akusherstvoObstetrics, Gynecology and ReproductionАкушерство, Гинекология и Репродукция2313-73472500-3194IRBIS LLC10.17749/2313-7347/ob.gyn.rep.2025.580akusherstvo-2350Research ArticleFROM HISTORYИЗ ИСТОРИИRobert Geoffrey Edwards – a pioneer of IVF practiceРоберт Джеффри Эдвардс – пионер практики ЭКОhttps://orcid.org/0009-0000-1813-542XАбдулкадыровС. М.AbdulkadyrovS. M.

Абдулкадыров Сафиюла Магомедович

119991 Москва, ул. Трубецкая, д. 8, стр. 2

Safiula M. Abdulkadyrov

8 bldg. 2, Trubetskaya Str., Moscow 119991

https://orcid.org/0009-0000-2174-6045КарапетянМ. У.KarapetyanM. U.

Карапетян Мария Унановна 

603000 Нижний Новгород, площадь Минина и Пожарского, д. 10/1

Mariya U. Karapetyan

10/1 Minin and Pozharsky Square, Nizhny Novgorod 603005

https://orcid.org/0009-0004-7129-7355ТугушеваР. А.TuguschevaR. A.

Тугушева Рената Аркадьевна

603000 Нижний Новгород, площадь Минина и Пожарского, д. 10/1

Renata A. Tuguscheva

10/1 Minin and Pozharsky Square, Nizhny Novgorod 603005

https://orcid.org/0009-0002-2242-1327ПоляковаТ. Е.PolyakovaT. E.

Полякова Татьяна Евгеньевна

WoS ResearcherID: LSJ-7886-2024

119991 Москва, ул. Трубецкая, д. 8, стр. 2

Tatyana E. Polyakova, MD.

8 bldg. 2, Trubetskaya Str., Moscow 119991

te.polyakova@yandex.ruhttps://orcid.org/0000-0002-4509-9281ВоробьевА. В.VorobevA. V.

Воробьев Александр Викторович, к.м.н.

Scopus Author ID: 57191966265

Wos ResearcherID: F-8804-2017

119991 Москва, ул. Трубецкая, д. 8, стр. 2

Alexander V. Vorobev, MD, PhD.

8 bldg. 2, Trubetskaya Str., Moscow 119991

ФГАОУ ВО Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский Университет)РоссияSechenov UniversityRussian FederationФГБОУ ВО «Приволжский исследовательский медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияPrivolzhsky Research Medical University, Ministry of Health of the Russian FederationRussian Federation202506032025191136141Copyright © Abdulkadyrov S.M., Karapetyan M.U., Tuguscheva R.A., Polyakova T.E., Vorobev A.V., 20252025Абдулкадыров С.М., Карапетян М.У., Тугушева Р.А., Полякова Т.Е., Воробьев А.В.Abdulkadyrov S.M., Karapetyan M.U., Tuguscheva R.A., Polyakova T.E., Vorobev A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.gynecology.su/jour/article/view/2350

Here, we discuss the historical aspects of the life and scientific work of the British scientist Robert Geoffrey Edwards, who made a significant contribution to the development of reproductive medicine and genetics. Having begun with studying mouse physiology, together with colleagues he succeeded in proposing in vitro fertilization technique, which in 1978 led to the birth of Louise Brown, the world's first "test-tube baby". In 2010, Dr. Edwards was awarded the Nobel Prize in Physiology or Medicine for the development of human in vitro fertilization.

В статье рассматриваются исторические аспекты жизни и научной деятельности британского ученого Роберта Джеффри Эдвардса, внесшего значительный вклад в развитие репродуктологии и генетики. Начав с изучения физиологии мышей, он с коллегами добился успеха в экстракорпоральном оплодотворении, что привело к рождению Луизы Браун в 1978 г. – первого ребенка «из пробирки». В 2010 г. Эдвардсу была присуждена Нобелевская премия по физиологии и медицине за разработку метода искусственного оплодотворения in vitro.

