<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347/ob.gyn.rep.2025.614</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-2549</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group></article-categories><title-group><article-title>Treatment of secondary vaginal atresia with the Martius-Symmonds flap</article-title><trans-title-group xml:lang="ru"><trans-title>Лечение вторичной атрезии влагалища с помощью лоскута Martius-Symmonds</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2645-1662</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ящук</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Yashchuk</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ящук Альфия Галимовна - д.м.н., проф.</p><p>450008 Уфа, ул. Ленина, д. 3</p><p>Scopus Author ID 57199647955</p></bio><bio xml:lang="en"><p>Alfiya G. Yashchuk - MD, Dr Sci Med, Prof.</p><p>3 Lenin Str., Ufa 450008</p><p>Scopus Author ID 57199647955</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0855-7754</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Губанова</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Gubanova</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Губанова Елена Геннадьевна.</p><p>450008 Уфа, ул. Ленина, д. 3</p></bio><bio xml:lang="en"><p>Elena G. Gubanova - MD.</p><p>3 Lenin Str., Ufa 450008</p></bio><email xlink:type="simple">ekaz4ntseva@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5520-5845</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мусин</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Musin</surname><given-names>I. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мусин Ильнур Ирекович - д.м.н.</p><p>450008 Уфа, ул. Ленина, д. 3</p><p>Scopus Author ID 57199649436</p></bio><bio xml:lang="en"><p>Ilnur I. Musin - MD, Dr Sci Med.</p><p>3 Lenin Str., Ufa 450008</p><p>Scopus Author ID 57199649436</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1641-9952</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Батталова</surname><given-names>Г. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Battalova</surname><given-names>G. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Батталова Гюзель Юрьевна - д.м.н., проф.</p><p>450008 Уфа, ул. Ленина, д. 3</p><p>Scopus Author ID 57724688300</p></bio><bio xml:lang="en"><p>Guzel Yu. Battalova - MD, Dr Sci Med, Prof.</p><p>3 Lenin Str., Ufa 450008</p><p>Scopus Author ID 57724688300</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4657-6625</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Урманцев</surname><given-names>М. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Urmantsev</surname><given-names>M. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Урманцев Марат Фаязович - к.м.н.</p><p>450008 Уфа, ул. Ленина, д. 3</p><p>Scopus Author ID 56149491500</p></bio><bio xml:lang="en"><p>Marat F. Urmantsev - MD, PhD.</p><p>3 Lenin Str., Ufa 450008</p><p>Scopus Author ID 56149491500</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Башкирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University, Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>10</day><month>09</month><year>2025</year></pub-date><volume>19</volume><issue>4</issue><fpage>608</fpage><lpage>613</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Yashchuk A.G., Gubanova E.G., Musin I.I., Battalova G.Y., Urmantsev M.F., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Ящук А.Г., Губанова Е.Г., Мусин И.И., Батталова Г.Ю., Урманцев М.Ф.</copyright-holder><copyright-holder xml:lang="en">Yashchuk A.G., Gubanova E.G., Musin I.I., Battalova G.Y., Urmantsev M.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/2549">https://www.gynecology.su/jour/article/view/2549</self-uri><abstract><p>Secondary vagina atresia is a quite rare pathology, and due to its low incidence, the lack of standardized recommendations for the management of this group of patients, as well as the insufficient number of relevant randomized trials, the analysis of individual clinical cases is of special relevance. An analysis of the clinical case of a female patient with acquired vaginal atresia underwent surgical treatment – vaginal reconstruction with a Martius-Symmonds flap is presented. In dynamics, after the surgical intervention, good healing and autograft adaptation were noted, without necrosis and ulceration in the area of Martius-Symmonds flap transplantation, with neovagina sized up to 6.5 cm long and 3 to 4 cm wide in different localization. Due to the lack of standardized recommendations for management of patients with acquired vaginal atresia, it is necessary to continue examining and discussing such cases in clinical practice.