akusherstvoObstetrics, Gynecology and ReproductionАкушерство, Гинекология и Репродукция2313-73472500-3194IRBIS LLC10.17749/2313-7347.116akusherstvo-692Research ArticleREVIEW ARTICLEНАУЧНЫЙ ОБЗОРPregnancy and Zika virusБеременность и вирус Зикаhttps://orcid.org/0000-0002-3634-7589СтарцеваТ. В.StartsevaT. V.

Старцева Татьяна Владимировна – студент 6-го курса педиатрического факультета

109004 Москва, ул. Земляной Вал, д. 62

Tatiana V. Startseva – 6th year Student, Faculty of Pediatrics

62 Str. Zemlyanoi Val, Moscow 109004

tanyastar001@mail.ruhttps://orcid.org/0000-0002-0437-5892КаншинаН. Н.KanshinaN. N.

Каншина Нина Николаевна – кандидат медицинских наук, доцент кафедры инфекционных болезней

109004 Москва, ул. Земляной Вал, д. 62

Nina N. Kanshina – MD, PhD, Associate Professor, Department of Infectious Diseases

62 Str. Zemlyanoi Val, Moscow 109004

ТретьяковаМ. В.TretyakovaM. V.

Третьякова Мария Владимировна – кандидат медицинских наук, врач акушер-гинеколог отделения гинекологии

119021 Москва, ул. Тимура Фрунзе, д. 15/1

Maria V. Tretyakova – MD, PhD, Obstetrician-Gynecologist, Department of Gynecology

15/1 Timura Frunze Str., Moscow 119021

https://orcid.org/0000-0001-8404-1042БицадзеВ. О.BitsadzeV. O.

Бицадзе Виктория Омаровна – доктор медицинских наук, профессор РАН, профессор кафедры акушерства и гинекологии Клинического института детского здоровья имени Н.Ф. Филатова

109004 Москва, ул. Земляной Вал, д. 62

Scopus Author ID: 6506003478

Researcher ID: F-8409-2017

Viktoria O. Bitsadze – MD, Dr Sci Med, Professor of RAS, Professor, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Scopus Author ID: 6506003478

Researcher ID: F-8409-2017

https://orcid.org/0000-0002-0725-9686ХизроеваД. Х.KhizroevaJ. Kh.

Хизроева Джамиля Хизриевна – доктор медицинских наук, профессор кафедры акушерства и гинекологии Клинического института детского здоровья имени Н.Ф. Филатова

109004 Москва, ул. Земляной Вал, д. 62

Scopus Author ID: 57194547147

Researcher ID: F-8384-2017

Jamilya Kh. Khizroeva – MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Scopus Author ID: 57194547147

Researcher ID: F-8384-2017

 

https://orcid.org/0000-0003-3410-6885РадецкаяЛ. С.RadetskayaL. S.

Радецкая Людмила Сергеевна – кандидат медицинских наук, доцент кафедры акушерства и гинекологии Клинического института детского здоровья имени Н.Ф. Филатова

109004 Москва, ул. Земляной Вал, д. 62

Liudmila S. Radetskaya – MD, PhD, Associate Professor, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

https://orcid.org/0000-0002-9454-9357СтулеваН. С.StulevaN. S.

Стулёва Надежда Сергеевна – кандидат медицинских наук, доцент кафедры акушерства и гинекологии Клинического института детского здоровья имени Н.Ф. Филатова

109004 Москва, ул. Земляной Вал, д. 62

Researcher ID: F-8694-2017

Nadezhda S. Stuleva – MD, PhD, Associate Professor, Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Researcher ID: F-8694-2017

 

https://orcid.org/0000-0001-5888-0774ЦибизоваВ. И.TsibizovaV. I.

Цибизова Валентина Ивановна – врач отделения функциональной и ультразвуковой диагностики

197341 Санкт-Петербург, ул. Аккуратова, д. 2

Valentina I. Tsibizova – MD, Department of Functional and Ultrasound Diagnostics

2 Akkuratova Str., Saint Petersburg 197341

https://orcid.org/0000-0002-9783-1796ШкодаА. С.ShkodaA. S.

Шкода Андрей Сергеевич – доктор медицинских наук, профессор, главный врач

123423 Москва, ул. Саляма Адиля, д. 2/44

Andrey S. Shkoda – MD, Dr Sci Med, Professor, Chief Physician

2/44 Salyama Adilya Str., Moscow 123423

https://orcid.org/0000-0002-3367-9844БлиновД. В.BlinovD. V.

Блинов Дмитрий Владиславович – кандидат медицинских наук, руководитель по медицинским и научным вопросам, Институт Превентивной и Социальной Медицины; врач-невролог, Клинический Госпиталь Лапино, ГК «Мать и Дитя»; преподаватель, кафедра неврологии, психиатрии и наркологии, АНО ДПО «Московский медико-социальный институт им. Ф.П. Гааза»

127006 Москва, ул. Садовая-Триумфальная, д. 4–10,143081 Московская область, Одинцовский район, Лапино, 1-е Успенское шоссе, д. 111,123056 Москва, 2-я Брестская улица, д. 5, стр. 1–1а

Researcher ID: E-8906-2017

RSCI: 9779-8290.

