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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347.2016.10.2.064-069</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-295</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW ARTICLE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЙ ОБЗОР</subject></subj-group></article-categories><title-group><article-title>MANAGEMENT OF PATIENTS WITH CERVICAL INSUFFICIENCY</article-title><trans-title-group xml:lang="ru"><trans-title>ВЕДЕНИЕ ПАЦИЕНТОК С ИСТМИКО-ЦЕРВИКАЛЬНОЙ НЕДОСТАТОЧНОСТЬЮ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Леваков</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Levakov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, заведующий кафедрой акушерства и гинекологии ИПО,</p><p>ул. Трубецкая, 8, стр. 2, Москва, 119048</p></bio><bio xml:lang="en"><p>MD, Professor, Head of the Department of Obstetrics and Gynecology IPO,</p><p>ul. Trubetskaya, 8, p. 2, Moscow, 119048</p></bio><email xlink:type="simple">Levakoff@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боровкова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Borovkova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры акушерства и гинекологии ИПО,</p><p>ул. Трубецкая, 8, стр. 2, Москва, Россия, 119048</p></bio><bio xml:lang="en"><p>MD, Professor, Department of Obstetrics and Gynecology IPO,</p><p>ul. Trubetskaya, 8, p. 2, Moscow, 119048</p></bio><email xlink:type="simple">Katyanikitina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шешукова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheshukova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор кафедры акушерства и гинекологии ИПО,</p><p>ул. Трубецкая, 8, стр. 2, Москва, 119048</p></bio><bio xml:lang="en"><p>MD, Professor, Department of Obstetrics and Gynecology IPO,</p><p>ul. Trubetskaya, 8, p. 2, Moscow, 119048</p></bio><email xlink:type="simple">dr.sheshukova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боровков</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Borovkov</surname><given-names>I. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>студент,</p><p>ул. Трубецкая, 8, стр. 2, Москва, 119048</p></bio><bio xml:lang="en"><p>student,</p><p>ul. Trubetskaya, 8, p. 2, Moscow, 119048</p></bio><email xlink:type="simple">bigchanc97@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Первый МГМУ имени И.М. Сеченова» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Moscow State Medical Sechenov University of the Ministry of Health Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2016</year></pub-date><volume>10</volume><issue>2</issue><fpage>64</fpage><lpage>69</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Levakov S.A., Borovkova E.I., Sheshukova N.A., Borovkov I.M., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Леваков С.А., Боровкова Е.И., Шешукова Н.А., Боровков И.М.</copyright-holder><copyright-holder xml:lang="en">Levakov S.A., Borovkova E.I., Sheshukova N.A., Borovkov I.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/295">https://www.gynecology.su/jour/article/view/295</self-uri><abstract><p>The article presents a literature review on methods of diagnosis, therapy and management of patients with isthmic-cervical insufficiency. Risk factors for the development of isthmic-cervical insufficiency are the acquired and congenital anomalies of the cervix. The diagnosis can be made only during pregnancy. Shortening of cervical length &lt;25 mm before 24 weeks indicates the presence of ICN and the significant risk of miscarriage. Initial evaluation of the cervical length is from 14 weeks. When finding a shortening of the length of the closed part of the cervical canal is less than 25 mm the treatment of choice is surgical correction. When the cervical length more than 25 mm prophylactically from 19 to 32 weeks assigned to micronized progesterone 200 mg vagina. In identifying ICN after 24 weeks, the method of choice is the appointment of micronized progesterone and the installation of an unloading obstetric pessary. The use of a differentiated algorithm of management of patients with ICN reduces the chance of unexpected premature birth and neonatal morbidity and mortality.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлен обзор литературы, посвященный методам диагностики, терапии и тактики ведения пациенток с истмико-цервикальной недостаточностью (ИЦН). Факторами риска развития истмико-цервикальной недостаточности являются приобретенные и врожденные аномалии шейки матки. Диагноз может быть поставлен только во время беременности. Укорочение длины шейки матки &lt;25 мм до 24 нед. свидетельствует о наличии ИЦН и значимом риске невынашивания беременности. Первичная оценка длины шейки матки проводится с 14 нед. При выявлении укорочения длины сомкнутой части цервикального канала менее 25 мм методом выбора является хирургическая коррекция и вагинальный прогестерон. При выявлении ИЦН в сроки после 24 нед. методом выбора является назначение микронизированного прогестерона и установка разгрузочного акушерского пессария. Применение дифференцированного алгоритма ведения пациенток с ИЦН снижает вероятность неожиданных преждевременных родов и неонатальной заболеваемости и смертности.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>истмико-цервикальная недостаточность</kwd><kwd>преждевременные роды</kwd><kwd>невынашивание беременности</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>isthmic-cervical insufficiency</kwd><kwd>preterm labor</kwd><kwd>miscarriage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Приказ Минздрава России от 12 ноября 2012 г. № 572н «Об утверждении Порядка оказания медицинской помощи по профилю «акушерство и гинекология (за исключением использования вспомогательных репродуктивных технологий)». URL: https://www.rosminzdrav.ru/documents/5828-prikaz. 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