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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-320</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GYNECOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>ANALYSIS OF RISK FACTORS OF THE STRESS URINARY INCONTINENCE IN WOMEN</article-title><trans-title-group xml:lang="ru"><trans-title>АНАЛИЗ ФАКТОРОВ РИСКА РАЗВИТИЯ СТРЕССОВОГО НЕДЕРЖАНИЯ МОЧИ У ЖЕНЩИН</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдеева</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdeeva</surname><given-names>D. M.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балан</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Balan</surname><given-names>V. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трофимов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Donnikov</surname><given-names>A. E.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Донников</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Trofimov</surname><given-names>D. Y.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Научный центр акушерства, гинекологии и перинатологии им. В.И. Кулакова» Минздравсоцразвития России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Academician V. I. Kulakov Research Center of Obstetrics, Gynecology and Perinatology, Ministry of Health and Social Development of the Russian Federation, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>06</day><month>09</month><year>2016</year></pub-date><volume>6</volume><issue>2</issue><fpage>41</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Abdeeva D.M., Balan V.E., Donnikov A.E., Trofimov D.Y., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Абдеева Д.М., Балан В.Е., Трофимов Д.Ю., Донников А.Е.</copyright-holder><copyright-holder xml:lang="en">Abdeeva D.M., Balan V.E., Donnikov A.E., Trofimov D.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/320">https://www.gynecology.su/jour/article/view/320</self-uri><abstract><p>Objective. Identification and analysis of risk factors for stress urinary incontinence in women, assessing the relationship of stress urinary incontinence and undifferentiated connective tissue dysplasia. Subjects and methods. The study group included 85 women with a confirmed diagnosis of stress urinary incontinence, in the control group - 105 women without disease, comparable to the main features of the study group. We used clinical-anamnestic method of investigation, questioning (ICIQ-SF), a comprehensive urodynamic study. Evaluation of genital prolapse was conducted to quantity the classification of pelvic organ prolaps (POP-Q), assessment of severity of the connective tissue dysplasia was carried out on a scale of severity of the clinical criteria for connective tissue dysplasia, modified by Buyanova and Smolnova. Results. We established elevated risk of stress urinary incontinence in women with a BMI value of 30 kg/m 2, RR = 2,45 (95% Cl 1,21-4,94, p&lt;0,05), as well as in the group of patients, with a history of major birth fetus through the birth canal, RR = 3,67 (95% Cl 1,39-9,69, p&lt;0,005) and with a history of hysterectomy without adnexa (RR = 11,01, 95% Cl 1,42-85,2, p&lt;0,05 ) Genetic predisposition, hard physical labor, hypertensive disease with regular intake of antihypertensive drugs drugs with a diuretic effect, osteoporosis and obesity play an important role in the development of stress urinary incontinence. A statistically significant increased risk of stress urinary incontinence were detected in the group with an average weight of connective tissue dysplasia (RR = 11,62, 95% CI 4,32-31,27, p&lt;0,002), the most important features of wich were hypermotility of joints and the tendency to dislocation, varicose veins and hemorrhoids, hernia, prolapse and visceroptosia genatalia in close relatives. Conclusion. We found a clear association between stress urinary incontinence and connective tissue dysplasia, identified major risk factors for the disease.