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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-288</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GYNECOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>EFFECTS OF PREGNANCY ON THE PROGRESSION OF METABOLIC SYNDROME COMPONENTS</article-title><trans-title-group xml:lang="ru"><trans-title>ВЛИЯНИЕ БЕРЕМЕННОСТИ НА ПРОГРЕССИРОВАНИЕ КОМПОНЕНТОВ МЕТАБОЛИЧЕСКОГО СИНДРОМА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>И. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>I. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра акушерства и гинекологии ФППОВ</p></bio><bio xml:lang="en"><p>Chair of Obstetrics and Gynaecology, Faculty for Continuous Training and Postgraduate Education of Physicians</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шилов</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Shilov</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра нефрологии и гемодиализа ФППОВ</p></bio><bio xml:lang="en"><p>Chair of Nephrology and Haemodialysis, Faculty for Continuous Training and Postgraduate Education of Physicians</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра эндокринологии ФППОВ</p></bio><bio xml:lang="en"><p>Chair of Endocrinology, Faculty for Continuous Training and Postgraduate Education of Physicians</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боровкова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Borovkova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра акушерства и гинекологии ФППОВ</p></bio><bio xml:lang="en"><p>Chair of Obstetrics and Gynaecology, Faculty for Continuous Training and Postgraduate Education of Physicians</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МГМУ им. И.М. Сеченова Минздравсоцразвития России, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budget-Funded Educational Establishment First Moscow State Medical University named after I. M. Sechenov of the Ministry of Health and Social Development of the Russian Federation, Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>02</day><month>09</month><year>2016</year></pub-date><volume>5</volume><issue>4</issue><fpage>20</fpage><lpage>26</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Makarov I.O., Shilov E.M., Novikova M.S., Borovkova E.I., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Макаров И.О., Шилов Е.М., Новикова М.С., Боровкова Е.И.</copyright-holder><copyright-holder xml:lang="en">Makarov I.O., Shilov E.M., Novikova M.S., Borovkova E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/288">https://www.gynecology.su/jour/article/view/288</self-uri><abstract><p>The article presents the results of a prospective cohort study that investigated changes in principal components of the metabolic syndrome (MS) in women in the course of a pregnancy and an assessment of these components in the postnatal period. The presented study has demonstrated that the metabolic syndrome deteriorates the course of pregnancy. This condition is an indication for complex evaluation by physicians of various specialities, strict control of the metabolic profile, and early administration of renal protectors</p></abstract><trans-abstract xml:lang="ru"><p>В статье изложены результаты проспективного когортного исследования динамики основных составляющих метаболического синдрома у женщин по мере прогрессирования беременности и их оценка в послеродовом периоде. Проведенное исследование подтвердило, что метаболический синдром усугубляет течение беременности. Это является показанием для комплексного обследования врачами разных специальностей, жесткого контроля метаболического профиля и раннего назначения нефропротекторов</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метаболический синдром</kwd><kwd>сахарный диабет</kwd><kwd>гестационный пиелонефрит</kwd><kwd>беременность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolic syndrome</kwd><kwd>diabetes mellitus</kwd><kwd>gestational pyelonephritis</kwd><kwd>pregnancy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кутырина И.М. Методы исследования функционального состояния почек. В кн.: Нефрология; под ред. Тареевой И.Е. Москва. -2000. -5. С. 90-92.</mixed-citation><mixed-citation xml:lang="en">Кутырина И.М. Методы исследования функционального состояния почек. В кн.: Нефрология; под ред. Тареевой И.Е. Москва. -2000. -5. С. 90-92.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Bellver J., Melo M.A., Bosch E. Obesity and poor reproductive outcome: the potential role of the endometrium. Fertil Steril 2007; 88: 446.</mixed-citation><mixed-citation xml:lang="en">Bellver J., Melo M.A., Bosch E. Obesity and poor reproductive outcome: the potential role of the endometrium. Fertil Steril 2007; 88: 446.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Brizzi P., Tonolo G., Esposito F. Lipoprotein metabolism during normal pregnancy. Am J Obstet Gynecol 1999; 181: 430.</mixed-citation><mixed-citation xml:lang="en">Brizzi P., Tonolo G., Esposito F. Lipoprotein metabolism during normal pregnancy. Am J Obstet Gynecol 1999; 181: 430.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Calandra C., Abell D.A., Beischer N.A. Maternal obesity in pregnancy. Obstet Gynecol 1981; 57: 8.</mixed-citation><mixed-citation xml:lang="en">Calandra C., Abell D.A., Beischer N.A. Maternal obesity in pregnancy. Obstet Gynecol 1981; 57: 8.