<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347.2016.10.4.105-113</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-379</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЙ ОБЗОР</subject></subj-group></article-categories><title-group><article-title>SURGICAL MENOPAUSE IN WOMEN OF REPRODUCTIVE AGE</article-title><trans-title-group xml:lang="ru"><trans-title>ХИРУРГИЧЕСКАЯ МЕНОПАУЗА У ЖЕНЩИН РЕПРОДУКТИВНОГО ВОЗРАСТА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулавский</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulavskii</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой акушерства и гинекологии ИДПО,</p><p>ул. Ленина, д. 3, Уфа, 450008</p></bio><bio xml:lang="en"><p>MD, Professor, head of Department of obstetrics and gynecology, Institute of additional professional education,</p><p>ul. Lenina, 3, Ufa, 450008</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кулавский</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulavskii</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры акушерства и гинекологии ИДПО,</p><p>ул. Ленина, д. 3, Уфа, 450008</p></bio><bio xml:lang="en"><p>PhD, associate professor of Department of obstetrics and gynecology, Institute of additional professional education,</p><p>ul. Lenina, 3, Ufa, 450008</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зиганшин</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ziganshin</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., ассистент кафедры акушерства и гинекологии ИДПО,</p><p>ул. Ленина, д. 3, Уфа, 450008</p></bio><bio xml:lang="en"><p>PhD, assistant of Department of obstetrics and gynecology, Institute of additional professional education,</p><p>ul. Lenina, 3, Ufa, 450008</p></bio><email xlink:type="simple">Zigaidar@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>10</day><month>03</month><year>2017</year></pub-date><volume>10</volume><issue>4</issue><fpage>105</fpage><lpage>113</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kulavskii V.A., Kulavskii E.V., Ziganshin A.M., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Кулавский В.А., Кулавский Е.В., Зиганшин А.М.</copyright-holder><copyright-holder xml:lang="en">Kulavskii V.A., Kulavskii E.V., Ziganshin A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/379">https://www.gynecology.su/jour/article/view/379</self-uri><abstract><p>The article represents peculiarities of the origination and treatment of surgical menopause at women of reproductive age, principles of monitoring and approaches to the hormonal therapy. In spite of the high efficiency of the therapy of menopausal disorders by estrogen containing substances there are diseases, for which its systemic administration is restricted. The supplement of the local therapy with physicotherapeutic influence in tissues allows to reduce the pain syndrome, to reduce the length of the treatment and to obtain the earlier restoration of the vagina mucous membrane.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлены особенности возникновения и лечения хирургической менопаузы у женщин репродуктивного возраста, принципы ведения и подходы к гормональной терапии. Несмотря на высокую эффективность терапии менопаузальных расстройств эстроген-содержащими препаратами существуют заболевания, при которых ограничено его системное назначение. Дополнение местной терапии физиотерапевтическим воздействием на ткани позволяет уменьшить болевой синдром, сократить продолжительность лечения и добиться более раннего восстановления слизистой влагалища.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хирургическая менопауза</kwd><kwd>овариоэктомия</kwd><kwd>менопаузальная гормональная терапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>surgical menopause</kwd><kwd>oophorectomy</kwd><kwd>menopausal hormone therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Блинов Д.В., Зимовина У.В., Сандакова Е.А., Ушакова Т.И. Дефицит магния у пациенток с гормонально-зависимыми заболеваниями: фармакоэпидемиологический профиль и оценка качества жизни. ФАРМАКОЭКОНОМИКА. Современная фармакоэкономика и фармакоэпидемиология. 