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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347/ob.gyn.rep.2025.604</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-2362</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group></article-categories><title-group><article-title>Spontaneous uterine rupture in a multiparous woman without uterus scar</article-title><trans-title-group xml:lang="ru"><trans-title>Спонтанный разрыв матки у многорожавшей женщины без рубца на матке</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2295-2793</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бодыков</surname><given-names>Г. Ж.</given-names></name><name name-style="western" xml:lang="en"><surname>Bodykov</surname><given-names>G. Zh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бодыков Гани Жандиярович, д.м.н., проф. НАН Республики Казахстан</p><p>050000 Алматы, проспект Абылай хана, д. 51/53</p></bio><bio xml:lang="en"><p>Gani Zh. Bodykov, MD, Dr Sci Med, Prof. of NAS of the Republic of Kazakhstan</p><p>51/53 Abylai khan Avenue, Almaty 050000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4792-5380</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Локшин</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lokshin</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Локшин Вячеслав Нотанович, д.м.н., проф., академик НАН Республики Казахстан</p><p>005060 Алматы, ул. Утепова, д. 32а</p></bio><bio xml:lang="en"><p>Vyacheslav N. Lokshin, MD, Dr Sci Med, Prof., Academician of NAS of the Republic of Kazakhstan</p><p>32а Utepov Str., Almaty 005060</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-8839-0028</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мухаметова</surname><given-names>Э. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Mukhametova</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мухаметова Эльмира Ериковна </p><p>050012 Алматы, ул. Толе би, д. 94</p></bio><bio xml:lang="en"><p>Elmira E. Mukhametova, MD</p><p>94 Tole bi Str., Almaty 050012</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2655-598X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бищекова</surname><given-names>Б. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bishekova</surname><given-names>B. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бищекова Балзира Нагашибаевна, к.м.н. </p><p>050012 Алматы, ул. Толе би, д. 94</p></bio><bio xml:lang="en"><p>Balzira N. Bishekova, MD, PhD</p><p>94 Tole bi Str., Almaty 050012</p></bio><email xlink:type="simple">b_balzira@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НУО «Казахстанско-Российский медицинский университет»</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>Kazakhstan-Russian Medical University, NSEI</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ТОО «Международный клинический центр репродуктологии "PERSONA"»</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>«PERSONA» International Clinic of Reproductive Health, LLP</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>НАО «Казахский национальный медицинский университет имени С.Д. Асфендиярова»</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>Asfendiyarov Kazakh National Medical University, NCJSC</institution><country>Kazakhstan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>10</day><month>05</month><year>2025</year></pub-date><volume>19</volume><issue>2</issue><fpage>299</fpage><lpage>305</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Bodykov G.Z., Lokshin V.N., Mukhametova E.E., Bishekova B.N., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Бодыков Г.Ж., Локшин В.Н., Мухаметова Э.Е., Бищекова Б.Н.</copyright-holder><copyright-holder xml:lang="en">Bodykov G.Z., Lokshin V.N., Mukhametova E.E., Bishekova B.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/2362">https://www.gynecology.su/jour/article/view/2362</self-uri><abstract><p>Spontaneous uterine rupture during pregnancy is a life-threatening complication that predominantly occurs in the third trimester. A scar resulting from a prior cesarean section represents the primary risk factor for uterine rupture. It is one of the most severe complications in obstetrics, accompanied by bleeding, severe traumatic and hemorrhagic shock, and high perinatal mortality for both the fetus and the woman. Cases of uterine rupture without commonly accepted risk factors, regardless of parity or gestational age, have been described in the literature. Here, we present a clinical case of a complete uterine rupture occurred outside a medical facility at gestational age of 25 weeks in a multiparous woman with a complicated obstetric-gynecological history, lacking uterine scar. This was accompanied by severe hemorrhagic shock, cardiac arrest, and antenatal fetal demise. High-quality specialized care resulted in a favorable outcome for the mother.