Introduction

akusherstvo

Obstetrics, Gynecology and Reproduction

Акушерство, Гинекология и Репродукция

2313-73472500-3194

IRBIS LLC

10.17749/2313-7347/ob.gyn.rep.2024.564

akusherstvo-2254

Research Article

REVIEW ARTICLES

НАУЧНЫЕ ОБЗОРЫ

The influence of environmental factors on woman's reproductive health

Влияние факторов окружающей среды на репродуктивное здоровье женщины

https://orcid.org/0009-0000-7292-2694

Жирнов

И. А.

Zhirnov

I. A.

Жирнов Игорь Александрович

620028 Екатеринбург, ул. Репина, д. 3

Igor A. Zhirnov

3 Repina Str., Ekaterinburg 620028

zhirnovigor33@mail.ru

https://orcid.org/0000-0001-6745-219X

Назмиева

К. А.

Nazmieva

K. A.

Назмиева Ксения Александровна

450008, Уфа, ул. Ленина, д. 3

Ksenia A. Nazmieva, MD

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0004-6181-7070

Хабибуллина

А. И.

Khabibullina

A. I.

Хабибуллина Айгуль Ильнуровна

450008, Уфа, ул. Ленина, д. 3

Aigul I. Khabibullina

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0003-5249-5244

Ильясова

Л. А.

Ilyasova

L. A.

Ильясова Лейсан Альфритовна

450008, Уфа, ул. Ленина, д. 3

Leysan A. Ilyasova

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0009-4575-2525

Саидмурсалова

Н. С.

Saidmursalova

N. S.

Саидмурсалова Нилуфар Сайфуллоевна

450008, Уфа, ул. Ленина, д. 3

Nilufar S. Saidmursalova

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0001-9325-4637

Демишева

Р. Р.

Demisheva

R. R.

Демишева Раяна Рамзановна

364024 Грозный, ул. А. Шерипова, д. 32

Rayana R. Demisheva

32 A. Sheripova Str., Grozny 364024

https://orcid.org/0009-0007-4489-6223

Алихаджиева

П. Е.

Alikhadzhieva

P. E.

Алихаджиева Петимат Ерагиевна

364024 Грозный, ул. А. Шерипова, д. 32

Petimat Е. Alikhadzhieva

32 A. Sheripova Str., Grozny 364024

https://orcid.org/0009-0003-6925-0702

Солтагереева

А. Х.

Soltagereeva

A. Kh.

Солтагереева Аяна Хусайновна

364024 Грозный, ул. А. Шерипова, д. 32

Ayana Kh. Saltagereeva

32 A. Sheripova Str., Grozny 364024

https://orcid.org/0009-0008-0780-6476

Головня

А. А.

Golovnya

A. A.

Головня Алина Андреевна

450008, Уфа, ул. Ленина, д. 3

Alina A. Golovnya

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0005-9684-3882

Кахрамонова

А. В.

Kakhramonova

A. V.

Кахрамонова Анна Владимировна

450008, Уфа, ул. Ленина, д. 3

Anna V. Kakhramonova

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0004-2172-2499

Джалилов

И. М.

Dzhalilov

I. M.

Джалилов Икромджон Мухамаджонович

450008, Уфа, ул. Ленина, д. 3

Ikromjon M. Dzhalilov

3 Lenin Str., Ufa 450008

https://orcid.org/0009-0007-3997-1209

Галимова

У. У.

Galimova

U. U.

Галимова Умакусум Учаровна

410012 Саратов, ул. Большая Казачья, д. 112

Umakusum U. Galimova

112 Bolshaya Kazachya Str., Saratov 410012

ФГБОУ ВО «Уральский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияUral State Medical University, Health Ministry of Russian FederationRussian Federation

ФГБОУ ВО «Башкирский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииРоссияBashkir State Medical University, Health Ministry of Russian FederationRussian Federation

ФГБОУ ВО «Чеченский государственный университет имени А.А. Кадырова»РоссияKadyrov Chechen State UniversityRussian Federation

ФГБОУ ВО «Саратовский государственный медицинский университет имени В.И. Разумовского» Министерства здравоохранения Российской ФедерацииРоссияRazumovsky Saratov State Medical University, Health Ministry of Russian FederationRussian Federation

2024

22112024

186858873

Copyright © Zhirnov I.A., Nazmieva K.A., Khabibullina A.I., Ilyasova L.A., Saidmursalova N.S., Demisheva R.R., Alikhadzhieva P.E., Soltagereeva A.K., Golovnya A.A., Kakhramonova A.V., Dzhalilov I.M., Galimova U.U., 2025

2025

Жирнов И.А., Назмиева К.А., Хабибуллина А.И., Ильясова Л.А., Саидмурсалова Н.С., Демишева Р.Р., Алихаджиева П.Е., Солтагереева А.Х., Головня А.А., Кахрамонова А.В., Джалилов И.М., Галимова У.У.

