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ANTITHROMBOTIC THERAPY IN CANCER PATIENTS
https://doi.org/10.17749/2313-7347.2015.10.1.026-037
Abstract
The article describes the main anticoagulant drugs used in cancer patients, taking into consideration pathogenetic aspects of hypercoagulation status in cancer patients: oral anticoagulants, heparin drugs, selective inhibitors of Xa factor. The basic advantages of low molecular weight heparin compared with unfractioned heparin. The comparison of low-molecular weight heparin drugs, their generics and biosimilar drugs is surveyed. Reviewed recommendations for the prevention of thrombotic complications in cancer patients. Overviewed the possible complications of heparin therapy and methods of prevention.
About the Authors
A. V. VorobevRussian Federation
MD, Ph.D., Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medical and Preventive Medicine First Moscow Medical Sechenov University. Address: ul. Zemlyanoy Val, 62, p. 1, Moscow, Russia, 109004. Tel.: +7(495)7885840
A. M. Chabrov
Russian Federation
MD, Ph.D., head of gynecological department Clinical Oncological Dispensary №1 Moscow Health Department. Address: ul. Volochaevskaya, 36, Moscow, Russia, 109033
A. A. Savchenko
Russian Federation
Ph.D., gynecological department Clinical Oncological Dispensary №1 Moscow Health Department. Address: ul. Volochaevskaya, 36, Moscow, Russia, 109033
A. D. Makatsariya
Russian Federation
MD, corresponding member of the Russian Academy of Sciences, Professor, Head of the Department of Obstetrics and Gynecology, Faculty of Medical and Preventive, First Moscow State Medical Sechenov University. Address: ul. Trubetskaya, 8, str. 2, Moskva, Russia, 119048. Tel.: +7(495)7885840
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Supplementary files
For citation: Vorobev A.V., Chabrov A.M., Savchenko A.A., Makatsariya A.D. ANTITHROMBOTIC THERAPY IN CANCER PATIENTS. Obstetrics, Gynecology and Reproduction. 2016;10(1):26-37. https://doi.org/10.17749/2313-7347.2015.10.1.026-037
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