</p></abstract><trans-abstract xml:lang="ru"><p>Спонтанный разрыв матки во время беременности является угрожающим для жизни осложнением, которое возникает преимущественно в III триместре, основным фактором риска разрыва матки является наличие рубца после кесарева сечения. Это одно из самых тяжелых осложнений в акушерстве, сопровождающееся кровотечением, тяжелым травматическим и геморрагическим шоком, с высокой перинатальной смертностью плода и женщины. В литературе описаны случаи разрыва матки при отсутствии общепринятых факторов риска, независимо от паритета родов и срока гестации. В данной статье описан клинический случай полного разрыва матки вне стационара в сроке беременности 25 недель у многорожавшей с отягощенным акушерско-гинекологическим анамнезом, без рубца на матке, сопровождавшийся развитием тяжелого геморрагического шока, остановкой сердечной деятельности и антенатальной гибелью плода. Высококвалифицированная специализированная помощь определила благоприятный исход для матери.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>многорожавшая</kwd><kwd>разрыв матки</kwd><kwd>кровотечение</kwd><kwd>врастание плаценты</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>multiparous</kwd><kwd>uterine rupture</kwd><kwd>bleeding</kwd><kwd>placenta percreta</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Оленев А.С., Вученович Ю.Д., Новикова В.А., Радзинский В.Е. Разрыв матки и риски near miss. Акушерство и гинекология. Новости. Мнения. Обучение. 2019;7(3):55–63. https://doi.org/10.24411/2303-9698-2019-13008. .</mixed-citation><mixed-citation xml:lang="en">Olenev A.S., Vuchenovich Yu.D., Novikova V.A., Radzinsky V.E. Uterine rupture and risk of near miss. [Razryv matki i riski near miss]. Akusherstvo i ginekologiya. Novosti. Mneniya. Obuchenie. 2019;7(3):55–63. (In Russ.). https://doi.org/10.24411/2303- 9698-2019-13008.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Шибельгут Н.М., Батина Н.А., Иванникова А.В. и др. Разрыв матки по рубцу во время беременности. Мать и Дитя в Кузбассе. 2023;(4):92–6. https://doi.org/10.24412/2686-7338-2023-4-92-96.</mixed-citation><mixed-citation xml:lang="en">Shibelgut N.M., Batina N.A., Ivannikova A.V. et al. Rupture of the uterus along the scar during pregnancy. [Razryv matki po rubcu vo vremya beremennosti]. Mat' i Ditya v Kuzbasse. 2023;(4):92–6. (In Russ.). https://doi.org/10.24412/2686-7338-2023-4-92-96</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Гусева О.И. Разрывы матки: анализ случаев. Медицинский альманах. 2018;(6):52–5. https://doi.org/10.21145/2499-9954-2018-6-52-55.</mixed-citation><mixed-citation xml:lang="en">Guseva O.I. Uterine ruptures: case analysis. [Razryvy matki: analiz sluchaev]. Medicinskij al'manah. 2018;(6):52–5. (In Russ.). https://doi.org/10.21145/2499-9954-2018-6-52-55.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Айламазян Э.К. Неотложная помощь в акушерстве: руководство для врачей. 5-е изд. М.: ГЭОТАР-Медиа, 2015. 384 с.</mixed-citation><mixed-citation xml:lang="en">Ailamazyan E.K. Emergency care in obstetrics: a guide for doctors. 5th ed. [Neotlozhnaya pomoshch' v akusherstve: rukovodstvo dlya vrachej. 5-e izd.]. Moscow: GEOTAR-Media, 2015. 384 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ko?ec V, ?ukelj M, Djakovi? I, Butorac D. Uterine rupture in third trimester of pregnancy following cornual resection dueto ectopic pregnancy. Acta Clin Croat. 2021;60(1):153–5. https://doi.org/10.20471/acc.2021.60.01.23.</mixed-citation><mixed-citation xml:lang="en">Ko?ec V, ?ukelj M, Djakovi? I, Butorac D. Uterine rupture in third trimester of pregnancy following cornual resection dueto ectopic pregnancy. Acta Clin Croat. 2021;60(1):153–5. https://doi.org/10.20471/acc.2021.60.01.23.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Liu Y., Fu N., Lv B. et al. Uterine rupture after high-intensity focused ultrasound ablation of adenomyosis: a casereport and literature review. Int J Hyperthermia. 2023;40(1):2212885. https://doi.org/10.1080/02656736.2023.2212885.</mixed-citation><mixed-citation xml:lang="en">Liu Y., Fu N., Lv B. et al. Uterine rupture after high-intensity focused ultrasound ablation of adenomyosis: a casereport and literature review. Int J Hyperthermia. 2023;40(1):2212885. https://doi.org/10.1080/02656736.2023.2212885.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Савельева Г.М., Бреслав И.Ю. Разрыв неоперированной матки во время родов (редакционная статья). Российский вестник акушера-гинеколога. 2016;16(2):4–10. https://doi.org/10.17116/rosakush20161624-10.</mixed-citation><mixed-citation xml:lang="en">Savelyeva G.M., Breslav I.Yu. Rupture of the unoperable uterus during labor: editorial. [Razryv neoperirovannoj matki vo vremya rodov]. Rossijskij vestnik akushera-ginekologa. 2016;16(2):4–10. (In Russ.). https://doi.org/10.17116/rosakush20161624-10.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Dow M., Wax J.R., Pinette M.G. et al. Third-trimester uterine rupture without previous cesarean: a case series and review of the literature. Am J Perinatol. 2009;26(10):739–44. https://doi.org/10.1055/s-0029-1223287.</mixed-citation><mixed-citation xml:lang="en">Dow M., Wax J.R., Pinette M.G. et al. Third-trimester uterine rupture without previous cesarean: a case series and review of the literature. Am J Perinatol. 2009;26(10):739–44. https://doi.org/10.1055/s-0029-1223287.