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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347/ob.gyn.rep.2020.150</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-875</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕ</subject></subj-group></article-categories><title-group><article-title>Features of labor course upon with preterm rupture of membranes and "mature" cervix at gestation of 37 weeks or higher</article-title><trans-title-group xml:lang="ru"><trans-title>Особенности течения родов при преждевременном разрыве плодных оболочек и «зрелой» шейке матке в сроке 37 недель и выше</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5879-418X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каганова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaganova</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каганова Мария Александровна – к.м.н., доцент кафедры акушерства и гинекологии ИПО</p><p>443099 Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Maria A. Kaganova – MD, PhD, Associate Professor, Department of Obstetrics and Gynecology</p><p>89 Chapaevskaya Str., Samara 443099</p></bio><email xlink:type="simple">mkaganova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3928-3784</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Спиридонова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Spiridonova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Спиридонова Наталья Владимировна – д.м.н., профессор, зав. кафедрой акушерства и гинекологии ИПО</p><p>443099 Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Natalia V. Spiridonova – MD, Dr Sci Med, Professor, Head of the Department of Obstetrics and Gynecology</p><p>89 Chapaevskaya Str., Samara 443099</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3929-4187</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Безрукова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bezrukova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Безрукова Алина Андреевна – врач акушер-гинеколог</p><p>443069 Самара, ул. Революционная, д. 144</p></bio><bio xml:lang="en"><p>Alina A. Bezrukova – MD, Obstetrician-Gynecologist</p><p>144 Revolutsionnaya Str., Samara 443069</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4036-463X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медникова</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Mednikova</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Медникова Ольга Михайловна – врач акушер-гинеколог</p><p>443087 Самара, пр. Кирова, д. 228</p></bio><bio xml:lang="en"><p>Olga M. Mednikova – MD, Obstetrician-Gynecologist</p><p>228 Kirov Ave., Samara 443087</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7006-5828</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведчикова-Ардия</surname><given-names>Л. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedchikova-Ardia</surname><given-names>L. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Медведчикова-Ардия Лали Корнелевна – врач акушер-гинеколог</p><p>443095 Самара, Ташкентская ул., д. 159</p></bio><bio xml:lang="en"><p>Lali K. Medvedchikova-Ardia – MD, Obstetrician-Gynisecologt</p><p>159 Tashkentskaya Str., Samara 443095</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University, Health Ministry of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ Самарской области «Самарская городская поликлиника № 13 Железнодорожного района»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara City Polyclinic № 13 of the Railway Region</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ Самарской области «Самарская городская поликлиника № 6 Промышленного района»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara City Polyclinic № 6 of the Industrial District</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУЗ Самарской области «Самарская областная клиническая больница имени В.Д. Середавина»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Seredavin Samara Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>09</day><month>01</month><year>2021</year></pub-date><volume>14</volume><issue>6</issue><fpage>646</fpage><lpage>658</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kaganova M.A., Spiridonova N.V., Bezrukova A.A., Mednikova O.M., Medvedchikova-Ardia L.K., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Каганова М.А., Спиридонова Н.В., Безрукова А.А., Медникова О.М., Медведчикова-Ардия Л.К.</copyright-holder><copyright-holder xml:lang="en">Kaganova M.A., Spiridonova N.V., Bezrukova A.A., Mednikova O.M., Medvedchikova-Ardia L.