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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">akusherstvo</journal-id><journal-title-group><journal-title xml:lang="en">Obstetrics, Gynecology and Reproduction</journal-title><trans-title-group xml:lang="ru"><trans-title>Акушерство, Гинекология и Репродукция</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2313-7347</issn><issn pub-type="epub">2500-3194</issn><publisher><publisher-name>IRBIS LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.17749/2313-7347/ob.gyn.rep.2022.297</article-id><article-id custom-type="elpub" pub-id-type="custom">akusherstvo-1283</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group></article-categories><title-group><article-title>Generalized actinomycosis of the pelvic organs. Clinical case</article-title><trans-title-group xml:lang="ru"><trans-title>Генерализованный актиномикоз органов малого таза. Клинический случай</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8013-3895</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казакова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazakova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казакова Анна Владимировна – доктор медицинских наук, профессор, зав. кафедрой акушерства и гинекологии № 2 </p><p>443099 Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Anna V. Kazakova – МD, Dr Sci Med, Professor, Head of the Department of Obstetrics and Gynecology № 2 </p><p>89 Chapaevskaya Str., Samara 443099</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2232-0980</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Линева</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lineva</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Линева Ольга Игоревна – доктор медицинских наук, профессор, заслуженный врач Российской Федерации, почетный профессор кафедры акушерства и гинекологии № 2 </p><p>443099 Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Olga I. Lineva – МD, Dr Sci Med, Professor, Honored Doctor of Russian Federation, Honorary Professor of the Department of Obstetrics and Gynecology № 2 </p><p>89 Chapaevskaya Str., Samara 443099</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2108-6053</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трупакова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trupakova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Трупакова Анна Андреевна – соискатель ученой степени, кандидат медицинских наук, кафедра акушерства и гинекологии № 2 </p><p>443099 Самара, ул. Чапаевская, д. 89</p></bio><bio xml:lang="en"><p>Anna A. Trupakova – МD, PhD Аpplicant, Department of Obstetrics and Gynecology № 2 </p><p>89 Chapaevskaya Str., Samara 443099</p></bio><email xlink:type="simple">anantru@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1936-2322</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кияшко</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiyashko</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кияшко Ирина Сергеевна – кандидат медицинских наук, доцент кафедры акушерства и гинекологии № 2; врач акушер-гинеколог </p><p>443099 Самара, ул. Чапаевская, д. 89; 443096 Самара, ул. Полевая, д. 80А</p></bio><bio xml:lang="en"><p>Irina S. Kiyashko – МD, PhD, Associate Professor, Department of Obstetrics and Gynecology № 2; Obstetrician-Gynecologist </p><p>89 Chapaevskaya Str., Samara 443099; 80A Polevaya Str., Samara 443096</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9177-3401</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецова Лилия Васильевна – кандидатмедицинских наук, заведующая гинекологическим отделением для больных с хирургическими и гнойными патологиями № 19 </p><p>443096 Самара, ул. Полевая, д. 80А</p></bio><bio xml:lang="en"><p>Liliya V. Kuznetsova – МD, PhD, Head of the Gynecological Department for Patients with Surgical and Purulent Pathologies № 19 </p><p>80A Polevaya Str., Samara 443096</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6585-9188</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петянова</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Petyanova</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петянова Виктория Александровна – акушер-гинеколог, зам. главного врача по акушерству и гинекологии </p><p>443096 Самара, ул. Полевая, д. 80А</p></bio><bio xml:lang="en"><p>Victoria A. Petyanova – МD, Obstetrician-Gynecologist, Deputy Chief Physician in Obstetrics and Gynecology </p><p>80A Polevaya Str., Samara 443096</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University, Health Ministry of Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Самарский государственный медицинский университет» Министерства здравоохранения Российской Федерации;&#13;
ГБУЗ «Самарская городская клиническая больница № 1 имени Н.И. Пирогова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Medical University, Health Ministry of Russian Federation;&#13;