Dmitry V. Blinov – MD, PhD, MBA, Head of Medical and Scientific Affairs, Institute of Preventive and Social Medicine; Neurologist, Lapino Clinic Hospital, MD Medical Group; Faculty Member, Department of Neurology, Psychiatry and Narcology, Moscow Haass Medical–Social Institute

4–10 Sadovaya-Triumfalnaya Str., Moscow 127006,1st Uspenskoye Highway, 111, Moscow Region, Odintsovo District, Lapino 143081,5, 1–1a 2nd Brestskaya Str., Moscow 123056

Researcher ID: E-8906-2017

RSCI: 9779-8290

https://orcid.org/0000-0001-7415-4633МакацарияА. Д.MakatsariyaA. D.

Макацария Александр Давидович – доктор медицинских наук, академик РАН, профессор, заведующий кафедрой акушерства и гинекологии Клинического института детского здоровья имени Н.Ф. Филатова

109004 Москва, ул. Земляной Вал, д. 62

Scopus Author ID: 6602363216

Researcher ID: M-5660-2016.

Alexander D. Makatsariya – MD, Dr Sci Med, Professor, Academician of RAS, Head of the Department of Obstetrics and Gynecology, N.F. Filatov Clinical Institute of Children’s Health

62 Str. Zemlyanoi Val, Moscow 109004

Scopus Author ID: 6602363216

Researcher ID: M-5660-2016

ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияSechenov UniversityRussian FederationООО «Лечебный Центр»Россия«Medical Center» LLCRussian FederationФГБУ «Национальный медицинский исследовательский центр имени В.А. Алмазова» Министерства здравоохранения Российской ФедерацииРоссияAlmazov National Medical Research Centre, Health Ministry of Russian FederationRussian FederationГБУЗ «Городская клиническая больница № 67 имени Л.А. Ворохобова Департамента здравоохранения города Москвы»РоссияCity Clinical Hospital № 67 named after L.A. Vorokhobov, Moscow Healthcare DepartmentRussian FederationИнститут Превентивной и Социальной Медицины; Клинический Госпиталь Лапино, ГК «Мать и Дитя»; Автономная некоммерческая организация дополнительного профессионального образования «Московский медико-социальный институт имени Ф.П. Гааза»РоссияInstitute for Preventive and Social Medicine; Lapino Clinic Hospital, MD Medical Group; Moscow Haass Medical – Social InstituteRussian Federation202004062020142229238Copyright © Startseva T.V., Kanshina N.N., Tretyakova M.V., Bitsadze V.O., Khizroeva J.K., Radetskaya L.S., Stuleva N.S., Tsibizova V.I., Shkoda A.S., Blinov D.V., Makatsariya A.D., 20202020Старцева Т.В., Каншина Н.Н., Третьякова М.В., Бицадзе В.О., Хизроева Д.Х., Радецкая Л.С., Стулева Н.С., Цибизова В.И., Шкода А.С., Блинов Д.В., Макацария А.Д.Startseva T.V., Kanshina N.N., Tretyakova M.V., Bitsadze V.O., Khizroeva J.K., Radetskaya L.S., Stuleva N.S., Tsibizova V.I., Shkoda A.S., Blinov D.V., Makatsariya A.D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gynecology.su/jour/article/view/692

Zika virus (ZIKV) is an arthropod-borne virus (arbovirus) in the genus Flavivirus and the Flaviviridae family. In 1947 and 1948 ZIKV was first isolated from a nonhuman primate as well as from mosquitoes in Africa, respectively. For half a century, ZIKV infections in human were sporadic prior to 2015–2016 pandemic spreading. Transmission of ZIKV from mother to fetus can occur in any trimester of pregnancy, even if mother was an asymptomatic carrier. The clinical signs of ZIKV infection are nonspecific and can be misdiagnosed as some other infectious diseases, especially those caused by arboviruses such as Dengue and Chikungunya. ZIKV infection was solely associated with mild illness prior to the large French Polynesian and Brazil outbreaks, when severe neurological complications, Guillain–Barre syndrome and dramatically increased rate of severe congenital malformations (including microcephaly) were reported. The adaptation of ZIKV to an urban cycle in endemic areas suggests that the incidence of ZIKV infections may be underestimated. The pandemic of novel coronavirus infection (COVID-19) demonstrates that lessons from ZIKV pandemic propagation has not been learned properly.

Вирус Зика – это вирус, переносимый членистоногими (arbovirus) из рода Flavivirus, семейства Flaviviridae. Вирус Зика впервые был выделен у нечеловеческого примата в 1947 г. и у комаров в 1948 г. в Африке. Случаи инфекции, вызываемой вирусом Зика, были спорадическими в течение полувека, но в 2015–2016 гг. последовало пандемическое распространение. Передача вируса Зика от матери к плоду может происходить во всех триместрах беременности, даже если мать – бессимптомный носитель. Клинические проявления инфекции, вызываемой вирусом Зика, неспецифичны и могут быть неправильно диагностированы как другие инфекционные заболевания, особенно связанные с арбовирусами, такими как лихорадка Денге и Чикунгунья. Инфекция Зика ассоциировалась только с легкой формой заболевания до крупных вспышек во Французской Полинезии и Бразилии, когда сообщалось о тяжелых неврологических осложнениях, синдроме Гийена–Барре, а также о резком увеличении числа тяжелых врожденных пороков развития, включая микроцефалию. Адаптация вируса Зика к городскому циклу в эндемичных районах предполагает, что заболеваемость инфекцией Зика может быть недооценена. Пандемия новой коронавирусной инфекции (COVID-19) демонстрирует, что уроки пандемического распространения вируса Зика не были усвоены должным образом.

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The authors declare that there are no conflicts of interest present.