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования. Выявление и анализ факторов риска развития стрессового недержания мочи у женщин, оценка взаимосвязи стрессового недержания мочи и недифференцированной дисплазии соединительной ткани (нДСТ). Материал и методы. В основную группу были включены 85 женщин с подтвержденным диагнозом стрессового недержания мочи, в группу контроля - 105 женщин без данного заболевания, сопоставимые по основным признакам с основной группой. Применяли клинико-анамнестический метод исследования, анкетирование (ICIQ-SF), комплексное уродинамическое исследование. Оценка степени пролапса гениталий проводилась по количественной классификации пролапса тазовых органов POP-Q, оценка степени тяжести дисплазии соединительной ткани проводилась по шкале клинических критериев выраженности ДСТ, модифицированной С.Н. Буяновой и Т.Ю. Смольновой. Результаты исследования. Установлено повышение риска возникновения СНМ в группе женщин с величиной ИМТ более 30 кг/м 2, RR = 2,45 (95% д. и. 1,21-4,94; р&lt;0,05), а также в группе пациенток, имеющих в анамнезе роды крупным плодом через естественные родовые пути, RR = 3,67 (95% д. и. 1,39 - 9,69, р&lt;0,005) и имеющих в анамнезе гистерэктомию без придатков (RR = 11,01 (95% д. и. 1,42 - 85,2, р&lt;0,05). Важную роль в развитии стрессового недержания мочи играют наследственная предрасположенность, тяжелый физический труд, гипертоническая болезнь с систематическим приемом антигипертензивных средств с диуретическим эффектом, остеопороз и ожирение. Статистически значимое повышение риска развития СНМ выявлялось в группе со средней тяжестью нДСТ (RR = 11,62 (95% д. и. 4,32 - 31,27, р&lt;0,002), наиболее важными признаками которой являлись гиперподвижность суставов и склонность к вывихам, варикозная болезнь и геморрой, грыжи, спланхноптоз и пролапс гениталий у близких родственников. Заключение. Выявлена четкая ассоциация между стрессовым недержанием мочи и нДСТ, определены ведущие факторы риска развития данной патологии.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стрессовое недержание мочи</kwd><kwd>недифференцированная дисплазия соедини- тельной ткани</kwd><kwd>нДСТ</kwd><kwd>факторы риска</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аполихина И.А., Константинов В.В., Деев А.Д. Распространенность и социальные аспекты недержания мочи у женщин. Акуш. и гин. 2005; 5: 32-6.</mixed-citation><mixed-citation xml:lang="en">Аполихина И.А., Константинов В.В., Деев А.Д. Распространенность и социальные аспекты недержания мочи у женщин. Акуш. и гин. 2005; 5: 32-6.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ковалева Л.А., Балан В.Е., Гончаревская З.Л. Оценка нарушений мочеиспускания у беременных женщин. Акушерство и гинекология, 2009; 3: стр. 55-58</mixed-citation><mixed-citation xml:lang="en">Ковалева Л.А., Балан В.Е., Гончаревская З.Л. Оценка нарушений мочеиспускания у беременных женщин. Акушерство и гинекология, 2009; 3: стр. 55-58</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Лоран О.Б. Эпидемиология, этиология, патогенез, диагностика недержания мочи: Матер. Пленума Правления Рос. общества урологов. М. 2001; 21-41.</mixed-citation><mixed-citation xml:lang="en">Лоран О.Б. Эпидемиология, этиология, патогенез, диагностика недержания мочи: Матер. Пленума Правления Рос. общества урологов. М. 2001; 21-41.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Altaweel W., Alharbi M. Urinary incontinence: Prevalence, risk factors, and impact on health related quality of life in Saudi women. Neurourol Urodyn. 2012 Mar 13 DOI: 10.1002/nau.22201</mixed-citation><mixed-citation xml:lang="en">Altaweel W., Alharbi M. Urinary incontinence: Prevalence, risk factors, and impact on health related quality of life in Saudi women. Neurourol Urodyn. 2012 Mar 13 DOI: 10.1002/nau.22201</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Duru C., Jha S., Lashen H. Urodynamic outcomes after hysterectomy for benign conditions: A systematic review and metaanalysis. Obstet Gynecol Surv. 2012 Jan; 67(1): 45-54.</mixed-citation><mixed-citation xml:lang="en">Duru C., Jha S., Lashen H. Urodynamic outcomes after hysterectomy for benign conditions: A systematic review and metaanalysis. Obstet Gynecol Surv. 2012 Jan; 67(1): 45-54.