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Chen A., Feresu S.A., Fernandez C. Maternal obesity and the risk of infant death in the United States. Epidemiology 2009; 20: 74.</mixed-citation><mixed-citation xml:lang="en">Chen A., Feresu S.A., Fernandez C. Maternal obesity and the risk of infant death in the United States. Epidemiology 2009; 20: 74.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med, 2002; 346: 393-403. 7. Dahlquist, G., Stattin, E.L., Rudberg, S. Urinary albumin excretion rate and glomerular filtration rate in the prediction of diabetic nephropathy; a long-term follow-up study of childhood onset type-1 diabetic patients. Nephrol Dial Transplant 2001; 16: 1382.</mixed-citation><mixed-citation xml:lang="en">Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med, 2002; 346: 393-403. 7. Dahlquist, G., Stattin, E.L., Rudberg, S. Urinary albumin excretion rate and glomerular filtration rate in the prediction of diabetic nephropathy; a long-term follow-up study of childhood onset type-1 diabetic patients. Nephrol Dial Transplant 2001; 16: 1382.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ehrenberg H.M., Iams J.D. Maternal Obesity, Uterine Activity, and the Risk of Spontaneous Preterm Birth. Obstet Gynecol 2009; 113: 48.</mixed-citation><mixed-citation xml:lang="en">Ehrenberg H.M., Iams J.D. Maternal Obesity, Uterine Activity, and the Risk of Spontaneous Preterm Birth. Obstet Gynecol 2009; 113: 48.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Jackson A.A. Nutrients, growth, and the development of programmed metabolic function. Adv Exp Med Biol 2000; 478: 41.</mixed-citation><mixed-citation xml:lang="en">Jackson A.A. Nutrients, growth, and the development of programmed metabolic function. Adv Exp Med Biol 2000; 478: 41.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">K/DOQI Clinical Practice Guidelines and Clinical Practice recommendations for diabetes and chronic kidney disease. Am J Kidney Dis 2007; 49(Suppl 2): S17.</mixed-citation><mixed-citation xml:lang="en">K/DOQI Clinical Practice Guidelines and Clinical Practice recommendations for diabetes and chronic kidney disease. Am J Kidney Dis 2007; 49(Suppl 2): S17.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">K-DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Kidney Disease Outcome Quality Initiative. Am J Kidney Dis. 2002; 39: 1-266 9. Mattix, H.J., Hsu Cy, C., Shaykevich, S., Curhan, G. Use of the albumin/creatinine ratio to detect microalbuminuria: Implications of sex and race. J Am Soc Nephrol 2002; 13: 1034.</mixed-citation><mixed-citation xml:lang="en">K-DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification and stratification. Kidney Disease Outcome Quality Initiative. Am J Kidney Dis. 2002; 39: 1-266 9. Mattix, H.J., Hsu Cy, C., Shaykevich, S., Curhan, G. Use of the albumin/creatinine ratio to detect microalbuminuria: Implications of sex and race. J Am Soc Nephrol 2002; 13: 1034.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Mann J.F., Gerstein H.C., Pogue J. et al. Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: The HOPE randomized trail. Ann Int Med 2001; 134: 629-636</mixed-citation><mixed-citation xml:lang="en">Mann J.F., Gerstein H.C., Pogue J. et al. Renal insufficiency as a predictor of cardiovascular outcomes and the impact of ramipril: The HOPE randomized trail. Ann Int Med 2001; 134: 629-636</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Perkins, B.A., Ficociello, L.H., Ostrander, B.E., et al. Microalbuminuria and the risk for early progressive renal function decline in type 1 diabetes. J Am Soc Nephrol 2007; 18: 1353.</mixed-citation><mixed-citation xml:lang="en">Perkins, B.A., Ficociello, L.H., Ostrander, B.E., et al. Microalbuminuria and the risk for early progressive renal function decline in type 1 diabetes. J Am Soc Nephrol 2007; 18: 1353.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Porrini E., Bayaes B. et al. Hyperinsulinemia and Hyperfiltration in Renal Transplantation. 2009; 87; 2: 274-279.</mixed-citation><mixed-citation xml:lang="en">Porrini E., Bayaes B. et al. Hyperinsulinemia and Hyperfiltration in Renal Transplantation. 2009; 87; 2: 274-279.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Tomaszewski M., Charchar F.J., Maric C., McClure J., Crawford L., Grzeszczak W., Sattar N. Glomerular hyperfiltration: A new marker of metabolic risk. Kidney International 2007; 71: 816-821. 14. Weiss, J.L., Malone, F.D., Emig, D., et al. FASTER research Consortium. Obesity, obstetric complications and Cesarean delivery rate -a population -based screening study. Am J Obstet Gynecol 2004; 190: 1091.</mixed-citation><mixed-citation xml:lang="en">Tomaszewski M., Charchar F.J., Maric C., McClure J., Crawford L., Grzeszczak W., Sattar N. Glomerular hyperfiltration: A new marker of metabolic risk. Kidney International 2007; 71: 816-821. 14. Weiss, J.L., Malone, F.D., Emig, D., et al. FASTER research Consortium. Obesity, obstetric complications and Cesarean delivery rate -a population -based screening study. Am J Obstet Gynecol 2004; 190: 1091.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Weiner D.E., Tighiouart H., Amin M.G., et al. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol. 2004; 15: 1307-1315</mixed-citation><mixed-citation xml:lang="en">Weiner D.E., Tighiouart H., Amin M.G., et al. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol. 2004; 15: 1307-1315</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
