THE SOCIO-MEDICAL CHARACTERISTICS OF WOMEN WITH THREATENED PRETERM LABOR

A. I. Malyshkina; A. O. Nazarova; A. A. Kozyrina; Yu. N. Zholobov; S. B. Nazarov

doi:10.17749/2313-7347.2016.10.2.037-043

THE SOCIO-MEDICAL CHARACTERISTICS OF WOMEN WITH THREATENED PRETERM LABOR

A. I. Malyshkina, A. O. Nazarova, A. A. Kozyrina, Yu. N. Zholobov, S. B. Nazarov

https://doi.org/10.17749/2313-7347.2016.10.2.037-043

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Abstract

Objective: to investigate health and social factors leading to the emergence of threatening preterm birth.

Material and methods: This study was designed to evaluate the significance of social conditions, professional and material factors, obstetric and somatic history in 191 singleton spontaneous gestations, included 117 women with threatened preterm labor (О47.0 in ICD) and 74 women with physiological pregnancy. Inclusion criteria for the main group were abdominal pain and structural changes in the cervix (maturation and shortening less than 2 cm). Medical records were also a source of information about the complications and the outcome of pregnancy. We calculated odds ratio and produced a ranking number of risk factors threatened preterm labor.

Results: average general education, signs of a threatened abortion in the second trimester, smoking during pregnancy, asymptomatic bacteriuria and the presence of immunoglobulin G (IgG) antibody to Cytomegalovirus (CMV) are the most significant risk factors for threatened preterm labor.

Conclusion. It is necessary to conduct preconception preparation of women with above mentioned poor factors, as well as measures aimed at elimination of controllable risk factors, to reduce the likelihood of threatened preterm birth.

Keywords

pregnancy, threatened preterm labor, risk factors, CMV

About the Authors

A. I. Malyshkina

Federal State Budgetary Institution "Ivanovo Research Institute of Maternity and Childhood named after V.N. Gorodkov" Ministry of Health of the Russian Federation; State Budgetary Educational Institution of higher education "Ivanovo State Medical Academy" Ministry of Health of the Russian Federation
Russian Federation

MD, Associate professor, Director, ul. Pobedy, 20, Ivanovo, 153045;

Head of the department of obstetrics and gynecology, medical genetics, Sheremet'evskii proezd, 8, Ivanovo, 153000

A. O. Nazarova

State Budgetary Educational Institution of higher education "Ivanovo State Medical Academy" Ministry of Health of the Russian Federation
Russian Federation

PhD, Associate professor of the department of obstetrics and gynecology, medical genetics,

Sheremet'evskii proezd, 8, Ivanovo, 153000

A. A. Kozyrina

Federal State Budgetary Institution "Ivanovo Research Institute of Maternity and Childhood named after V.N. Gorodkov" Ministry of Health of the Russian Federation
Russian Federation

Doctoral student,

ul. Pobedy, 20, Ivanovo, 153045

Yu. N. Zholobov

Federal State Budgetary Institution "Ivanovo Research Institute of Maternity and Childhood named after V.N. Gorodkov" Ministry of Health of the Russian Federation
Russian Federation

Doctoral student,

ul. Pobedy, 20, Ivanovo, 153045

S. B. Nazarov

Federal State Budgetary Institution "Ivanovo Research Institute of Maternity and Childhood named after V.N. Gorodkov" Ministry of Health of the Russian Federation
Russian Federation

MD, Professor, assistant Director on science,

ul. Pobedy, 20, Ivanovo, 153045

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For citation:

Malyshkina A.I., Nazarova A.O., Kozyrina A.A., Zholobov Y.N., Nazarov S.B. THE SOCIO-MEDICAL CHARACTERISTICS OF WOMEN WITH THREATENED PRETERM LABOR. Obstetrics, Gynecology and Reproduction. 2016;10(2):37-43. (In Russ.) https://doi.org/10.17749/2313-7347.2016.10.2.037-043