]. Akusherstvo i ginekologiya. 2008; 4: 48-52 (in Russian).

49. Baudo F., Caimi T.M., Mostarda G. et al. Critical bleeding in pregnancy: a novel therapeutic approach to bleeding. Minerva Anestesiol. 2006; 72 (6): 389-93.

50. Boehlen F., Morales M.A., Fontane P. et al. Prolonged treatment of massive postpartum hemorrhage with recombinant factor VIIa: a case report and review of the literature. Br J Obstet Gynecol. 2004; 111: 284-7.

51. Bouwmeester F.W., Jonkhoff A.R., Vorheijen R., van Geijn H. Successful treatment of life Threatening postpartum hemorrhage with recombinant activated factor VII. Obstet Gynecol. 2003: 101: 1174-6.

52. Ogawa M., Akiahira S., Takahashi S. et al. Low-dose recombinant activated factor VII temporally stopped bleeding from small artery in severe postpartum hemorrhage: a case report. Blood Coagul Fibrinol. 2013; 24 (3): 344-6.

53. Momot A.P., Molchanova I.V., Tskhay V.B. Massive obstetric hemorrhages: from hysterectomy to pharmacotherapy [Massivnye akusherskie krovotecheniya: ot gisterektomii k farmakoterapii]. Voprosy ginekologii, akusherstva i perinatologii. 2012; 2: 32-7 (in Russian).

54. Sarode R., Milling T.J., Refaai M.A. et al. Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study. Circulation. 2013; 128 (11): 1234-43.

55. Song H.K., Tibayan F.A., Kahl E.A. et al. Safety and efficacy of prothrombin complex concentrates for the treatment of coagulopathy after cardiac surgery. J Thorac Cardiovasc Surg. 2014; 147 (3): 1036-40.

56. Geller S.E., Adams M.G., Kelly P.J. et al. Postpartum hemorrhage in resource-poor settings. Int J Gynaecol Obstet. 2006; 92 (3): 202-11.

57. Lebedeva N.V., Morozova Yu.V. Organ-saving technologies in the treatment of massive obstetric hemorrhages [Organosohranyayushchie tekhnologii v lechenii massivnyh akusherskih krovotechenij]. Medicinskij al'manah. 2016; 5 (45): 42-4 (in Russian).

58. В-Lynch C., Coker A., Lawal A. et al. The B-Lynch surgical technique for the control of massive postpartum haemorrhage: an alternative to hysterectomy? Five cases reported. Br J Obstet Gynaecol. 1997; 104 (3): 372-5.

59. Barkagan Z.S., Morozova L.I., Mamaev A.N. et al. Organosaving technology in the therapy of massive uterine bleeding [Organosberegayushchaya tekhnologiya v terapii massivnyh matochnyh krovotechenij]. Akusherstvo i ginekologiya. 2007; 1: 11-3 (in Russian).

60. Repina M.A., Levchenko L.B. Therapeutic tactics for obstetric hemorrhages [Lechebnaya taktika pri akusherskih krovotecheniyah]. Vestnik RAAG. 1995; 3: 65-7 (in Russian).


For citation:


Zainulina M.S., Eremeeva D.R., Krivonos M.I. MATERNAL MORTALITY AND MATERNAL «NEAR MISS»: ARE THE CURRENT BLEEDING PREVENTION ALGORITHMS WORKING? Obstetrics, Gynecology and Reproduction. 2018;12(1):62-72. (In Russ.) https://doi.org/10.17749/2313-7347.2018.12.1.062-072

Views: 92


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2313-7347 (Print)
ISSN 2500-3194 (Online)