2015; 8 (2): 16-24. DOI:10.17749/2070-4909.2015.8.2.016-024.</mixed-citation><mixed-citation xml:lang="en">Blinov D.V., Zimovina U.V., Sandakova E.A., Ushakova T.I. Magnesium deficiency of patients with hormone dependent diseases: pharmacoepidemiological profile and life quality assessment. PHARMACOECONOMICS. Modern pharmacoeconomics and pharmacoepidemiology. 2015;8(2): 16-24. (In Russ.) DOI:10.17749/2070-4909.2015.8.2.016-024</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Гинекологическая эндокринология (под ред. В.Н. Серова, В.Н. Прилепской, Г.В. Овсянниковой). М. 2015.</mixed-citation><mixed-citation xml:lang="en">Gynecological Endocrinology (ed. V. Serov VN Prilepskaya, GV Ovsyannikova) [Ginekologicheskaya endokrinologiya (pod red. V.N. Serova, V.N. Prilepskoi, G.V. Ovsyannikovoi) (in Russian)]. Moscow. 2015.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Зиганшин А.М., Фаткуллина И.Б. Эффективность вибромагнитного воздействия в лечении ран промежности у женщин, перенесших роды через естественные родовые пути. Лечение и профилактика. 2016; 2 (18): 5-10.</mixed-citation><mixed-citation xml:lang="en">Ziganshin A.M., Fatkullina I.B. Lechenie i profilaktika. 2016; 2 (18): 5-10.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Медицина климактерия (под ред. В.П. Сметник). Ярославль. 2006; 848 с.</mixed-citation><mixed-citation xml:lang="en">Menopause medicine (ed. Smetnik VP) [Meditsina klimakteriya (pod red. V.P. Smetnik) (in Russian)]. Yaroslavl'. 2006; 848 s.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Менопаузальная гормонотерапия и сохранение здоровья женщины зрелого возраста. Введение женщин в пери- и постменопаузе. Клинические рекомендации. М. 2014; 57 с.</mixed-citation><mixed-citation xml:lang="en">Menopausal hormone therapy and maintaining the health of a woman of mature age. The introduction of women in perimenopausal and postmenopausal women. Clinical guidelines. [Menopauzal'naya gormonoterapiya i sokhranenie zdorov'ya zhenshchiny zrelogo vozrasta. Vvedenie zhenshchin v peri- i postmenopauze. Klinicheskie rekomendatsii (in Russian)]. Moscow. 2014; 57 s.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Кулавский В.А., Зиганшин А.М. Влияние неблагоприятных факторов образа жизни на развитие несостоятельности мышц тазового дна и пролапса тазовых органов. Российский вестник акушера-гинеколога. 2009; 4 (9): 36-40.</mixed-citation><mixed-citation xml:lang="en">Kulavskii V.A., Ziganshin A.M. Rossiiskii vestnik akushera-ginekologa. 2009; 4 (9): 36-40.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Лихачев А.В., Галянская Е.Г., Шевлягина Л.С., Полянская И.Б. Терапия эстроген-дефицитных состояний в климактерическом периоде. Акушерство, гинекология, репродукция. 2008; 1: 4-6.</mixed-citation><mixed-citation xml:lang="en">Likhachev A.V., Galyanskaya E.G., Shevlyagina L.S., Polyanskaya I.B. Akusherstvo, ginekologiya i reproduktsiya / Obstetrics, gynecology and reproduction. 2008; 1: 4-6.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Набер К.Г., Бишоп М.С., Бйерклунд-Йохансен Т.Е. Рекомендации по ведению больных с инфекциями почек, мочевых путей и мужских половых органов – EAU. Смоленск. 2008; 224 c.</mixed-citation><mixed-citation xml:lang="en">Naber K.G., Bishop M.S., Bierklund-Iokhansen T.E. Recommendations for the management of patients with kidney infections, urinary tract and the male reproductive organs – EAU [Rekomendatsii po vedeniyu bol'nykh s infektsiyami pochek, mochevykh putei i muzhskikh polovykh organov – EAU (in Russian)]. Smolensk. 2008; 224 c.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Невмержицкая И.Ю., Хамошина М.Б., Плаксина Н.Д., Погасов А.Г. Факторы риска и прогноз формирования остеопенического синдрома у женщин в перименопаузе. Печ. Вестник РУДН. 2009; 5: 101-107.</mixed-citation><mixed-citation xml:lang="en">Nevmerzhitskaya I.Yu., Khamoshina M.B., Plaksina N.D., Pogasov A.G. Pech. Vestnik RUDN. 2009; 5: 101-107.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Овсянникова О.