akusherstvoObstetrics, Gynecology and ReproductionАкушерство, Гинекология и Репродукция2313-73472500-3194IRBIS LLCakusherstvo-99Research ArticleREVIEW ARTICLEНАУЧНЫЙ ОБЗОРCLINICAL PICTURE, DIAGNOSIS AND PREVENTION OF VENOUS THROMBOEMBOLIC COMPLICATIONS DURING PREGNANCYКЛИНИКА, ДИАГНОСТИКА И ПРОФИЛАКТИКА ВЕНОЗНЫХ ТРОМБОЭМБОЛИЧЕСКИХ ОСЛОЖНЕНИЙ ВО ВРЕМЯ БЕРЕМЕННОСТИАкиньшинаС. В.AkinshinaS. V.МакацарияА. Д.MakatsariyaA. D.БицадзеВ. О.BitsadzV. O.gemostasis@mail.ruАндрееваМ. Д.AndreevaM. D.ГБОУ ВПО «Первый МГМУ имени И.М. Сеченова» Минздрава России, МоскваРоссияFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationRussian FederationГБОУ ВПО «Первый МГМУ имени И.М. Сеченова» Минздрава России, МоскваРоссияFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationRussian Federation201414062016842736Copyright © Akinshina S.V., Makatsariya A.D., Bitsadz V.O., Andreeva M.D., 20162016Акиньшина С.В., Макацария А.Д., Бицадзе В.О., Андреева М.Д.Akinshina S.V., Makatsariya A.D., Bitsadz V.O., Andreeva M.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gynecology.su/jour/article/view/99

Despite intensive research, venous thromboembolism still accounts for significant maternal mortality and morbidity. The article describes modern aspects of the pathogenesis, diagnosis, treatment, primary and secondary prevention of venous thromboembolism during pregnancy. Thrombophilia might be the essential pathogenetic mechanism of thromboembolism associated with pregnancy. Low molecular weight heparin (LMWH) is effective for prevention of recurrent thromboembolism and obstetric complications. Women with personal or family history of thromboembolism or with history of obstetric complications should be screened for thrombophilia.

Несмотря на интенсивные исследования в этой области, венозные тромбоэмболические осложнения по-прежнему являются одной из ведущих причин материнской смертности. В статье описаны современные аспекты патогенеза, диагностики, лечения, первичной и вторичной профилактики венозной тромбоэмболии во время беременности. Тромбофилия является одним из важнейших патогенетических механизмов развития тромбоэмболий, связанных с беременностью. Низкомолекулярный гепарин является эффективным для профилактики рецидивирующих тромбозов и акушерских осложнений. Женщины с отягощенным личным и семейным анамнезом по тромбозам или тяжелыми акушерскими осложнениями в анамнезе должны быть обследованы на предмет тромбофилии.

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The authors declare that there are no conflicts of interest present.