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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-90</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ОRIGINAL ARTICLES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group></article-categories><title-group><article-title>PLASMAPHERESIS IN COMPLEX TREATMENT OF PREGNANT WOMEN WITH ACUTE APPENDICITIS</article-title><trans-title-group xml:lang="ru"><trans-title>ПЛАЗМАФЕРЕЗ В КОМПЛЕКСНОМ ЛЕЧЕНИИ БЕРЕМЕННЫХ С ОСТРЫМ АППЕНДИЦИТОМ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хворостухина</surname><given-names>Н. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Khvorostukhina</surname><given-names>N. F.</given-names></name></name-alternatives><email xlink:type="simple">Khvorostukhina-NF@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Салов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Salov</surname><given-names>I. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новичков</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Novichkov</surname><given-names>D. A.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО Саратовский ГМУ им. В.И. Разумовского Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saratov State Medical University named after V.I. Razumovsky Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>14</day><month>06</month><year>2016</year></pub-date><volume>8</volume><issue>3</issue><fpage>26</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Khvorostukhina N.F., Salov I.A., Novichkov D.A., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Хворостухина Н.Ф., Салов И.А., Новичков Д.А.</copyright-holder><copyright-holder xml:lang="en">Khvorostukhina N.F., Salov I.A., Novichkov D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/90">https://www.gynecology.su/jour/article/view/90</self-uri><abstract><p>The results of dynamic studies of the stress hormoneof prolactin and indicators of endogenous intoxication in pregnant women having undergone surgery for acute appendicitis are presented. The scientific justification for additional use of discrete plasmapheresis on 3rd and 5th days after an operation in the complex of therapeutic measures that contribute to the preservation of stable concentration of prolactin and allows 2 times to reduce the frequency of pregnancy loss is given.</p></abstract><trans-abstract xml:lang="ru"><p>Представлены результаты динамического исследования стрессорного гормона пролактина и показателей эндогенной интоксикации у беременных, перенесших оперативное вмешательство по поводу острого аппендицита. Дается научное обоснование необходимости дополнительного использования в комплексе лечебных мероприятий дискретного плазмафереза на 3-е и 5-е сутки после операции, что способствует сохранению стабильных концентраций пролактина и позволяет в 2 раза уменьшить частоту потерь беременности.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>АППЕНДИЦИТ</kwd><kwd>БЕРЕМЕННОСТЬ</kwd><kwd>ПРОЛАКТИН</kwd><kwd>ПОКАЗАТЕЛИ ЭНДОГЕННОЙ ИНТОКСИКАЦИИ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>appendicitis</kwd><kwd>pregnancy</kwd><kwd>prolactin</kwd><kwd>indicators of endogenous intoxication</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Акушерство: национальное руководство. Под ред. Э.К. Айламазяна, В.И. Кулакова, В.Е. Радзинского, Г.М. Сидельниковой. М. 2007; 1200 с.</mixed-citation><mixed-citation xml:lang="en">Obstetrics: national leadership. Ed. 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