</p></abstract><trans-abstract xml:lang="ru"><p>Вторичная атрезия влагалища является достаточно редкой патологией. По причине небольшой частоты распространения представленной патологии, отсутствия стандартизированных рекомендаций по ведению данной группы пациенток, а также недостаточного количества рандомизированных исследований по данной проблеме особую актуальность приобретает разбор отдельных клинических случаев. Приводится разбор клинического случая пациентки с приобретенной атрезией влагалища, которой проведено оперативное лечение – реконструкция влагалища лоскутом Martius-Symmonds. В динамике после хирургического вмешательства отмечена хорошая заживляемость и адаптация аутотрансплантанта, некроза и изъязвления в области пересадки лоскута Martius-Symmonds не отмечалось, созданное неовлагалище имеет длину до 6,5 см, ширину от 3 до 4 см в различной локализации. Ввиду отсутствия стандартизированных рекомендаций ведения пациенток с приобретенной атрезией влагалища необходимо продолжать изучение и обсуждение подобных случаев в клинической практике.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>вторичная атрезия влагалища</kwd><kwd>лоскут Martius-Symmonds</kwd><kwd>неовагина</kwd></kwd-group><kwd-group xml:lang="en"><kwd>secondary vaginal atresia</kwd><kwd>Martius-Symmonds flap</kwd><kwd>neovagina</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Уварова Е.В., Тарусин Д.И. Пособие по обследованию состояния репродуктивной системы детей и подростков. М.: Триада-Х, 2009. 232 с.</mixed-citation><mixed-citation xml:lang="en">Uvarova E.V., Tarusin D.I. Manual for examination of the reproductive system of children and adolescents. [Posobie po obsledovaniyu sostoyaniya reproduktivnoj sistemy detej i podrostkov]. Moscow: Triada-X, 2009. 232 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Lin W.C, Chang C.Y.Y., Shen Y.Y., Tsai H.D. Use of autologous buccal mucosa for vaginoplasty: a study of eight cases. Hum Reprod. 2003;18(3):604–07. https://doi.org/10.1093/humrep/deg095.</mixed-citation><mixed-citation xml:lang="en">Lin W.C, Chang C.Y.Y., Shen Y.Y., Tsai H.D. Use of autologous buccal mucosa for vaginoplasty: a study of eight cases. Hum Reprod. 2003;18(3):604–07. https://doi.org/10.1093/humrep/deg095.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Frank R.T. The formation of an artificial vagina without operation. Am J Obstet Gynecol. 1938;35:1053–5.</mixed-citation><mixed-citation xml:lang="en">Frank R.T. The formation of an artificial vagina without operation. Am J Obstet Gynecol. 1938;35:1053–5.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Nakhal R.S., Creighton S.M. Management of vaginal agenesis. J Pediatr Adolesc Gynecol. 2012;25(6):352–7. https://doi.org/10.1016/j.jpag.2011.06.003.</mixed-citation><mixed-citation xml:lang="en">Nakhal R.S., Creighton S.M. Management of vaginal agenesis. J Pediatr Adolesc Gynecol. 2012;25(6):352–7. https://doi.org/10.1016/j.jpag.2011.06.003.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">McQuillan S.K., Grover S.R. Dilation and surgical management in vaginal agenesis: a systematic review. Int Urogynecol J. 2014;25(3):299–311. https://doi.org/10.1007/s00192-013-2221-9.</mixed-citation><mixed-citation xml:lang="en">McQuillan S.K., Grover S.R. Dilation and surgical management in vaginal agenesis: a systematic review. Int Urogynecol J. 2014;25(3):299–311. https://doi.org/10.1007/s00192-013-2221-9.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Graves W.P. Method of reconstruction of an artificial vagina. Surg Clin North Am. 1921;1:611–4.</mixed-citation><mixed-citation xml:lang="en">Graves W.P. Method of reconstruction of an artificial vagina. Surg Clin North Am. 1921;1:611–4.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Brady L. Methods of constructing a vagina. Ann Surg. 1945;121(4):518–29. https://doi.org/10.1097/00000658-194504000-00011.</mixed-citation><mixed-citation xml:lang="en">Brady L. Methods of constructing a vagina. Ann Surg. 1945;121(4):518–29. https://doi.org/10.1097/00000658-194504000-00011.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Williams E.A. Congenital absence of the vagina: a simple operation for its relief. J Obstet Gynaecol Br Commonw. 1964;71:511–2. https://doi.org/10.1111/j.1471-0528.1964.tb04315.x.</mixed-citation><mixed-citation xml:lang="en">Williams E.A. Congenital absence of the vagina: a simple operation for its relief. J Obstet Gynaecol Br Commonw. 1964;71:511–2. https://doi.org/10.1111/j.1471-0528.1964.tb04315.x.