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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-263</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GYNECOLOGY</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ</subject></subj-group></article-categories><title-group><article-title>PREGNANCY AND LABOR COURSE IN OBESE PATIENTS</article-title><trans-title-group xml:lang="ru"><trans-title>ТЕЧЕНИЕ БЕРЕМЕННОСТИ И РОДОВ У ПАЦИЕНТОК С ОЖИРЕНИЕМ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>И. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>I. O.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Боровкова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Borovkova</surname><given-names>E. I.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Байрамова</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Bairamova</surname><given-names>M. Yu.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский Государственный Медицинский Университет им. И.М. Сеченова, Москва</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I.M. Sechenov Moscow State Medical University (MSMU), Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>01</day><month>09</month><year>2016</year></pub-date><volume>5</volume><issue>1</issue><fpage>22</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Makarov I.O., Borovkova E.I., Bairamova M.Y., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Макаров И.О., Боровкова Е.И., Байрамова М.Ю.</copyright-holder><copyright-holder xml:lang="en">Makarov I.O., Borovkova E.I., Bairamova M.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/263">https://www.gynecology.su/jour/article/view/263</self-uri><abstract><p>A prospective, cohort study of the pregnancy and labor course in obese patients was carried out during the 2009 - 2011 period. Depending on the extent of obesity, all pregnant females were divided into three subgroups. The first subgroup comprised patients with grade I obesity (BMI - 30-34.9, n = 60), second group included patients with grade 2 obesity (BMI - 35-39.9, n = 28), and the third group included patients with grade 3 obesity (BMI - 40 and over, n = 12). All patients received complex clinical and laboratory examination. It was found that regardless of obesity grade, in the 3rd trimester every other patient develops gestosis, and every third patient develops threat of preterm labor. Females with grade 3 obesity are at a higher risk of development of not only complications of pregnancy, but also of unfavorable perinatal outcomes at that. These results and results of laboratory examinations confirm that obesity is the unfavorable background for pregnancy progression.</p></abstract><trans-abstract xml:lang="ru"><p>Проспективное когортное исследование течения беременности и родов у пациенток с ожирением проводилось в период с 2009 по 2011 год. В зависимости от степени ожирения все беременные были подразделены на три подгруппы. Первую подгруппу составили пациентки с 1 степенью ожирения (ИМТ 30-34,9, n=60), вторую - со 2 степенью ожирения (ИМТ 35-39,9, n=28), третью подгруппу - с ожирением 3 степени (ИМТ 40 и более, n=12). Всем пациенткам было проведено комплексное клинико-лабораторное обследование. Было выявлено, что вне зависимости от выраженности ожирения в III триместре у каждой второй пациентки развивается гестоз, у каждой 3-й - угроза преждевременных родов. При этом женщины с ожирением 3 степени имеют больший риск развития не только осложнений беременности, но и неблагоприятных перинатальных исходов. Данные результаты и результаты лабораторных исследований подтверждают, что ожирение является неблагоприятным фоном для развития беременности</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>роды</kwd><kwd>ожирение</kwd><kwd>метаболический синдром</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>labor</kwd><kwd>obesity</kwd><kwd>metabolic syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bellver J, Melo, MA, Bosch, E. Obesity and poor reproductive outcome: the potential role of the endometrium. Fertil Steril 2007; 88:446.</mixed-citation><mixed-citation xml:lang="en">Bellver J, Melo, MA, Bosch, E. Obesity and poor reproductive outcome: the potential role of the endometrium. 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