Zhirnov I.A., Nazmieva K.A., Khabibullina A.I., Ilyasova L.A., Saidmursalova N.S., Demisheva R.R., Alikhadzhieva P.E., Soltagereeva A.K., Golovnya A.A., Kakhramonova A.V., Dzhalilov I.M., Galimova U.U.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.gynecology.su/jour/article/view/2254

Introduction

Introduction. The environment undoubtedly affects the physiological processes in human body, which may be both beneficial and harmful. From 2011 to 2021, the incidence of female infertility in Russia increased by 30 % reaching 789.1 cases per 100,000 women in 2021.

Aim

Aim: to assess an impact of environmental factors including endocrine disrupting chemicals (EDC) on women's reproductive health by assessing available publications.

Materials and Methods

Materials and Methods. Available studies were searched through the scientific literature databases until April 2024 by revealing 5,732 articles in the PubMed/MEDLINE database, 6,587 in Google Scholar and 2,350 in eLibrary. The publications were selected in accordance with PRISMA recommendations. The current review included 90 publications.

Results

Results. Fertility experimental and epidemiological studies showed that environmental factors such as climate, temperature, seasonality, radiation, air pollution, diet and energy balance, working environment, bad habits (e.g. smoking), EDC (plasticizers, heavy metals, parabens, pesticides, industrial chemicals and their by-products, medicines, perfluorochemicals, antibacterial agents) may be associated with impaired female reproductive function.

Conclusion

Conclusion. Environmental factors, including EDC, have a significant impact on women's reproductive health and can negatively affect fertility. The main findings of current research confirm a need to raise awareness of the risks associated with exposure to chemicals on women's body.

Введение

Введение. Окружающая среда, несомненно, влияет на физиологические процессы в организме человека, и это влияние может быть как благоприятным, так и вредным. С 2011 по 2021 гг. в России количество случаев женского бесплодия увеличилось на треть, и в 2021 г. этот показатель достиг 789,1 случая на 100 тыс. женщин.

Цель

Цель: оценить влияние факторов окружающей среды, в том числе химических веществ, нарушающих работу эндокринной системы (англ. endocrine disrupting chemicals, EDC) на репродуктивное здоровье женщин на основании анализа данных литературы.

Материалы и методы

Материалы и методы. Поиск исследований проводили по базам данных научной литературы до апреля 2024 г. В результате поиска было обнаружено 5732 статей в базе данных PubMed/MEDLINE, 6587 в Googl eScholar и 2350 в eLibrary. Публикации отбирали в соответствии с рекомендациями PRISMA. В обзор было включено 90 публикаций.

Результаты

Результаты. Экспериментальные и эпидемиологические исследования, посвященные изучению фертильности, показали, что такие факторы окружающей среды, как климат, температура, сезонность, радиация, загрязнение воздуха, характер питания и энергетический баланс, рабочая среда, вредные привычки (например, курение), EDC (пластификаторы, тяжелые металлы, парабены, пестициды, промышленные химикаты и их побочные продукты, лекарства, перфторохимикаты, антибактериальные средства) могут быть связаны с нарушением репродуктивной функции женщин.

Заключение

Заключение. Факторы окружающей среды, включая EDC, имеют значительное влияние на репродуктивное здоровье женщин и могут негативно сказываться на фертильности. Основные выводы текущих исследований подтверждают необходимость повышения осведомленности о рисках, связанных с воздействием химических веществ на организм.

бесплодиевспомогательные репродуктивные технологиифакторы окружающей средыхимические веществанарушающие работу эндокринной системыEDCэктракорпоральное оплодотворениетоксичность

infertilityassisted reproductive technologiesenvironmental factorsendocrine disrupting chemicalsEDCin vitro fertilizationtoxicity

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The authors declare that there are no conflicts of interest present.