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Retzke J.D., Book N.M., Stempel L.E. Spontaneous second-trimester uterine rupture in the absence of known risk factors: a case report. J Reprod Med. 2009;54(8):525–8.</mixed-citation><mixed-citation xml:lang="en">Retzke J.D., Book N.M., Stempel L.E. Spontaneous second-trimester uterine rupture in the absence of known risk factors: a case report. J Reprod Med. 2009;54(8):525–8.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Цхай В.Б., Глызина Ю.Н., Дудина А.Ю. Спонтанный разрыв матки по задней стенке при доношенной беременности у ранее нерожавшей пациентки. Акушерство и гинекология. 2013;(5):103–6.</mixed-citation><mixed-citation xml:lang="en">Tshai V.B., Glyzina Yu.N., Dudina A.Y. Spontaneous hysterorrhexis along the posterior wall during full-term pregnancy in a nulliparous patient. [Spontannyj razryv matki po zadnej stenke pri donoshennoj beremennosti u ranee nerozhavshej pacientki]. Akusherstvo i ginekologiya. 2013;(5):103–6. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hasm?ller S., Ehrhardt H., Kahlert S. et al. Peripartum bilateral uterine rupture in a patient with mixed connective tissue disease with favorable outcome for the severely asphyctic newborn after hypothermia. Arch Gynecol Obstet. 2010;281(4):617–21. https://doi.org/10.1007/s00404-009-1273-z.</mixed-citation><mixed-citation xml:lang="en">Hasm?ller S., Ehrhardt H., Kahlert S. et al. Peripartum bilateral uterine rupture in a patient with mixed connective tissue disease with favorable outcome for the severely asphyctic newborn after hypothermia. Arch Gynecol Obstet. 2010;281(4):617–21. https://doi.org/10.1007/s00404-009-1273-z.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Sakr R., Berkane N., Barranger E. et al. Unscarred uterine rupture – case report and literature review. Clin Exp Obstet Gynecol. 2007;34(3):190–2.</mixed-citation><mixed-citation xml:lang="en">Sakr R., Berkane N., Barranger E. et al. Unscarred uterine rupture – case report and literature review. Clin Exp Obstet Gynecol. 2007;34(3):190–2.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Chen F.-P. Term delivery after repair of a uterine rupture during the second trimester in a previously unscarred uterus: a case report. J Reprod Med. 2007;52(10):981–3.</mixed-citation><mixed-citation xml:lang="en">Chen F.-P. Term delivery after repair of a uterine rupture during the second trimester in a previously unscarred uterus: a case report. J Reprod Med. 2007;52(10):981–3.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Sikora-Szcze?niak D. Uterine rupture superficial externum – a case report. Ginekol Pol. 2012;83(5):380–3. (In Polish).</mixed-citation><mixed-citation xml:lang="en">Sikora-Szcze?niak D. Uterine rupture superficial externum – a case report. Ginekol Pol. 2012;83(5):380–3. (In Polish).</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Sikora W., Michalak Z., Sikora-Szcze?niak D. Partial uterine rupture – case report. Ginekol Pol. 2010;81(4):303–4. (In Polish).</mixed-citation><mixed-citation xml:lang="en">Sikora W., Michalak Z., Sikora-Szcze?niak D. Partial uterine rupture – case report. Ginekol Pol. 2010;81(4):303–4. (In Polish).</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Можейко Л.Ф., Акулич Н.С., Коршикова Р.Л. и др. Клинический случай спонтанного разрыва оперированной матки по рубцу во время беременности. Медицинские новости. 2019;(5):15–8.</mixed-citation><mixed-citation xml:lang="en">Mozheiko L.F., Akulich N.S., Korshikova R.L. et al. Clinical case of spontaneous breakdown of the operated uterine on the scone during pregnancy. [Klinicheskij sluchaj spontannogo razryva operirovannoj matki po rubcu vo vremya beremennosti]. Medicinskie novosti. 2019;(5):15–8. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Радзинский В.Е. Акушерская агрессия v.2.0. М.: Status Praesens, 2017. 603–4.</mixed-citation><mixed-citation xml:lang="en">Radzinsky V.E. Obstetric aggression v.2.0. [Akusherskaya agressiya v.2.0]. Moscow: Status Praesens, 2017. P. 603–4. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Клинический протокол диагностики и лечения. Антенатальный уход. Одобрен Объединенной комиссией по качеству медицинских услуг Министерства здравоохранения Республики Казахстан от «28» июля 2023 года. Протокол № 185. 47 с. Режим доступа: https://nrchd.kz/files/документы%202024/КП%20АНУ_одобрен%20ОКК%2023.pdf. [Дата обращения: 10.01.2025].</mixed-citation><mixed-citation xml:lang="en">Clinical protocol for diagnosis and treatment. Antenatal care. Approved by the Joint Commission on the Quality of Medical Services of the Ministry of Health of the Republic of Kazakhstan dated of July 28, 2023. [Klinicheskij protokol diagnostiki i lecheniya. Antenatal'nyj uhod. Odobren Ob"edinennoj komissiej po kachestvu medicinskih uslug Ministerstva zdravoohraneniya Respubliki Kazahstan ot «28» iyulya 2023 goda]. Protokol № 185. 47 p. (In Russ.). Available at: https://nrchd.kz/files/dokumenty%202024/KP%20ANU_odobren%20OKK%2023.pdf. [Accessed: 10.01.2025].</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