история медициныРоберт Джеффри Эдвардсгенетикаэкстракорпоральное оплодотворениеЭКОбесплодиеhistory of medicineRobert Geoffrey Edwardsgeneticsin vitro fertilizationIVFinfertilityReferencesEdwards R.G., Steptoe P.C. A matter of life: the story of a medical breakthrough. London: Hutchinson, 1980. 188 p.Edwards R.G., Steptoe P.C. A matter of life: the story of a medical breakthrough. London: Hutchinson, 1980. 188 p.Slee J. RGE at 25 – personal reminiscences. Reprod Biomed Online. 2002;4 Suppl 1:1. https://doi.org/10.1016/s1472-6483(12)60001-7.Slee J. RGE at 25 – personal reminiscences. Reprod Biomed Online. 2002;4 Suppl 1:1. https://doi.org/10.1016/s1472-6483(12)60001-7.Edwards R.G. An astonishing journey into reproductive genetics since the 1950’s. Reprod Nutr. Dev. 2005;45(3):299–306. https://doi.org/10.1051rnd:2005022.Edwards R.G. An astonishing journey into reproductive genetics since the 1950’s. Reprod Nutr. Dev. 2005;45(3):299–306. https://doi.org/10.1051rnd:2005022.Fowler R.E., Edwards R.G. Induction of superovulation and pregnancy in mature mice by gonadotrophins. J Endocr. 1957;15(4):374–84. https://doi.org/10.1677/joe.0.0150374.Fowler R.E., Edwards R.G. Induction of superovulation and pregnancy in mature mice by gonadotrophins. J Endocr. 1957;15(4):374–84. https://doi.org/10.1677/joe.0.0150374.Edwards R.G., Gates A.H. Timing of the stages of the maturation divisions, ovulation, fertilization and the first cleavage of eggs of adult mice treated with gonadotrophins. J Endocr. 1959;18(3):292–304. https://doi.org/10.1677/joe.0.0180292.Edwards R.G., Gates A.H. Timing of the stages of the maturation divisions, ovulation, fertilization and the first cleavage of eggs of adult mice treated with gonadotrophins. J Endocr. 1959;18(3):292–304. https://doi.org/10.1677/joe.0.0180292.Gardner R.L., Johnson M.H. Bob Edwards and the first decade of reproductive biomedicine. Online Reprod Biomed Online. 2011;22(2):106– 24. https://doi.org/10.1016/j.rbmo.2010.11.010.Gardner R.L., Johnson M.H. Bob Edwards and the first decade of reproductive biomedicine. Online Reprod Biomed Online. 2011;22(2):106– 24. https://doi.org/10.1016/j.rbmo.2010.11.010.Edwards R.G. Meiosis in ovarian oocytes of adult mammals. Nature. 1962;196:446–50.Edwards R.G. Meiosis in ovarian oocytes of adult mammals. Nature. 1962;196:446–50.Edwards R.G. Maturation in vitro of human ovarian oocytes. Lancet. 1965;2(7419):926–9. https://doi.org/10.1016/s0140-6736(65)92903-x.Edwards R.G. Maturation in vitro of human ovarian oocytes. Lancet. 1965;2(7419):926–9. https://doi.org/10.1016/s0140-6736(65)92903-x.Edwards R.G., Talbert L., Israelstam D. et al. Diffusion chamber for exposing spermatozoa to human uterine secretions. Am J Obstet Gynecol. 1968;102(3):388–96. https://doi.org/10.1016/0002-9378(68)90011-2.Edwards R.G., Talbert L., Israelstam D. et al. Diffusion chamber for exposing spermatozoa to human uterine secretions. Am J Obstet Gynecol. 1968;102(3):388–96. https://doi.org/10.1016/0002-9378(68)90011-2.Bavister B.D. Environmental factors important for in vitro fertilization in the hamster. J Reprod Fertil. 1969;18(3):544–5. https://doi.org/10.1530/jrf.0.0180544.Bavister B.D. Environmental factors important for in vitro fertilization in the hamster. J Reprod Fertil. 1969;18(3):544–5. https://doi.org/10.1530/jrf.0.0180544.Edwards R.G., Bavister B.D., Steptoe P.C. Early stages of fertilization in vitro of human oocytes matured in vitro. Nature. 1969;221(5181):632–5. https://doi.org/.1038/221632a0.Edwards R.G., Bavister B.D., Steptoe P.C. Early stages of fertilization in vitro of human oocytes matured in vitro. Nature. 1969;221(5181):632–5. https://doi.org/.1038/221632a0.Edwards R.G., Steptoe P.C. Birth after the reimplantation of a human embryo. Lancet. 1978;312(8085):366. https://doi.org/10.1016/s0140-6736(78)92957-4.Edwards R.G., Steptoe P.C. Birth after the reimplantation of a human embryo. Lancet. 1978;312(8085):366. https://doi.org/10.1016/s0140-6736(78)92957-4.Johnson M.H. Robert Edwards: the path to IVF. Reprod Biomed Online. 2011;23(2):245–62. https://doi.org/10.1016/j.rbmo.2011.04.010.Johnson M.H. Robert Edwards: the path to IVF. Reprod Biomed Online. 2011;23(2):245–62. https://doi.org/10.1016/j.rbmo.2011.04.010.The Nobel Prize in Physiology or Medicine 2010 to Robert G. Edwards for the development of in vitro fertilization. Available at: https://web.archive.org/web/20101005215712/http://nobelprize.org/nobel_prizes/medicine/laureates/2010/press.html. [Accessed: 15.09.2024].The Nobel Prize in Physiology or Medicine 2010 to Robert G. Edwards for the development of in vitro fertilization. Available at: https://web.archive.org/web/20101005215712/http://nobelprize.org/nobel_prizes/medicine/laureates/2010/press.html. [Accessed: 15.09.2024].

The authors declare that there are no conflicts of interest present.