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hannestad Y.S., Rortveit G., Sandvik H., Hunskaar S. Epidemiology of Incontinence in the County of Nord-Trndelag. A community-based epidemiological survey of female urinary incontinence: the Norwegian EPINCONT study. J. Clin Epidemiol. 2000 Nov; 53(11): 1150-7.</mixed-citation><mixed-citation xml:lang="en">Hannestad Y.S., Rortveit G., Sandvik H., Hunskaar S. Epidemiology of Incontinence in the County of Nord-Trndelag. A community-based epidemiological survey of female urinary incontinence: the Norwegian EPINCONT study. J. Clin Epidemiol. 2000 Nov; 53(11): 1150-7.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kondo A., Narushima M., Yoshikawa Y., Hayashi H. Pelvic fascia strength in women with stress urinary incontinence in comparison with those who are continent. Neurourol Urodyn. 2005 Oct DOI: DOI: 10.1002/nau.1930130502</mixed-citation><mixed-citation xml:lang="en">Kondo A., Narushima M., Yoshikawa Y., Hayashi H. Pelvic fascia strength in women with stress urinary incontinence in comparison with those who are continent. Neurourol Urodyn. 2005 Oct DOI: DOI: 10.1002/nau.1930130502</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Stothers L., Friedman B. Risk factors for the development of stress urinary incontinence in women. Curr Urol Rep. 2011 Oct; 12(5): 363-9.</mixed-citation><mixed-citation xml:lang="en">Stothers L., Friedman B. Risk factors for the development of stress urinary incontinence in women. Curr Urol Rep. 2011 Oct; 12(5): 363-9.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Sykes D., Castro R., Pons M.E., Hampel C. Characteristics of female outpatients with urinary incontinence participating in a 6-month observational study in 14 European countries. Maturitas. 2005 Nov 30; 52.</mixed-citation><mixed-citation xml:lang="en">Sykes D., Castro R., Pons M.E., Hampel C. Characteristics of female outpatients with urinary incontinence participating in a 6-month observational study in 14 European countries. Maturitas. 2005 Nov 30; 52.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Tennstedt S.L., Fitzgerald M.P. et al. Quality of life in women with stress urinary incontinence. Int Urogynecol J. Pelvic Floor Dysfunct. 2007 May; 18(5): 543-9.</mixed-citation><mixed-citation xml:lang="en">Tennstedt S.L., Fitzgerald M.P. et al. Quality of life in women with stress urinary incontinence. Int Urogynecol J. Pelvic Floor Dysfunct. 2007 May; 18(5): 543-9.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Thibault, Bart S., Ciangura C., Cardot V., Richard F., Basdevant A., Chartier-Kastler E.F. Stress urinary incontinence and obesity. Prog Urol. 2008 Sep; 18(8): 493-8.</mixed-citation><mixed-citation xml:lang="en">Thibault, Bart S., Ciangura C., Cardot V., Richard F., Basdevant A., Chartier-Kastler E.F. Stress urinary incontinence and obesity. Prog Urol. 2008 Sep; 18(8): 493-8.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Ulmsten U., Falconer C. Connective tissue in female urinary incontinence. Curr Opin Obstet Gynecol. 1999 Oct; 11(5): 509-15.</mixed-citation><mixed-citation xml:lang="en">Ulmsten U., Falconer C. Connective tissue in female urinary incontinence. Curr Opin Obstet Gynecol. 1999 Oct; 11(5): 509-15.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Waetjen L.E., Ye J., Feng W.Y., Johnson W.O., Greendale G.A., Sampselle C.M., Sternfield B., Harlow S.D., Gold E.B.; Study of Women’s Health Across the Nation (SWAN). Association between menopausal transition stages and developing urinary incontinence. Obstet Gynecol. 2009 Nov; 114(5): 989-98.</mixed-citation><mixed-citation xml:lang="en">Waetjen L.E., Ye J., Feng W.Y., Johnson W.O., Greendale G.A., Sampselle C.M., Sternfield B., Harlow S.D., Gold E.B.; Study of Women’s Health Across the Nation (SWAN). Association between menopausal transition stages and developing urinary incontinence. Obstet Gynecol. 2009 Nov; 114(5): 989-98.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
