akusherstvoObstetrics, Gynecology and ReproductionАкушерство, Гинекология и Репродукция2313-73472500-3194IRBIS LLC10.17749/2313-7347/ob.gyn.rep.2025.628akusherstvo-2421Research ArticleREVIEW ARTICLESНАУЧНЫЕ ОБЗОРЫMinimally invasive and robot-assisted interventions in the treatment of gynecological malignant tumors: opportunities for preserving reproductive functionМинимально инвазивные и робот-ассистированные вмешательства в лечении гинекологических злокачественных опухолей: возможности сохранения репродуктивной функцииhttps://orcid.org/0009-0004-2111-467XХамадьяноваА. У.KhamadyanovaA. U.

Хамадьянова Аида Ульфатовна - к.м.н.

450008 Уфа, ул. Ленина, д. 3

Aida U. Khamadyanova - MD, PhD.

3 Lenin Str., Ufa 450008

aida.khamadyanova@mail.ruhttps://orcid.org/0009-0004-4565-8022ГаевТ. Т.GaevT. T.

Гаев Тамерлан Толикович.

362019 Республика Северная Осетия–Алания, Владикавказ, ул. Пушкинская, д. 40

Tamerlan T. Gaev.

40 Pushkinskaya Str., Vladikavkaz, Republic of North Ossetia-Alania 362019

https://orcid.org/0009-0005-0359-0362ГацоевД. О.GatsoevD. O.

Гацоев Дзамболат Олегович.

362019 Республика Северная Осетия–Алания, Владикавказ, ул. Пушкинская, д. 40

Dzambolat O. Gatsoev.

40 Pushkinskaya Str., Vladikavkaz, Republic of North Ossetia-Alania 362019

https://orcid.org/0009-0000-0075-1603АндреевВ. В.AndreevV. V.

Андреев Вадим Валерьевич.

603000 Нижний Новгород, площадь Минина и Пожарского, д. 10/1

Vadim V. Andreev.

10/1 Minin and Pozharsky Square, Nizhny Novgorod 603000

https://orcid.org/0009-0000-4069-4949ПажитноваА. С.PazhitnovaA. S.

Пажитнова Ангелина Сергеевна.

117513 Москва, ул. Островитянова, д. 1

Angelina S. Pazhitnova.

1 Ostrovityanova Str., Moscow 117513

https://orcid.org/0009-0005-5106-8122ТихоноваЭ. О.TikhonovaE. O.

Тихонова Эльвира Олеговна.

350063 Краснодар, ул. Митрофана Седина, д. 4

Elvira O. Tikhonova.

4 Mitrofana Sedina Str., Krasnodar 350063

https://orcid.org/0009-0002-6266-8260КимВ. Г.KimV. G.

Ким Владимир Георгиевич.

630091 Новосибирск, ул. Красный проспект, д. 52

Vladimir G. Kim.

52 Krasny Prospekt, Novosibirsk 630091

https://orcid.org/0009-0005-5398-3738ТалалаеваД. А.TalalaevaD. A.

Талалаева Дарья Андреевна.

450008 Уфа, ул. Ленина, д. 3

Daria A. Talalaeva.

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0003-6298-8763АгаповаВ. Е.AgapovaV. V.

Агапова Виктория Евгеньевна.

117513 Москва, ул. Островитянова, д. 1

Victoriya E. Agapova.

1 Ostrovityanova Str., Moscow 117513

https://orcid.org/0009-0002-4215-385XБотинаР. С.BotinaR. S.

Ботина Регина Сергеевна.

420008 Казань, ул. Кремлевская, д. 18

Regina S. Botina.

18 Kremlevskaya Str., Kazan 420008

https://orcid.org/0009-0004-5135-0593ЯковлеваА. К.YakovlevaA. K.

Яковлева Арина Константиновна.

420008 Казань, ул. Кремлевская, д. 18

Arina K. Yakovleva.

18 Kremlevskaya Str., Kazan 420008

https://orcid.org/0009-0006-4819-5638ВасильеваС. Д.VasilievaS. D.

Васильева София Дмитриевна.

450008 Уфа, ул. Ленина, д. 3

Sofiya D. Vasilieva.

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0008-0804-3036БакулинД. Ю.BakulinD. Yu.

Бакулин Дмитрий Юрьевич.

117513 Москва, ул. Островитянова, д. 1

Dmitrii Yu. Bakulin.