В., Куликов И.А. Принципы назначения монотерапии эстрогенами. Медицинский совет. 2015; 9: 66-70.</mixed-citation><mixed-citation xml:lang="en">Ovsyannikova O.V., Kulikov I.A. Meditsinskii sovet. 2015; 9: 66-70.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Овсянникова Т.В., Макаров И.О., Куликов И.А. Клиническая эффективность негормональных методов терапии у женщин в перименопаузе. Акушерство, гинекология репродукция. 2013; 3: 26-29.</mixed-citation><mixed-citation xml:lang="en">Ovsyannikova T.V., Makarov I.O., Kulikov I.A. Akusherstvo, ginekologiya i reproduktsiya / Obstetrics, gynecology and reproduction. 2013; 3: 26-29.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Пан Ги Мун. Послание по случаю Международного дня пожилых людей. URL: http: // www.un.org/ru/sg/messages/2016/olderpersonsday.shtml. Дата обращения: 28.09.2016.</mixed-citation><mixed-citation xml:lang="en">Pan Gi Mun. Message on the International Day of Older Persons [Poslanie po sluchayu Mezhdunarodnogo dnya pozhilykh lyudei (in Russian)]. URL: http: // www.un.org/ru/sg/messages/2013/olderpersobsday.shtml. Accessed: 28.09.2016.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Плаксина Н.Д., Симоновская Х.Ю. Возможности негормональной коррекции вазомоторных пароксизмов в постменопаузе. Status Praesens. 2014; 2(19); 60-65.</mixed-citation><mixed-citation xml:lang="en">Plaksina N.D., Simonovskaya Kh.Yu. Status Praesens. 2014; 2(19); 60-65.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Пономаренко Г.Н. Физиотерапия: национальное руководство. М. 2009; 864 с.</mixed-citation><mixed-citation xml:lang="en">Ponomarenko G.N. Physiotherapy: national leadership [Fizioterapiya: natsional'noe rukovodstvo (in Russian)]. Moscow. 2009; 864 s.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Практические рекомендации. Ведение женщин в пери- и в постменопаузе. Под ред. В.П. Сметник. М. 2010; 221 с.</mixed-citation><mixed-citation xml:lang="en">Practical recommendations. Keeping women in the peri- and post-menopausal. Ed. VP Smetnik [Prakticheskie rekomendatsii. Vedenie zhenshchin v peri- i v postmenopauze. Pod red. V.P. Smetnik (in Russian)]. Moscow. 2010; 221 s.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Радзинский В.Е., Хамошина М.Б., Мельникова Г.Г. Современный подход к терапии и профилактике метаболических нарушений, связанных с хирургической менопаузой. Доктор. Ру. 2009; 6 (50): 21-27.</mixed-citation><mixed-citation xml:lang="en">Radzinskii V.E., Khamoshina M.B., Mel'nikova G.G. Doktor. Ru. 2009; 6 (50): 21-27.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Салов И.А., Хашаева Т.Х., Дуганова М.О. и др. Вибромагнитный массаж и ионофорез в терапии хронического цистита у женщин в постменопаузе. Акушерство и гинекология. 2010; 6: 65-68.</mixed-citation><mixed-citation xml:lang="en">Salov I.A., Khashaeva T.Kh., Duganova M.O. i dr. Akusherstvo i ginekologiya. 2010; 6: 65-68.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Сметник В.П., Ильина Л.М. Роль половых гормонов в развитии метаболических расстройств у женщин в пери- и ранней постменопаузе. Климактерий. 2009; 1: 8-13.</mixed-citation><mixed-citation xml:lang="en">Smetnik V.P., Il'ina L.M. Klimakterii. 2009; 1: 8-13.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Хамошина М.Б., Мельникова Г.Г., Невмержицкая И.Ю. Правила «противопожарной безопасности» (Менопаузальный метаболический синдром в практике акушера-гинеколога). Status Praesens. 2009; 1 (2): 63-71.</mixed-citation><mixed-citation xml:lang="en">Khamoshina M.B., Mel'nikova G.G., Nevmerzhitskaya I.Yu. Status Praesens. 2009; 1 (2): 63-71.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Юренева С.Р., Дубровина А.В. Климактерический синдром. Medica mente. 2015; 1: 26-34.</mixed-citation><mixed-citation xml:lang="en">Yureneva S.R., Dubrovina A.V. Medica mente. 2015; 1: 26-34.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Assessment and management of cardiovascular risks in women. URL: http// www.imsociety.org/downloads/assessment-and-management-ofcardiovascular-risks-in-women/english.pdf. Дата обращения: 28.09.2016.