Pirogov Samara City Clinical Hospital № 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУЗ «Самарская городская клиническая больница № 1 имени Н.И. Пирогова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Samara City Clinical Hospital № 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>06</day><month>04</month><year>2022</year></pub-date><volume>16</volume><issue>3</issue><fpage>317</fpage><lpage>323</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Kazakova A.V., Lineva O.I., Trupakova A.A., Kiyashko I.S., Kuznetsova L.V., Petyanova V.A., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Казакова А.В., Линева О.И., Трупакова А.А., Кияшко И.С., Кузнецова Л.В., Петянова В.А.</copyright-holder><copyright-holder xml:lang="en">Kazakova A.V., Lineva O.I., Trupakova A.A., Kiyashko I.S., Kuznetsova L.V., Petyanova V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.gynecology.su/jour/article/view/1283">https://www.gynecology.su/jour/article/view/1283</self-uri><abstract><p>Here, a clinical case of generalized actinomycosis of the pelvic organs occuring very rarely usually observed in immunocompromised patients is presented. Patient T. referred to the women's clinic with complaints of prolonged genital discharge, itching, burning, and occasional sub-fever. The patient had a history of prolonged hormonal immunosuppressive therapy. After a thorough examination, the patient was consulted by two oncologists. Preliminary diagnosis: suspicio cancer coli; suspicio cancer vaginae. In order to clarify the diagnosis, an in-hospital multifocal scalpel biopsy was performed. The biological material obtained was sent out for intravital pathological and anatomical examination; no signs of malignancy were found. To prevent complications during surgery, the patient underwent separate diagnostic scraping of the uterine cavity and cervical canal after repeated sanitation of the vagina and additional patient examination; hysteroscopy; vulval biopsy; colpocentesis. The final diagnosis was made after obtaining the results of in-surgery microbial culture on nutrient media. Active growth of actinomycetes was detected in the material obtained. The final clinical diagnosis was pelvic actinomycosis, generalized form. Patient T was discharged in satisfactory condition after antibacterial treatment according to the diagnosis for further under gynecologist observation at the women's clinic.</p></abstract><trans-abstract xml:lang="ru"><p>Описан клинический случай генерализованного актиномикоза органов малого таза. Данная патология встречается очень редко и, как правило, у иммунокомпроментированных пациенток. Пациентка Т. обратилась в женскую консультацию с жалобами на длительные выделения из половых путей, зуд, жжение, эпизодический субфебрилитет. В анамнезе длительная гормональная иммуносупрессивная терапия. После проведения тщательного обследования пациентка была проконсультирована двумя онкологами. Предварительный дианоз: Suspicio cancer coli. Suspicio cancer vaginae. Для уточнения диагноза было принято решение о проведении мультифокальной ножевой биопсии в условиях стационара. Полученный материал был направлен на прижизненное патологоанатомическое исследование, признаков злокачественности выявлено не было. После проведения повторной санации влагалища и дополнительного обследования пациентки в целях предупреждения развития осложнений во время операции выполнено раздельное диагностическое выскабливание полости матки и цервикального канала. Гистероскопия. Биопсия вульвы. Кольпоцентез. Окончательный диагноз был выставлен после получения результатов посева микроорганизмов, полученных во время операции на питательные среды. В полученном материале был выявлен активный рост актиномицетов. Выставлен основной клинический диагноз: Актиномикоз органов малого таза, генерализованная форма. После проведенного в соответсnвии с диfгнозом антибактериального лечения пациентка Т. выписана в удовлетворительном состоянии под наблюдение гинеколога в женской консультации.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>псевдомикоз</kwd><kwd>актиномикоз</kwd><kwd>вульвовагинит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pseudomycosis</kwd><kwd>actinomycosis</kwd><kwd>vulvovaginitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Журавель Р.В. Комбинированное лечение актиномикоза перианальной и крестцовокопчиковой областей: Автореф. дис... канд. мед. наук. Ставрополь, 2013. 18 с.</mixed-citation><mixed-citation xml:lang="en">Zhuravel R.V. Complex treatment of actinomycosis of perianal and sacrococcygeal regions. [Kombinirovannoe lechenie aktinomikoza perianal'noj i krestcovo-kopchikovoj oblastej: Avtoref. dis. ... kand. med. nauk]. Stavropol', 2013. 18 p. 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