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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347/ob.gyn.rep.2026.690</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-2690</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group></article-categories><title-group><article-title>Maternal tachycardia in pregnancy: a masked presentation of hyperthyroidism?</article-title><trans-title-group xml:lang="ru"><trans-title>Материнская тахикардия во время беременности: замаскированное проявление гипертиреоза?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-9775-556X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эвердин</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Everdien</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Эвердиен Альсе</p><p>KM.21 ул. Bandung Sumedang Raya, Бандунг, Западная Ява 45363</p></bio><bio xml:lang="en"><p>Alce Everdien, MD </p><p>KM.21 Bandung Sumedang Raya Str., Bandung, West Jawa 45363</p></bio><email xlink:type="simple">alce23001@mail.unpad.ac.id</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Азиз</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aziz</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Азиз Мухаммад Аламсия</p><p>KM.21 ул. Bandung Sumedang Raya, Бандунг, Западная Ява 45363</p></bio><bio xml:lang="en"><p>Muhammad Alamsyah Aziz, MD </p><p>KM.21 Bandung Sumedang Raya Str., Bandung, West Jawa 45363</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курниади</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kurniadi</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курниади Анди</p><p>KM.21 ул. Bandung Sumedang Raya, Бандунг, Западная Ява 45363</p></bio><bio xml:lang="en"><p>Andi Kurniadi, MD </p><p>KM.21 Bandung Sumedang Raya Str., Bandung, West Jawa 45363</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ниса</surname><given-names>А. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Nisa</surname><given-names>A. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ниса Айсия Шофиатун</p><p>KM.21 ул. Bandung Sumedang Raya, Бандунг, Западная Ява 45363</p></bio><bio xml:lang="en"><p>Aisyah Shofiatun Nisa, MD </p><p>KM.21 Bandung Sumedang Raya Str., Bandung, West Jawa 45363</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-8289-6617</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Субхан</surname><given-names>Д. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Subhan</surname><given-names>D. H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Субхан Даданг Хавари</p><p>Kav NO.13 ул. Letjen Suprapto, Джакарта 10510</p></bio><bio xml:lang="en"><p>Dadang Hawari Subhan, MD</p><p>Kav NO.13 Letjen Suprapto Str., Jakarta 10510</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Больница общего профиля имени доктора Хасана Садыкина, Университет Паджаджаран</institution><country>Индонезия</country></aff><aff xml:lang="en"><institution>Hasan Sadikin General Hospital, Padjajaran University</institution><country>Indonesia</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Университет YARSI</institution><country>Индонезия</country></aff><aff xml:lang="en"><institution>YARSI University</institution><country>Indonesia</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>10</day><month>05</month><year>2026</year></pub-date><volume>20</volume><issue>2</issue><fpage>380</fpage><lpage>386</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Everdien A., Aziz M.A., Kurniadi A., Nisa A.S., Subhan D.H., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Эвердин А., Азиз М.А., Курниади А., Ниса А.Ш., Субхан Д.Х.</copyright-holder><copyright-holder xml:lang="en">Everdien A., Aziz M.A., Kurniadi A., Nisa A.S., Subhan D.H.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/2690">https://www.gynecology.su/jour/article/view/2690</self-uri><abstract><sec><title>Introduction</title><p>Introduction. Hyperthyroidism occurs in 35–50 per 100,000 women aged 20–29 years annually. Pregnancy outcomes in hyperthyroid mothers depend heavily on metabolic control. This case report discusses a pregnant patient with Graves' disease who presented without the typical symptoms of hyperthyroidism or thyrotoxicosis.</p></sec><sec><title>Case report</title><p>Case report. A 31-year-old multiparous woman (gravida 3, para 2) at 38 weeks of gestation was admitted to a tertiary care center in labor. She had previously visited the emergency room due to severe diarrhea, dehydration, and hyperthyroidism. The patient received regular antenatal care at an endocrine clinic, where she was treated with propylthiouracil and propranolol until her seventh month of pregnancy. Subsequent evaluations revealed normalized thyroxine (T4) and thyroid-stimulating hormone (TSH) levels; thus, the treatment was concluded. The patient underwent an uncomplicated vaginal delivery and was safely discharged.