</mixed-citation><mixed-citation xml:lang="en">Assessment and management of cardiovascular risks in women. URL: http// www.imsociety.org/downloads/assessment-and-management-ofcardiovascular-risks-in-women/english.pdf. Accessed: 28.09.2016.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Al.-Boghdadi O., Ewies A.A. Topical estrogen therapy in the management of postmenopausal vaginal atrophy: an up-to-date overviev. Climacteric. 2009; 12 (2): 91-105.</mixed-citation><mixed-citation xml:lang="en">Al.-Boghdadi O., Ewies A.A. Topical estrogen therapy in the management of postmenopausal vaginal atrophy: an up-to-date overviev. Climacteric. 2009; 12 (2): 91-105.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Buhling K.J., Daniels B.V., Studnitz F.S. et al. The use complementary and alternative medicine by women transitioning through menopause in Germany: results of a survey of women aged 45-60 years. Complement Ther. Med. 2014; 22 (1): 94-98.</mixed-citation><mixed-citation xml:lang="en">Buhling K.J., Daniels B.V., Studnitz F.S. et al. The use complementary and alternative medicine by women transitioning through menopause in Germany: results of a survey of women aged 45-60 years. Complement Ther. Med. 2014; 22 (1): 94-98.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ceylan B., Ozerdogan N. Menopausal symptoms and guality of life in Turkish women in the climacteric period. Climacteric. 2014; 1-18.</mixed-citation><mixed-citation xml:lang="en">Ceylan B., Ozerdogan N. Menopausal symptoms and guality of life in Turkish women in the climacteric period. Climacteric. 2014; 1-18.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Calleia-Agius J., Brincat M.P., Urogenital atrophy. Climacteric. 2009; 12 (4); 275-285.</mixed-citation><mixed-citation xml:lang="en">Calleia-Agius J., Brincat M.P., Urogenital atrophy. Climacteric. 2009; 12 (4); 275-285.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Chlebowski R.T., Anderson G.L., Menopausal hormone therapy and cancer: Changing clinical observations of target site specificity. Steroids. 2014; 14: 125-131.</mixed-citation><mixed-citation xml:lang="en">Chlebowski R.T., Anderson G.L., Menopausal hormone therapy and cancer: Changing clinical observations of target site specificity. Steroids. 2014; 14: 125-131.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Cody J.D., Richardson K., Moehrer B., Hextall A., Glazener C.M. Oestrogen therapy for urinary incontinence in post-menopausal women. Cochrane Database Syst Rev. 2009; 7 (4).</mixed-citation><mixed-citation xml:lang="en">Cody J.D., Richardson K., Moehrer B., Hextall A., Glazener C.M. Oestrogen therapy for urinary incontinence in post-menopausal women. Cochrane Database Syst Rev. 2009; 7 (4).</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Cornu J.N., Merlet B., Cussenot O., Cancel-Tassin G., Amarenco G., Haab F. Genetic susceptibility to urinary incontinence: implication of polymorphisms of androgen and oestrogen pathways. World J Urol. 2011; 29 (2): 239-242.</mixed-citation><mixed-citation xml:lang="en">Cornu J.N., Merlet B., Cussenot O., Cancel-Tassin G., Amarenco G., Haab F. Genetic susceptibility to urinary incontinence: implication of polymorphisms of androgen and oestrogen pathways. World J Urol. 2011; 29 (2): 239-242.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">G.K.P., Arounassalame B The guality of life during and after menopause among rural women. J. Clin. Diagn. Res. 2013; 7 (1): 135-139.</mixed-citation><mixed-citation xml:lang="en">G.K.P., Arounassalame B The guality of life during and after menopause among rural women. J. Clin. Diagn. Res. 2013; 7 (1): 135-139.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Herber-Gast G.-C.M., Mishra G.D. Early severe vasomotor menopausal symptoms are associated with diabetes. Menopause. 2014; 21 (8): 167-172.</mixed-citation><mixed-citation xml:lang="en">Herber-Gast G.-C.M., Mishra G.D. Early severe vasomotor menopausal symptoms are associated with diabetes. Menopause. 