akusherstvoObstetrics, Gynecology and ReproductionАкушерство, Гинекология и Репродукция2313-73472500-3194IRBIS LLCakusherstvo-69Research ArticleREVIEW ARTICLEНАУЧНЫЙ ОБЗОРTHROMBOPHILIA AND THROMBOEMBOLIC COMPLICATIONS ASSOCIATED WITH USE OF ASSISTIVE REPRODUCTIVE TECHNOLOGIESТРОМБОФИЛИЯ И ТРОМБОЭМБОЛИЧЕСКИЕ ОСЛОЖНЕНИЯ, СВЯЗАННЫЕ С ИСПОЛЬЗОВАНИЕМ ВСПОМОГАТЕЛЬНЫХ РЕПРОДУКТИВНЫХ ТЕХНОЛОГИЙАкиньшинаС. В.AkinshinaS. V.svetlana_akin@mail.ruМакацарияА. Д.MakatsariyaA. D.БицадзеВ. О.BitsadzeV. O.СтулеваН. С.StulevaN. S.МашковаТ. Я.MashkovaT. Ya.ГБОУ ВПО «Первый МГМУ имени И.М. Сеченова» Минздрава РФ, МоскваРоссияFirst Moscow State Medical Sechenov University of the Ministry of Health Russian FederationRussian Federation201407062016828996Copyright © Akinshina S.V., Makatsariya A.D., Bitsadze V.O., Stuleva N.S., Mashkova T.Y., 20162016Акиньшина С.В., Макацария А.Д., Бицадзе В.О., Стулева Н.С., Машкова Т.Я.Akinshina S.V., Makatsariya A.D., Bitsadze V.O., Stuleva N.S., Mashkova T.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gynecology.su/jour/article/view/69

Thromboembolism represents the most serious, potentially fatal complication of assisted reproductive technologies and in most cases is associated with ovarian hyperstimulation syndrome. This article describes the modern aspects of the pathogenesis of ovarian hyperstimulation syndrome, the pathogenesis of thromboembolic complicationsand importance of genetic and acquired thrombophilia for their development, methods of risk assessment of thrombotic complications before using assisted reproductive technology and recommendations for prevention of thromboembolic complications in women enrolled in an IVF program.

Тромботические осложнения являются наиболее серьезными, потенциально смертельными осложнениями вспомогательных репродуктивных технологий, которые в большинстве случаев связаны с синдромом гиперстимуляции яичников. В статье описаны современные аспекты патогенеза синдрома гиперстимуляции яичников, патогенез тромбоэмболических осложнений и значение генетических и приобретенных тромбофилий для их развития, методики оценки факторов риска тромботических осложнений перед использованием вспомогательных репродуктивных технологий и рекомендации по профилактике тромбоэмболических осложнений у женщин, включенных в программы ЭКО.

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The authors declare that there are no conflicts of interest present.