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Hwang W.Y., Chang T.S., Sun P., Chung T.H. Vaginal reconstruction using labia minora flaps in congenital total absence. Ann Plast Surg. 1985;15(6):534–7. https://doi.org/10.1097/00000637-198512000-00013.</mixed-citation><mixed-citation xml:lang="en">Hwang W.Y., Chang T.S., Sun P., Chung T.H. Vaginal reconstruction using labia minora flaps in congenital total absence. Ann Plast Surg. 1985;15(6):534–7. https://doi.org/10.1097/00000637-198512000-00013.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации – Рак шейки матки. М.: Министерство здравоохранения Российской Федерации, 2020. 66 с. Режим доступа: https://old.oncology-association.ru/files/clinical-guidelines-2020/rak_shejki_matki.pdf. [Дата обращения: 15.12.2024].</mixed-citation><mixed-citation xml:lang="en">Clinical guidelines – Cervical cancer. [Klinicheskie rekomendacii – Rak shejki matki]. Moscow: Ministerstvo zdravoohraneniya Rossijskoj Federacii, 2020. 66 p. (In Russ.). Available at: https://old.oncology-association.ru/files/clinical-guidelines-2020/rak_shejki_matki.pdf. [Accessed: 15.12.2024].</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rothenberger R., Feroz R., Hogarth N. et al. Ideal incision and dissection for Martius flap: a cadaver-based study on nerve and vascular density. Am J Obstet Gynecol. 2024;230(4S):S1225–S1226. https://www.ajog.org/article/S0002-9378(24)00201-1/fulltext.</mixed-citation><mixed-citation xml:lang="en">Rothenberger R., Feroz R., Hogarth N. et al. Ideal incision and dissection for Martius flap: a cadaver-based study on nerve and vascular density. Am J Obstet Gynecol. 2024;230(4S):S1225–S1226. https://www.ajog.org/article/S0002-9378(24)00201-1/fulltext.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Beksac M.S., Salman M.C., Dogan N.U. A new technique for surgical treatment of vaginal agenesis using combined abdominal-perineal approach. Case Rep Med. 2011;2011:120175. https://doi.org/10.1155/2011/120175.</mixed-citation><mixed-citation xml:lang="en">Beksac M.S., Salman M.C., Dogan N.U. A new technique for surgical treatment of vaginal agenesis using combined abdominal-perineal approach. Case Rep Med. 2011;2011:120175. https://doi.org/10.1155/2011/120175.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ugur M.G., Balat O., Ozturk E. et al. Pitfalls in diagnosis and management of distal vaginal agenesis: 10-year experience at a single centre. Eur J Obstet Gynecol Reprod Biol. 2012;163(1):85–90. https://doi.org/10.1016/j.ejogrb.2012.03.024.</mixed-citation><mixed-citation xml:lang="en">Ugur M.G., Balat O., Ozturk E. et al. Pitfalls in diagnosis and management of distal vaginal agenesis: 10-year experience at a single centre. Eur J Obstet Gynecol Reprod Biol. 2012;163(1):85–90. https://doi.org/10.1016/j.ejogrb.2012.03.024.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Michala L., Cutner A., Creighton S.M. Surgical approaches to treating vaginal agenesis. BJOG. 2007;114(12):1455–9. https://doi.org/10.1111/j.1471-0528.2007.01547.x.</mixed-citation><mixed-citation xml:lang="en">Michala L., Cutner A., Creighton S.M. Surgical approaches to treating vaginal agenesis. BJOG. 2007;114(12):1455–9. https://doi.org/10.1111/j.1471-0528.2007.01547.x.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Callahan T., Caughey A.B. Blueprints obstetrics and gynecology. Philadelphia: Wolters Kluwer Health/Lippincott William and Wilkins, 2009. 401 p.</mixed-citation><mixed-citation xml:lang="en">Callahan T., Caughey A.B. Blueprints obstetrics and gynecology. Philadelphia: Wolters Kluwer Health/Lippincott William and Wilkins, 2009. 401 p.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kölle A., Taran F.-A., Rall K. et al. Neovagina creation methods and their potential impact on subsequent uterus transplantation: a review. BJOG. 2019;126(11):1328–35. https://doi.org/10.1111/1471-0528.15888.</mixed-citation><mixed-citation xml:lang="en">Kölle A., Taran F.-A., Rall K. et al. Neovagina creation methods and their potential impact on subsequent uterus transplantation: a review. BJOG. 2019;126(11):1328–35. https://doi.org/10.1111/1471-0528.15888.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Rathod S., Samal S.K. Secondary vaginal atresia treated with vaginoplasty using amnion graft: a case report. J Clin Diagn Res. 2014;8(11):OD05– OD06. https://doi.org/10.7860/JCDR/2014/10674.5207.</mixed-citation><mixed-citation xml:lang="en">Rathod S., Samal S.K. Secondary vaginal atresia treated with vaginoplasty using amnion graft: a case report. J Clin Diagn Res. 2014;8(11):OD05–OD06. https://doi.org/10.7860/JCDR/2014/10674.5207.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