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/875">https://www.gynecology.su/jour/article/view/875</self-uri><abstract><p>Introduction. Management and the prevalence of labor complications in patients with premature rupture of the membranes (PROM) is a pressing issue. Aim: to assess the features of childbirth course in patients with PROM during a full-term pregnancy and a favourable cervix. Materials and methods. А prospective analysis of labor course and the postpartum period was performed in 189 patients with a singleton pregnancy with occipital presentation, at least 37-week gestation, of low and moderate risk groups, without contraindications for vaginal delivery. PROM as complicated pregnancy was found in 89 subjects (main group), whereas 100 having labor onset with intact fetal membranes were enrolled into comparison group. The features of labor course were analyzed. Results. Primiparous patients dominated in the main group (66.7 %). The latent period between amniotic fluid discharge to labor onset comprised 4.15 ± 3.48 hours and 3.40 ± 2.13 hours in primiparous and multiparous women, respectively, whereas labor activity in 19 % of women did not develop after 6 hour-latent period. The average duration of labor did not depend on the patient parity and was longer in the group with PROM: 8.06 ± 3.51 hours – in primiparous females, 7.21 ± 2.56 hours – in comparison group (T = –1.99; p = 0.04) due to prolonged first stage of labor. In patients with and without PROM, rate of poor uterine contraction strength was 24.7 % and 18.3 % (p = 0.29), cervical dystocia – 2.25 % and 0 % (p = 0.13), use of oxytocin in childbirth – 35.9 % and 18.3 % (p = 0.007), respectively. Caesarean sections in the main group were recorded in 15 cases (16.85 %), fetal vacuum extraction – 6 cases (6.74 %), whereas in the comparison group – per 2 (2,0 %) cases, respectively (χ2 = 16.13; p &lt; 0.001). Conclusion. Patients with PROM and favourable cervix were shown to have duration of labor, occurrence of operative delivery, rupture of the cervix, and use of oxytocin lasting substantially longer compared to those with the rupture of membranes after onset of the labor. PROM with a favourable cervix occurs more often in primiparous females, which is also coupled to peak rate complications. A 6-hour expectant management is considered as insufficient, because an onset of labor activity in 15.7 % of patients developed after latent period lasting more than 6 hours.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования: оценить особенности течения родов у пациенток с ПРПО при доношенной беременности и зрелой шейке матки. Материалы и методы. Проведен проспективный анализ течения родов и послеродового периода у 189 пациенток с одно плодной беременностью головным предлежанием, сроком беременности 37 нед и более, относящихся к низкой и умеренной группам риска, без противопоказаний к родам через естественные родовые пути. Как осложнение течения беременности, 89 из них имели дородовое излитие околоплодных вод (основная группа), и 100 рожениц вступили в роды с целым плодным пузырем (группа сравнения). Анализировались особенности течения родов. Результаты. В основной группе преобладали первородящие (66,7 %). Время от момента излития околоплодных вод до начала родовой деятельности составило у первородящих 4,15 ± 3,48 ч, у повторнородящих – 3,40 ± 2,13 ч, у 19 % рожениц за 6 ч безводного периода родовая деятельность не успевала развиться. Средняя продолжительность родов не зависела от паритета пациенток и была выше в группе с ПРПО: у первородящих – 8,06 ± 3,51 ч, в группе сравнения – 7,21 ± 2,56 ч (Т = –1,99; р = 0,04) за счет увеличения продолжительности первого периода родов. У пациенток с ПРПО и без ПРПО частота слабости родовой деятельности составляла 24,7 и 18,3 % (р = 0,29), дистоции шейки матки – 2,25 и 0 % (р = 0,13), применения окситоцина в родах – 35,9 и 18,3 % (р = 0,007). Процент операций кесарева сечения в основной группе составил 15 (16,85 %) случаев, вакуум-экстракций плода – 6 (6,74 %) случаев, в группе сравнения – по 2 (2,0 %) случая соответственно (χ2 = 16,13; р &lt; 0,001). Заключение. У пациенток с ПРПО и зрелой шейкой матки продолжительность родов, частота оперативного родоразрешения и случаев разрыва шейки матки, а также применения окситоцина значимо выше, чем при своевременном излитии околоплодных вод. ПРПО при зрелой шейке матки происходит чаще у первородящих и именно в этой группе сопряжено с максимальным числом осложнений. Выжидательная тактика в течение 6 ч недостаточна, у 15,7 % пациенток родовая деятельность развилась при безводном промежутке более чем через 6 ч.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>преждевременный разрыв плодных оболочек</kwd><kwd>кесарево сечение</kwd><kwd>аномалии родовой деятельности</kwd><kwd>слабость родовой деятельности</kwd><kwd>окситоцин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>premature rupture of membranes</kwd><kwd>cesarean section</kwd><kwd>labor abnormalities</kwd><kwd>labor weakness</kwd><kwd>oxytocin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tan B.P., Hannah M.E. Oxytocin for prelabour rupture of membranes at or near term. 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