akusherstvoObstetrics, Gynecology and ReproductionАкушерство, Гинекология и Репродукция2313-73472500-3194IRBIS LLC10.17749/2313-7347.2020.14.1.89-93akusherstvo-628Research ArticleCLINICAL CASESКЛИНИЧЕСКИЕ СЛУЧАИManagement of pregnancy and labor in female with combination of homozygous Leiden and heterozygous prothrombin G20210A mutationsВедение беременности и родов у женщины с сочетанной гомозиготной мутацией Лейдена и гетерозиготной формы протромбина G20210Ahttps://orcid.org/0000-0003-2515-4420АрсланбековаМ. О.ArslanbekovaM. O.

Мадина Османовна Арсланбекова - аспирант кафедры акушерства и гинекологии Клинического института детского здоровья имени Н.Ф. Филатова.

119991 Москва, ул. Трубецкая, д. 8, стр. 2

Madina O. Arslanbekova - Postgraduate Student, Department of Obstetrics and Gynecology.

Bild2,8 Trubetskaya St., Moscow 119991

amo05@bk.ruhttps://orcid.org/0000-0002-0725-9686ХизроеваД. Х.KhizroevaJ. Kh.

Джамиля Хизриевна Хизроева - доктор медицинских наук, профессор, профессор кафедры акушерства и гинекологии Клинического института детского здоровья имени Н.Ф. Филатова.

119991 Москва, ул. Трубецкая, д. 8, стр. 2

Jamilya Kh. Khizroeva - MD, Dr Sci Med, Professor, Department of Obstetrics and Gynecology.

Bild2,8 Trubetskaya St., Moscow 119991

ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияSechenov UniversityRussian Federation2020030420201418993Copyright © Arslanbekova M.O., Khizroeva J.K., 20202020Арсланбекова М.О., Хизроева Д.Х.Arslanbekova M.O., Khizroeva J.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gynecology.su/jour/article/view/628

Here we describe a clinical case of successfully managed pregnancy and labor in female with multigenic thrombophilia (combination of homozygous Leiden and heterozygous prothrombin G20210A mutations) associated with high risk of thrombosis by using proper anticoagulant therapy. It was underlined that females with obstetric complications should be examined for inherited and acquired types of thrombophilia.

В статье описан клинический случай успешного ведения беременности и родоразрешения женщины с мультигенной тромбофилией (сочетанием гомозиготной мутации Лейдена и гетерозиготной формы протромбина G20210A) с помощью адекватной антикоагулянтной терапии и подчеркивается важность исследования на наследственные и приобретенные формы тромбофилий при акушерских осложнениях.

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The authors declare that there are no conflicts of interest present.