1 Ostrovityanova Str., Moscow 117513

ФГБОУ ВО «Башкирский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияBashkir State Medical University, Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО «Северо-Осетинская государственная медицинская академия» Министерства здравоохранения Российской ФедерацииРоссияNorth Ossetian State Medical Academy, Ministry of Health of the Russian FederationRussian FederationФГБУ ВО «Приволжский исследовательский медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияPrivolzhsky Research Medical University, Ministry of Health of the Russian FederationRussian FederationФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Министерства здравоохранения Российской ФедерацииРоссияPirogov Russian National Research Medical University, Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО «Кубанский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияKuban State Medical University, Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияNovosibirsk State Medical University, Ministry of Health of the Russian FederationRussian FederationФГАОУ ВО «Казанский (Приволжский) федеральный университет»РоссияKazan (Privolzhsky) Federal UniversityRussian Federation202510092025194545560Copyright © Khamadyanova A.U., Gaev T.T., Gatsoev D.O., Andreev V.V., Pazhitnova A.S., Tikhonova E.O., Kim V.G., Talalaeva D.A., Agapova V.V., Botina R.S., Yakovleva A.K., Vasilieva S.D., Bakulin D.Y., 20252025Хамадьянова А.У., Гаев Т.Т., Гацоев Д.О., Андреев В.В., Пажитнова А.С., Тихонова Э.О., Ким В.Г., Талалаева Д.А., Агапова В.Е., Ботина Р.С., Яковлева А.К., Васильева С.Д., Бакулин Д.Ю.Khamadyanova A.U., Gaev T.T., Gatsoev D.O., Andreev V.V., Pazhitnova A.S., Tikhonova E.O., Kim V.G., Talalaeva D.A., Agapova V.V., Botina R.S., Yakovleva A.K., Vasilieva S.D., Bakulin D.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gynecology.su/jour/article/view/2421Aim

Aim: to systematize and analyze current data on the use of minimally invasive and robot-assisted interventions in the treatment of gynecologic malignant tumors in reproductive age women who wish to preserve fertility.

Materials and Methods

Materials and Methods. The search was conducted in the PubMed/MEDLINE, Scopus, Web of Science, and eLibrary databases among the primary sources published from 01.01.2000 tо 28.02.2025. There were retrieved keywords and MeSH (Medical Subject Headings) terms including: “robotic surgery”, “robot-assisted surgery”, “fertility preservation”, “gynecologic cancer”, “cervical cancer”, “endometrial cancer”, “ovarian cancer”, “reproductive age”, “minimally invasive surgery”, “uterine transplantation”, as well as the corresponding Russian terms. Original studies focusing on oncologic and reproductive outcomes in women under the age of 45 were included in the analysis. The methodology followed the PRISMA guidelines. The final analysis included 53 publications.

Results

Results. The data evidence about the effectiveness and oncologic safety of fertility-preserving approaches in early-stage cervical, endometrial, and ovarian cancer. Robot-assisted interventions vs. conventional techniques demonstrated comparable or superior outcomes in fertility preservation with fewer complications and faster recovery. Additional topics addressed include ovarian transposition, uterine transplantation, and alternative fertility preservation strategies.

Conclusion

Conclusion. Robot-assisted surgery extends the potential for fertility-sparing treatment of gynecologic malignant tumors in reproductive age women. Such interventions should be performed in specialized centers by multidisciplinary teams. Further research is needed to standardize treatment protocols and evaluate long-term oncologic and reproductive outcomes.

Цель

Цель: систематизировать и проанализировать современные данные по применению минимально инвазивных и робот-ассистированных вмешательств в лечении гинекологических злокачественных опухолей у женщин репродуктивного возраста, заинтересованных в сохранении фертильности.

Материалы и методы

Материалы и методы. Поиск проводился в базах данных PubMed/MEDLINE, Scopus, Web of Science и eLibrary среди первоисточников, опубликованных в период с 01.01.2000 по 28.02.2025. Использовались ключевые слова и термины MeSH (англ. Medical Subject Headings; медицинские предметные заголовки) на русском и английском языках: «роботизированная хирургия», ««робот-ассистированная хирургия», «сохранение фертильности», «гинекологический рак», «рак шейки матки», «рак эндометрия», «рак яичников», «репродуктивный возраст», «малоинвазивная хирургия», «трансплантация матки», «robotic surgery», «robot-assisted surgery», «fertility preservation», «gynecologic cancer», «cervical cancer», «endometrial cancer», «ovarian cancer», «reproductive age», «minimally invasive surgery», «uterus transplantation». В анализ включались оригинальные исследования, в которых рассматривались онкологические и репродуктивные исходы у женщин до 45 лет. Методология соответствовала рекомендациям PRISMA. В итоговый анализ было включено 53 публикации.

Результаты

Результаты. Данные свидетельствуют о высокой эффективности и онкологической безопасности органосохраняющих подходов у пациенток с ранними стадиями рака шейки матки, эндометрия и яичников. Роботизированные вмешательства продемонстрировали сопоставимые или превосходящие результаты по сравнению с традиционными методами в отношении сохранения фертильности, при этом снижая частоту осложнений и ускоряя восстановление. Представлены данные по транспозиции яичников, трансплантации матки и альтернативным методам сохранения фертильности.

Заключение

Заключение. Робот-ассистированная хирургия расширяет возможности органосохраняющего лечения гинекологических злокачественных опухолей у женщин репродуктивного возраста. Подобные вмешательства должны проводиться в условиях специализированных центров с участием мультидисциплинарной команды. Дальнейшие исследования необходимы для стандартизации подходов и оценки долгосрочных репродуктивных и онкологических исходов.

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The authors declare that there are no conflicts of interest present.