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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347/ob.gyn.rep.2020.190</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-880</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group></article-categories><title-group><article-title>Serous papillary cystadenofibroma combined with extended external genital endometriosis</article-title><trans-title-group xml:lang="ru"><trans-title>Сочетание серозной папиллярной цистаденофибромы яичника с распространенным наружным генитальным эндометриозом</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4043-907X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сыркашев</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Syrkashev</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сыркашев Егор Михайлович – научный сотрудник отделения лучевой диагностики</p><p>Scopus Author ID: 57204631271</p><p>117997, Москва, ул. академика Опарина, д. 4</p></bio><bio xml:lang="en"><p>Egor M. Syrkashev – Researcher, Department of Radiology</p><p>Scopus Author ID: 57204631271</p><p>4 Academika Oparina Str., Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4768-115X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Солопова</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Solopova</surname><given-names>A. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Солопова Алина Евгеньевна – д.м.н., доцент, ведущий научный сотрудник отделения лучевой диагностики</p><p>Scopus Author ID: 24460923200. Researcher ID: P-8659-2015</p><p>117997, Москва, ул. академика Опарина, д. 4</p></bio><bio xml:lang="en"><p>Alina E. Solopova – MD, Dr Sci Med, Associate Professor, Leading Researcher, Department of Radiology</p><p>Scopus Author ID: 24460923200. Researcher ID: P-8659-2015</p><p>4 Academika Oparina Str., Moscow 117997</p></bio><email xlink:type="simple">dr.solopova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8739-5209</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Асатурова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Asaturova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Асатурова Александра Вячеславовна – к.м.н., старший научный сотрудник патологоанатомического отделения</p><p>Scopus Author ID: 57190118907</p><p>117997, Москва, ул. академика Опарина, д. 4</p></bio><bio xml:lang="en"><p>Alexandra V. Asaturova – MD, PhD, Senior Researcher, Department of Pathology</p><p>Scopus Author ID: 57190118907</p><p>4 Academika Oparina Str., Moscow 117997</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kulakov National Medical Research Center for Obstetrics, Gynecology and Perinatology, Health Ministry of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>09</day><month>01</month><year>2021</year></pub-date><volume>14</volume><issue>6</issue><fpage>694</fpage><lpage>703</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Syrkashev E.M., Solopova A.E., Asaturova A.V., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Сыркашев Е.М., Солопова А.Е., Асатурова А.В.</copyright-holder><copyright-holder xml:lang="en">Syrkashev E.M., Solopova A.E., Asaturova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/880">https://www.gynecology.su/jour/article/view/880</self-uri><abstract><p>Ovarian cystadenofibroma (CAF) is a rare ovarian tumor originating both from epithelial and stromal components being, however, classified as epithelial tumors. CAF prevalence among all ovarian tumors does not exceed more than 1.7 %. CAFs are commonly asymptomatic, in extremely rare cases of large tumor or ovarian torsion pain sensation may be noted. External genital endometriosis (EGE) is a chronic gynecological disorder that occurs in women of reproductive age and cause infertility and pelvic pain. EGE prevalence comprises around 10 % in women of reproductive age, 20–50 % in women with infertility, and almost 90 % in women with chronic pelvic pain. Magnetic resonance imaging (MRI) is method of choice in diagnostics of such pathology due to the high natural soft tissue contrast and functional techniques such as diffusion-weighted images (DWI) and dynamic contrast enhancement (DCE). Surgery planning, necessity for systemic therapy or follow-up directly depend on imaging and diagnostic laparoscopy results. Here we present a clinical case of rarely combined serous papillary CAF with extended EGE accompanied with consequences of intra-tumoral hemorrhage. Case study demonstrates main visualization characteristics that provide correct differential diagnosis and exclude malignancy transformation.</p></abstract><trans-abstract xml:lang="ru"><p>Цистаденофибромы яичников (ЦАФ) представляют собой редкие опухоли яичников, которые развиваются как из эпителиальных, так и из стромальных компонентов, но классифицируются как эпителиальные опухоли. Доля ЦАФ среди всех опухолей яичников составляет не более 1,7 %. Как правило, ЦАФ бессимптомны, в крайне редких случаях (при больших размерах опухоли/формировании перекрута яичника) могут возникать болевые ощущения. Наружный генитальный эндометриоз (НГЭ) – хроническое гинекологическое заболевание, которое встречается у женщин репродуктивного возраста и может вызывать бесплодие и тазовые боли. Распространенность составляет приблизительно 10 % среди женщин репродуктивного возраста, 20–50 % у женщин с бесплодием и почти 90 % среди женщин с хронической тазовой болью. Магнитно-резонансная томография (МРТ) является методом выбора в диагностике данного вида патологий ввиду высокого естественного контраста мягких тканей и функциональных методик, таких как диффузионно-взвешенные изображения (ДВИ) и динамическое контрастное усиление (ДКУ). Планирование объема оперативного вмешательства, необходимость проведения системной терапии или динамическое наблюдение напрямую зависят от результатов визуальной диагностики и данных диагностической лапароскопии. В работе представлено клиническое наблюдение редкого сочетания – распространенного НГЭ и серозной ЦАФ с последствиями кровоизлияния в структуру; приведены основные визуализационные характеристики, позволившие провести корректный дифференциальный диагноз, исключить малигнизацию процесса.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоль яичника</kwd><kwd>цистаденофиброма</kwd><kwd>магнитно-резонансная томография</kwd><kwd>МРТ</kwd><kwd>эндометриоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ovarian tumor</kwd><kwd>cystadenofibroma</kwd><kwd>magnetic resonance imaging</kwd><kwd>MRI</kwd><kwd>endometriosis</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках реализации Гранта Президента РФ для государственной поддержки молодых российских ученых – докторов наук «Разработка алгоритмов диагностики и мониторинга лечения опухолей яичников на основе комплексного применения лучевых и лабораторных методов исследования» (МД-130.2019.7).</funding-statement><funding-statement xml:lang="en">This work was supported by the Grant of the President of the Russian Federation "Development of algorithms for diagnostics and monitoring treatment of ovarian tumors by combing based on the complex application of radiological imaging and laboratory-based methods" (MD-130.2019.7).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cho S.-M., Byun J.Y., Rha S.E. et al. 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