2014; 21 (8): 167-172.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Moreira A.C., Silva A.M., Santos M.S., Sardao V.A. Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown. J. Steroid Biochem Mol. Biol. 2014; 28 (143): 61-71.</mixed-citation><mixed-citation xml:lang="en">Moreira A.C., Silva A.M., Santos M.S., Sardao V.A. Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown. J. Steroid Biochem Mol. Biol. 2014; 28 (143): 61-71.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Mujeeb F., Bajpai P., Pathak N. Phytochemical Evaluation, Antimicrobial Activity, and Determination of Bioactive Components from Leaves of Aegle marmelos. Biomed Res Int. 2014; 29 (144): 45-49.</mixed-citation><mixed-citation xml:lang="en">Mujeeb F., Bajpai P., Pathak N. Phytochemical Evaluation, Antimicrobial Activity, and Determination of Bioactive Components from Leaves of Aegle marmelos. Biomed Res Int. 2014; 29 (144): 45-49.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Nisar N., Sohoo N.A. Freguency of menopausal symptoms and impact on the guality of life of women:a hospital based survey. J. Pac Med. Assoc. 2009; 59 (11): 752-756.</mixed-citation><mixed-citation xml:lang="en">Nisar N., Sohoo N.A. Freguency of menopausal symptoms and impact on the guality of life of women:a hospital based survey. J. Pac Med. Assoc. 2009; 59 (11): 752-756.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Ohmichi M., Tasaka k.et al. Molecular mechanism of action of Selective Estrogen Receptor Modulator in target tissues. J. Endocr. 2005; 52 (2): 161-167.</mixed-citation><mixed-citation xml:lang="en">Ohmichi M., Tasaka k.et al. Molecular mechanism of action of Selective Estrogen Receptor Modulator in target tissues. J. Endocr. 2005; 52 (2): 161-167.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Pitkin J. Alternative and complementary therapies for the menopause. Menopause Int. 2012; 18 (1): 20-27.</mixed-citation><mixed-citation xml:lang="en">Pitkin J. Alternative and complementary therapies for the menopause. Menopause Int. 2012; 18 (1): 20-27.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Raz R., Stamm W. E. A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. New Engl. J. Med. 1993; 329: 753-6.</mixed-citation><mixed-citation xml:lang="en">Raz R., Stamm W. E. A controlled trial of intravaginal estriol in postmenopausal women with recurrent urinary tract infections. New Engl. J. Med. 1993; 329: 753-6.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Santen R.J. et al. Endocrine Society. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J. Clin. Endocrinol. Metab. 2010; 95 (71): 346-352.</mixed-citation><mixed-citation xml:lang="en">Santen R.J. et al. Endocrine Society. Postmenopausal hormone therapy: an Endocrine Society scientific statement. J. Clin. Endocrinol. Metab. 2010; 95 (71): 346-352.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Sood R., Faubion S.S., Kuhle C.L. et al. Prescribing menopausal hormone therapy: an evidence-based approach. Int. J. Womens Health. 2014; 6: 47-57.</mixed-citation><mixed-citation xml:lang="en">Sood R., Faubion S.S., Kuhle C.L. et al. Prescribing menopausal hormone therapy: an evidence-based approach. Int. J. Womens Health. 2014; 6: 47-57.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Tsai S.A., Stefanick M.L., Stafford R.S. Trends in menopausal hormone therapy use of US office based physicians, 2000-2009. Menopause. 2011; 8: 385-392.</mixed-citation><mixed-citation xml:lang="en">Tsai S.A., Stefanick M.L., Stafford R.S. Trends in menopausal hormone therapy use of US office based physicians, 2000-2009. Menopause. 2011; 8: 385-392.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Villiers T.J., Gass M.L.S., Haines C.J. Global Consensus Statement on Menopausal Hormone Therapy. Climacteric. 2013; 16: 203-204.</mixed-citation><mixed-citation xml:lang="en">Villiers T.J., Gass M.L.S., Haines C.J. Global Consensus Statement on Menopausal Hormone Therapy. Climacteric. 2013; 16: 203-204.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
