<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347.2017.11.3.094-097</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-431</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group></article-categories><title-group><article-title>USEOFSODIUMBEMIPARININOBSTETRICPRACTICE. A CLINICAL CASE</article-title><trans-title-group xml:lang="ru"><trans-title>ПРИМЕНЕНИЕ БЕМИПАРИНА  НАТРИЯ В АКУШЕРСКОЙ ПРАКТИКЕ. КЛИНИЧЕСКИЙ ПРИМЕР. АКУШЕРСТВО, ГИНЕКОЛОГИЯ И РЕПРОДУКЦИЯ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хизроева</surname><given-names>Д. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Khizroeva</surname><given-names>D. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хизроева Джамиля Хизриевна –  доктор медицинских наук, профессор кафедры акушерства и гинекологии медико-профилактического факультета.</p><p>Ул. Земляной Вал, 62, стр. 1, Москва, 109004</p></bio><bio xml:lang="en"><p>Khizroeva  Dzhamilya  Hizrievna  – MD, Professor, Department of Obstetrics and Gynecology,  Faculty of Preventive Medicine.</p><p>Ul. Zemlyanoi val, 62, Moscow, 109004</p></bio><email xlink:type="simple">totu1@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Митрюк</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitryuk</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Митрюк Диана Викторовна – ассистент кафедры акушерства и гинекологии.</p><p>Бул. Штефан чел Маре, 165, Кишинев</p></bio><bio xml:lang="en"><p>Mitryuk Diana Viktorovna – assistant, Department of Obstetrics and Gynecology.</p><p>Bul. Shtefan chel Mare, 165, Kishinev</p></bio><email xlink:type="simple">diana.mitriuc@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет  имени  И.М. Сеченова» Министерства здравоохранения  Российской Федерации (Сеченовский Университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov  First Moscow State Medical University, Health Ministry of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Государственный медицинский и фармацевтический университет имени Николае Тестемицану</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Medical and Pharmaceutical  University «Nicolae Testemitanu»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>06</day><month>12</month><year>2017</year></pub-date><volume>11</volume><issue>3</issue><fpage>94</fpage><lpage>97</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Khizroeva D.K., Mitryuk D.V., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Хизроева Д.Х., Митрюк Д.В.</copyright-holder><copyright-holder xml:lang="en">Khizroeva D.K., Mitryuk D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/431">https://www.gynecology.su/jour/article/view/431</self-uri><abstract><p>The report presents a case of pregnancy management in a woman with a history of obstetric problems and neurosensory hearing loss. After thorough hemostasis tests, the presence of antiphospholipid antibodies in the blood was detected. Given a high risk of thrombophilia in this situation, the patient was treated with antithrombotic therapy – low molecular weight heparin (sodium bemiparin).</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлен клинический  пример ведения беременности у женщины с отягощенным акушерским  анамнезом и нейросенсорной потерей слуха. После тщательно проведенного обследования системы гемостаза была выявлена циркуляция антифосфолипидных антител. Учитывая тромбофилический характер изменений, пациентке была назначена  противотромботическая терапия – низкомолекулярный гепарин (бемипарин натрия).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антифосфолипидный синдром</kwd><kwd>тромбозы</kwd><kwd>нейросенсорная потеря слуха</kwd><kwd>бемипарин  натрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>antiphospholipid syndrome</kwd><kwd>thromboses</kwd><kwd>neurosensory hearing loss</kwd><kwd>sodium bemiparin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Khizroeva J., Kapanadze D., Andreeva M., Abramyan G. Antiphospholipid antibodies circulation and fetal loss syndrome. Papers and Abstracts of the 6th International Symposium on Women’s Health Issues in Thrombosis and Haemostasis. February 13-5. Berlin, Germany. Thromb Res. 2015: 51.</mixed-citation><mixed-citation xml:lang="en">Khizroeva J., Kapanadze D., Andreeva M., Abramyan G. Antiphospholipid  antibodies circulation and fetal loss syndrome. Papers and Abstracts of the 6th International Symposium on Women’s Health Issues in Thrombosis and Haemostasis. February 13-5. Berlin, Germany. Thromb Res. 2015: 51.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бицадзе В.О., Хизроева Д.Х., Идрисова Л.Э, Абрамян Р.Р., Андреева М.Д., Макацария А.Д. Катастрофический антифосфолипидный синдром. Вопросы патогенеза. Акушерство, гинекология и репродукция. 2015; 9 (2): 32-53.</mixed-citation><mixed-citation xml:lang="en">Bitsadze V.O., Khizroeva D.Kh., Idrisova L.E., Abramyan R.R., Andreeva M.D., Makatsaria A.D. Catastrophic antiphospholipid syndrome. Questions of pathogenesis [Katastroficheskij antifosfolipidnyj sindrom. Voprosy patogeneza]. Akusherstvo, ginekologiya i reprodukciya.  2015; 9 (2): 32-53 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Heilmann L., Rath W. Thrombophilia in pregnancy. Bremen, London, New York: Unimed. 2002.</mixed-citation><mixed-citation xml:lang="en">Heilmann L., Rath W. Thrombophilia in pregnancy. Bremen, London, New York: Unimed. 2002.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Lim W. Using low molecular weight heparin in special patient populations. J Thromb Thrombolysis. 2010; 29: 233-40.</mixed-citation><mixed-citation xml:lang="en">Lim W. Using low molecular weight heparin in special patient populations. J Thromb Thrombolysis. 2010; 29: 233-40.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Greer I.A., Nelson-Piercy C. Low-molecularweight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. Blood. 2005; 106 (2): 401-7.</mixed-citation><mixed-citation xml:lang="en">Greer I.A., Nelson-Piercy C. Low-molecularweight heparins for thromboprophylaxis and treatment of venous thromboembolism in pregnancy: a systematic review of safety and efficacy. Blood. 2005; 106 (2): 401-7.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Keeling D., Davidson S., Watson H. The management of heparin-induced thrombocytopenia. Br J Haematol. 2006; 133: 259-69.</mixed-citation><mixed-citation xml:lang="en">Keeling D., Davidson S., Watson H. The management  of heparin-induced thrombocytopenia.  Br J Haematol. 2006; 133: 259-69.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Baglin T., Barrowcliffe T.W., Cohen A., Greaves M. Guidelines on the use and monitoring of heparin. Br J Haematol. 2006; 133: 19-34.</mixed-citation><mixed-citation xml:lang="en">Baglin T., Barrowcliffe T.W., Cohen A., Greaves M. Guidelines on the use and monitoring of heparin. Br J Haematol. 2006; 133: 19-34.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Abbas M.S. Bemiparin versus Enoxaparin in the Prevention of Venous Thromboembolism among Intensive Care Unit Patients. Indian J Crit Care Med. 2017; 21 (7): 419-23. DOI: 10.4103/ijccm.IJCCM_23_17.</mixed-citation><mixed-citation xml:lang="en">Abbas M.S. Bemiparin versus Enoxaparin in the Prevention of Venous Thromboembolism among Intensive Care Unit Patients. Indian J Crit Care Med. 2017; 21 (7): 419-23. DOI: 10.4103/ijccm.IJCCM_23_17.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