</p></sec><sec><title>Discussion</title><p>Discussion. The patient had no prior history of thyroid disorders. Her initial symptoms emerged at two months of gestation, presenting as vomiting, dehydration, tachycardia, and weight loss. While an initial diagnosis of dehydration seemed to explain the tachycardia, laboratory tests revealed low TSH and increased free T4 (fT4) levels, confirming hyperthyroidism despite the absence of classic physical signs. Implementing maternal thyroid disorder screening to prevent such complications align with similar initiatives in Indonesia, such as the Congenital Hypothyroidism Screening program. However, expert guidelines from the American Thyroid Association and the Endocrine Society do not currently recommend universal thyroid screening in the absence of specific risk factors.</p></sec><sec><title>Conclusion</title><p>Conclusion. Optimal pregnancy outcomes in hyperthyroid patients require early diagnosis and adequate treatment. Tachycardia presenting during early pregnancy should be investigated for underlying causes other than dehydration. Although universal thyroid screening in early pregnancy is not recommended without risk factors, strong clinical suspicion remains a clear indication for further laboratory examination.</p></sec></abstract><trans-abstract xml:lang="ru"><sec><title>Введение</title><p>Введение. Гипертиреоз встречается с частотой 35–50 случаев на 100 тыс. женщин в год у женщин в возрасте 20–29 лет. У матерей с гипертиреозом исходы беременности зависят от контроля метаболизма. В данном случае рассматривается пациентка с болезнью Грейвса (Базедова болезнь) без специфических жалоб на гипертиреоз или тиреотоксикоз.</p></sec><sec><title>Клинический случай</title><p>Клинический случай. Беременная, 31 год, с двумя предыдущими беременностями и двумя родами в анамнезе, срок гестации 38 недель, была госпитализирована в родильное отделение с анамнезом обращения в отделение неотложной помощи в связи с тяжелой диареей, обезвоживанием и гипертиреозом. Пациентка регулярно наблюдалась в эндокринологической клинике и получала пропилтиоурацил и пропранолол до 7 месяцев беременности. Повторное обследование показало нормальные уровни тироксина (Т4) и тиреотропного гормона (ТТГ), поэтому лечение было завершено. Роды прошли через естественные родовые пути без осложнений, пациентка была выписана.</p></sec><sec><title>Обсуждение</title><p>Обсуждение. Пациентка – многорожавшая мать без заболеваний щитовидной железы в анамнезе. Первые жалобы возникли на втором месяце беременности и сопровождались рвотой, обезвоживанием, тахикардией и потерей массы тела. Первоначальный диагноз обезвоживания объяснял тахикардию, но лабораторные исследования выявили низкий уровень ТТГ и повышенный уровень свободного Т4 (свT4), что соответствует гипертиреозу без типичных клинических симптомов. Скрининг заболеваний щитовидной железы для профилактики этого заболевания осуществляется в соответствии с аналогичными программами, проводимыми в Индонезии, такими как скрининг врожденного гипотиреоза. Однако экспертные группы, такие как Американская ассоциация щитовидной железы и Общество эндокринологии, не рекомендуют проводить всеобщий скрининг заболеваний щитовидной железы при отсутствии факторов риска.</p></sec><sec><title>Заключение</title><p>Заключение. Оптимальные результаты достигаются при ранней диагностике и адекватном лечении. При тахикардии, возникшей на ранних сроках беременности, пациентка должна быть обследована для выявления других причин развития тахикардии, помимо обезвоживания. В настоящее время универсальный скрининг функции щитовидной железы на ранних сроках беременности не рекомендуется при отсутствии факторов риска, однако клиническое подозрение является показанием к дополнительному обследованию.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Грейвса</kwd><kwd>гипертиреоз</kwd><kwd>беременность</kwd><kwd>скрининг</kwd><kwd>тахикардия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Graves’ disease</kwd><kwd>hyperthyroidism</kwd><kwd>pregnancy</kwd><kwd>screening</kwd><kwd>tachycardia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lee S.Y., Pearce E.N. Assessment and treatment of thyroid disorders in pregnancy and the postpartum period. Nat Rev Endocrinol. 2022;18(3):158–71. https://doi.org/10.1038/s41574-021-00604-z.</mixed-citation><mixed-citation xml:lang="en">Lee S.Y., Pearce E.N. 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